Researcher - CITAB

2,4-D Herbicide-Induced Hepatotoxicity: Unveiling Disrupted Liver Functions and Associated Biomarkers

Martins R.X., Carvalho M., Maia M.E., Flor B., Souza T., Rocha T.L., Félix L.M., Farias D., (2024) 2,4-D Herbicide-Induced Hepatotoxicity: Unveiling Disrupted Liver Functions and Associated Biomarkers Toxics 12 (35). ISSN: 23056304. doi: 10.3390/toxics12010035.

A Chromogenic Quantification of Protein Expression in Zebrafish Larvae

Félix L., (2024) A Chromogenic Quantification of Protein Expression in Zebrafish Larvae Methods in Molecular Biology 2753 :515-532. ISSN: 19406029. doi: 10.1007/978-1-0716-3625-1_33.

Advancing cortisol measurements in zebrafish: Analytical validation of a commercial ELISA kit for skin mucus cortisol analysis

Jorge S., Félix L., Costas B., Valentim A.M., (2024) Advancing cortisol measurements in zebrafish: Analytical validation of a commercial ELISA kit for skin mucus cortisol analysis MethodsX 12 (102726). ISSN: 22150161. doi: 10.1016/j.mex.2024.102726.

Aloysia citrodora extract as a chemopreventive agent against HPV16-induced lesions: findings from K14-HPV16 mice

Medeiros-Fonseca B., Faustino-Rocha A.I., Silva J., Silva M.G., Pires M.J., Neuparth M.J., Vala H., Vasconcelos-Nóbrega C., Dias M.I., Barros L., Gonçalves L., Gaivão I., Bastos M.M.S.M., Félix L., Venâncio C., Medeiros R., Gil da Costa R.M., Oliveira P.A., (2024) Aloysia citrodora extract as a chemopreventive agent against HPV16-induced lesions: findings from K14-HPV16 mice Exploration of Medicine 5 :416-433. ISSN: 26923106. doi: 10.37349/emed.2024.00228.

Anaesthetic profile of thymol and menthol in zebrafish larvae model

Vieira R.S.F., Sousa D., Félix L.M., Venâncio C.A.S., (2024) Anaesthetic profile of thymol and menthol in zebrafish larvae model Aquaculture and Fisheries ISSN: 2468550X. doi: 10.1016/j.aaf.2024.02.001.

Antinociceptive Analysis of Natural Monoterpenes Eugenol, Menthol, Carvacrol and Thymol in a Zebrafish Larval Model

Rocha C.A., Félix L.M., Monteiro S.M., Venâncio C., (2024) Antinociceptive Analysis of Natural Monoterpenes Eugenol, Menthol, Carvacrol and Thymol in a Zebrafish Larval Model Pharmaceuticals 17 (457). ISSN: 14248247. doi: 10.3390/ph17040457.

Cortisol Quantification for Assessing Stress-Induced Changes in Zebrafish Larvae

Vieira R.S.F., Venâncio C., Félix L., (2024) Cortisol Quantification for Assessing Stress-Induced Changes in Zebrafish Larvae Methods in Molecular Biology 2753 :483-493. ISSN: 19406029. doi: 10.1007/978-1-0716-3625-1_30.

Ecotoxicological Effects of Emerging Contaminants on Aquatic Species

Rocha T.L., Félix L.M., Farias D., (2024) Ecotoxicological Effects of Emerging Contaminants on Aquatic Species Toxics 12 (567). ISSN: 23056304. doi: 10.3390/toxics12080567.

Effects of a Cyperus esculentus L. plant-based beverage on FVB/n female mice

Fernandes F.A., Oliveira P.A., Pinto M.L., Venâncio C., Félix L., Medeiros-Fonseca B., Correia R., Prieto M.A., Ferreira I.C.F.R., Barros L., Heleno S.A., (2024) Effects of a Cyperus esculentus L. plant-based beverage on FVB/n female mice Food and Chemical Toxicology 194 (115082). ISSN: 18736351. doi: 10.1016/j.fct.2024.115082.

Guidelines on Developmental Toxicity Tests: Brief Insights

Alves-Pimenta S., Félix L., Colaço B., Oliveira P.A., Venâncio C., (2024) Guidelines on Developmental Toxicity Tests: Brief Insights Methods in Molecular Biology 2753 :39-65. ISSN: 19406029. doi: 10.1007/978-1-0716-3625-1_2.

Protocol of Geometric Morphometrics for Teratogenicity Testing

Lei M.C., Félix L., Venâncio C., (2024) Protocol of Geometric Morphometrics for Teratogenicity Testing Methods in Molecular Biology 2753 :459-468. ISSN: 19406029. doi: 10.1007/978-1-0716-3625-1_28.

Unveil the toxicity induced on early life stages of zebrafish (Danio rerio) exposed to 3,4-methylenedioxymethamphetamine (MDMA) and its enantiomers

Ribeiro O., Félix L., Ribeiro C., Torres-Ruiz M., Tiritan M.E., Gonçalves V.M.F., Langa I., Carrola J.S., (2024) Unveil the toxicity induced on early life stages of zebrafish (Danio rerio) exposed to 3,4-methylenedioxymethamphetamine (MDMA) and its enantiomers Science of the Total Environment 955 (176906). ISSN: 18791026. doi: 10.1016/j.scitotenv.2024.176906.

A meta-analytic review of monoterpene for fish anaesthesia

Félix L., Vieira R., Monteiro S.M., Venâncio C., (2023) A meta-analytic review of monoterpene for fish anaesthesia Fish and Fisheries 24 :367-380. ISSN: 14672979. doi: 10.1111/faf.12731.

Anti-Inflammatory, Anti-Oxidative and Anti-Apoptotic Effects of Thymol and 24-Epibrassinolide in Zebrafish Larvae

Lanzarin G.A.B., Félix L.M., Monteiro S.M., Ferreira J.M., Oliveira P.A., Venâncio C., (2023) Anti-Inflammatory, Anti-Oxidative and Anti-Apoptotic Effects of Thymol and 24-Epibrassinolide in Zebrafish Larvae Antioxidants 12 (1297). ISSN: 20763921. doi: 10.3390/antiox12061297.

Effects of acute metaphedrone exposure on the development, behaviour, and DNA integrity of zebrafish (Danio rerio)

Ribeiro O., Ribeiro C., Félix L., Gaivão I., Carrola J.S., (2023) Effects of acute metaphedrone exposure on the development, behaviour, and DNA integrity of zebrafish (Danio rerio) Environmental Science and Pollution Research 30 :49567-49576. ISSN: 16147499. doi: 10.1007/s11356-023-25233-z.

Effects of chronic exposure of naturally weathered microplastics on oxidative stress level, behaviour, and mitochondrial function of adult zebrafish (Danio rerio)

Félix L., Carreira P., Peixoto F., (2023) Effects of chronic exposure of naturally weathered microplastics on oxidative stress level, behaviour, and mitochondrial function of adult zebrafish (Danio rerio) Chemosphere 310 (136895). ISSN: 18791298. doi: 10.1016/j.chemosphere.2022.136895.

Effects of Glyphosate or Glyphosate-Based Herbicide during the Zebrafish Life Cycle: A Review Addressing the Mechanisms of Toxicity

Lanzarin G.A.B., Félix L.M., Fontaínhas-Fernandes A., Monteiro S.M., Venâncio C., (2023) Effects of Glyphosate or Glyphosate-Based Herbicide during the Zebrafish Life Cycle: A Review Addressing the Mechanisms of Toxicity Water (Switzerland) 15 (2276). ISSN: 20734441. doi: 10.3390/w15122276.

Housing Conditions Affect Adult Zebrafish (Danio rerio) Behavior but Not Their Physiological Status

Jorge S., Félix L., Costas B., Valentim A.M., (2023) Housing Conditions Affect Adult Zebrafish (Danio rerio) Behavior but Not Their Physiological Status Animals 13 (1120). ISSN: 20762615. doi: 10.3390/ani13061120.

Longitudinal effects of ketamine on cell proliferation and death in the CNS of zebrafish

Santos C., Valentim A.M., Félix L., Balça-Silva J., Pinto M.L., (2023) Longitudinal effects of ketamine on cell proliferation and death in the CNS of zebrafish NeuroToxicology 97 :78-88. ISSN: 18729711. doi: 10.1016/j.neuro.2023.05.008.

Mitigation of nicotine-induced developmental effects by 24-epibrassinolide in zebrafish

Pereira F., Pereira A., Monteiro S.M., Venâncio C., Félix L., (2023) Mitigation of nicotine-induced developmental effects by 24-epibrassinolide in zebrafish Comparative Biochemistry and Physiology Part - C: Toxicology and Pharmacology 266 (109552). ISSN: 18781659. doi: 10.1016/j.cbpc.2023.109552.

Non-Invasive Biomarkers in Saliva and Eye Infrared Thermography to Assess the Stress Response of Calves during Transport

Lei M.C., Félix L., Cardoso R., Monteiro S.M., Silva S., Venâncio C., (2023) Non-Invasive Biomarkers in Saliva and Eye Infrared Thermography to Assess the Stress Response of Calves during Transport Animals 13 (2311). ISSN: 20762615. doi: 10.3390/ani13142311.

Protective effects of 24-epibrassinolide against the 6-OHDA zebrafish model of Parkinson's disease

Gomes A., Monteiro S.M., Venâncio C., Félix L., (2023) Protective effects of 24-epibrassinolide against the 6-OHDA zebrafish model of Parkinson's disease Comparative Biochemistry and Physiology Part - C: Toxicology and Pharmacology 269 (109630). ISSN: 18781659. doi: 10.1016/j.cbpc.2023.109630.

Study on the antineoplastic and toxicological effects of pomegranate (Punica granatum L.) leaf infusion using the K14-HPV16 transgenic mouse model

Yu M., Gouvinhas I., Pires M.J., Neuparth M.J., Costa R.M.G.d., Medeiros R., Bastos M.M.S.M., Vala H., Félix L., Venâncio C., Barros A.I.R.N.A., Oliveira P.A., (2023) Study on the antineoplastic and toxicological effects of pomegranate (Punica granatum L.) leaf infusion using the K14-HPV16 transgenic mouse model Food and Chemical Toxicology 174 (113689). ISSN: 18736351. doi: 10.1016/j.fct.2023.113689.

Anesthesia Overdose Versus Rapid Cooling for Euthanasia of Adult Zebrafish

Ferreira J.M., Félix L., Jorge S., Monteiro S.M., Olsson I.A.S., Valentim A.M., (2022) Anesthesia Overdose Versus Rapid Cooling for Euthanasia of Adult Zebrafish Zebrafish 19 :148-159. doi: 10.1089/zeb.2022.0001.

Behavioural Aversion and Cortisol Level Assessment When Adult Zebrafish Are Exposed to Different Anaesthetics

Ferreira J.M., Jorge S., Félix L., Morello G.M., Olsson I.A.S., Valentim A.M., (2022) Behavioural Aversion and Cortisol Level Assessment When Adult Zebrafish Are Exposed to Different Anaesthetics Biology 11 (1433). ISSN: 20797737. doi: 10.3390/biology11101433.

Behavioural impairment and oxidative stress by acute exposure of zebrafish to a commercial formulation of tebuconazole

Vieira R.S.F., Venâncio C.A.S., Félix L.M., (2022) Behavioural impairment and oxidative stress by acute exposure of zebrafish to a commercial formulation of tebuconazole Environmental Toxicology and Pharmacology 91 (103823). ISSN: 18727077. doi: 10.1016/j.etap.2022.103823.

Beneficial Effects of Broccoli (Brassica oleracea var italica) By-products in Diet-induced Obese Mice

Martins T., Leite R., Matos A.F., Soares J., Pires M.J., de Lurdes Pinto M., Neuparth M.J., Sequeira A.R., Félix L., Venâncio C., Monteiro S.M., Colaço B., Gouvinhas I., Barros A.I., Rosa E., Oliveira P.A., Antunes L.M., (2022) Beneficial Effects of Broccoli (Brassica oleracea var italica) By-products in Diet-induced Obese Mice In Vivo 36 :2173-2185. ISSN: 17917549. doi: 10.21873/invivo.12943.

Chemical Composition and Potential Biological Activity of Melanoidins From Instant Soluble Coffee and Instant Soluble Barley: A Comparative Study

Antonietti S., Silva A.M., Simões C., Almeida D., Félix L.M., Papetti A., Nunes F.M., (2022) Chemical Composition and Potential Biological Activity of Melanoidins From Instant Soluble Coffee and Instant Soluble Barley: A Comparative Study Frontiers in Nutrition 9 (825584). ISSN: 2296861X. doi: 10.3389/fnut.2022.825584.

Effect of a Sub-Chronic Oral Exposure of Broccoli (Brassica oleracea L. Var. Italica) By-Products Flour on the Physiological Parameters of FVB/N Mice: A Pilot Study

Martins T., Oliveira P.A., Pires M.J., Neuparth M.J., Lanzarin G., Félix L., Venâncio C., Pinto M.d.L., Ferreira J., Gaivão I., Barros A.I., Rosa E., Antunes L.M., (2022) Effect of a Sub-Chronic Oral Exposure of Broccoli (Brassica oleracea L. Var. Italica) By-Products Flour on the Physiological Parameters of FVB/N Mice: A Pilot Study Foods 11 (120). ISSN: 23048158. doi: 10.3390/foods11010120.

Enantioselective Ecotoxicity of Venlafaxine in Aquatic Organisms: Daphnia and Zebrafish

Ribeiro O., Félix L., Ribeiro C., Castro B., Tiritan M.E., Monteiro S.M., Carrola J.S., (2022) Enantioselective Ecotoxicity of Venlafaxine in Aquatic Organisms: Daphnia and Zebrafish Environmental Toxicology and Chemistry 41 :1851-1864. ISSN: 15528618. doi: 10.1002/etc.5338.

Evaluation of the developmental effects of a glyphosate-based herbicide complexed with copper, zinc, and manganese metals in zebrafish.

Lanzarin G.A.B., Venâncio C.A.S., Félix L.M., Monteiro S.M., (2022) Evaluation of the developmental effects of a glyphosate-based herbicide complexed with copper, zinc, and manganese metals in zebrafish. Chemosphere 308 (136430). ISSN: 18791298. doi: 10.1016/j.chemosphere.2022.136430.

Histological alterations and oxidative stress in adult zebrafish muscle after aluminium exposure

Ferrandino I., Capriello T., Félix L.M., Di Meglio G., Santos D., Monteiro S.M., (2022) Histological alterations and oxidative stress in adult zebrafish muscle after aluminium exposure Environmental Toxicology and Pharmacology 94 (103934). ISSN: 18727077. doi: 10.1016/j.etap.2022.103934.

Microplastics and copper induce apoptosis, alter neurocircuits, and cause behavioral changes in zebrafish (Danio rerio) brain

Santos D., Luzio A., Félix L., Cabecinha E., Bellas J., Monteiro S.M., (2022) Microplastics and copper induce apoptosis, alter neurocircuits, and cause behavioral changes in zebrafish (Danio rerio) brain Ecotoxicology and Environmental Safety 242 (113926). ISSN: 10902414. doi: 10.1016/j.ecoenv.2022.113926.

Oxidative stress as the trigger for menthol-induced developmental alterations in zebrafish (Danio rerio) model

Carneiro P., Vieira R., Venâncio C., Félix L., (2022) Oxidative stress as the trigger for menthol-induced developmental alterations in zebrafish (Danio rerio) model Journal of Environmental Chemical Engineering 10 (108323). ISSN: 22133437. doi: 10.1016/j.jece.2022.108323.

Oxidative stress, apoptosis and serotonergic system changes in zebrafish (Danio rerio) gills after long-term exposure to microplastics and copper

Santos D., Luzio A., Félix L., Bellas J., Monteiro S.M., (2022) Oxidative stress, apoptosis and serotonergic system changes in zebrafish (Danio rerio) gills after long-term exposure to microplastics and copper Comparative Biochemistry and Physiology Part - C: Toxicology and Pharmacology 258 (109363). ISSN: 18781659. doi: 10.1016/j.cbpc.2022.109363.

Supplementation of an Anthocyanin-Rich Elderberry (Sambucus nigra L.) Extract in FVB/n Mice: A Healthier Alternative to Synthetic Colorants

Azevedo T., Ferreira T., Ferreira J., Teixeira F., Ferreira D., Silva-Reis R., Neuparth M.J., Pires M.J., Pinto M.d.L., Gil da Costa R.M., Bastos M.M.S.M., Medeiros R., Félix L., Venâncio C., Dias M.I., Gaivão I., Barros L., Oliveira P.A., (2022) Supplementation of an Anthocyanin-Rich Elderberry (Sambucus nigra L.) Extract in FVB/n Mice: A Healthier Alternative to Synthetic Colorants Applied Sciences (Switzerland) 12 (11928). ISSN: 20763417. doi: 10.3390/app122311928.

Toxicity of microplastics and copper, alone or combined, in blackspot seabream (Pagellus bogaraveo) larvae

Santos D., Perez M., Perez E., Cabecinha E., Luzio A., Félix L., Monteiro S.M., Bellas J., (2022) Toxicity of microplastics and copper, alone or combined, in blackspot seabream (Pagellus bogaraveo) larvae Environmental Toxicology and Pharmacology 91 (103835). ISSN: 18727077. doi: 10.1016/j.etap.2022.103835.

24-Epibrassinolide modulates the neurodevelopmental outcomes of high caffeine exposure in zebrafish (Danio rerio) embryos

Félix L., Lobato-Freitas C., Monteiro S.M., Venâncio C., (2021) 24-Epibrassinolide modulates the neurodevelopmental outcomes of high caffeine exposure in zebrafish (Danio rerio) embryos Comparative Biochemistry and Physiology Part - C: Toxicology and Pharmacology 249 (109143). ISSN: 18781659. doi: 10.1016/j.cbpc.2021.109143.

Apoptosis, oxidative stress and genotoxicity in developing zebrafish after aluminium exposure

Capriello T., Monteiro S.M., Félix L.M., Donizetti A., Aliperti V., Ferrandino I., (2021) Apoptosis, oxidative stress and genotoxicity in developing zebrafish after aluminium exposure Aquatic Toxicology 236 (105872). ISSN: 18791514. doi: 10.1016/j.aquatox.2021.105872.

Embryonic zebrafish response to a commercial formulation of azoxystrobin at environmental concentrations

Vieira R.S.F., Venâncio C.A.S., Félix L.M., (2021) Embryonic zebrafish response to a commercial formulation of azoxystrobin at environmental concentrations Ecotoxicology and Environmental Safety 211 (111920). ISSN: 10902414. doi: 10.1016/j.ecoenv.2021.111920.

Exposure to aluminium causes behavioural alterations and oxidative stress in the brain of adult zebrafish

Capriello T., Félix L.M., Monteiro S.M., Santos D., Cofone R., Ferrandino I., (2021) Exposure to aluminium causes behavioural alterations and oxidative stress in the brain of adult zebrafish Environmental Toxicology and Pharmacology 85 (103636). ISSN: 18727077. doi: 10.1016/j.etap.2021.103636.

Inflammatory, oxidative stress, and apoptosis effects in zebrafish larvae after rapid exposure to a commercial glyphosate formulation

Lanzarin G., Venâncio C., Félix L.M., Monteiro S., (2021) Inflammatory, oxidative stress, and apoptosis effects in zebrafish larvae after rapid exposure to a commercial glyphosate formulation Biomedicines 9 (1784). ISSN: 22279059. doi: 10.3390/biomedicines9121784.

Malformations and mortality in zebrafish early stages associated with elevated caspase activity after 24 h exposure to MS-222

Félix L.M., Luzio A., Antunes L., Coimbra A.M., Valentim A.M., (2021) Malformations and mortality in zebrafish early stages associated with elevated caspase activity after 24 h exposure to MS-222 Toxicology and Applied Pharmacology 412 (115385). ISSN: 10960333. doi: 10.1016/j.taap.2020.115385.

Microplastics alone or co-exposed with copper induce neurotoxicity and behavioral alterations on zebrafish larvae after a subchronic exposure

Santos D., Luzio A., Matos C., Bellas J., Monteiro S.M., Félix L., (2021) Microplastics alone or co-exposed with copper induce neurotoxicity and behavioral alterations on zebrafish larvae after a subchronic exposure Aquatic Toxicology 235 (105814). ISSN: 18791514. doi: 10.1016/j.aquatox.2021.105814.

Ms-222 and propofol sedation during and after the simulated transport of nile tilapia (Oreochromis niloticus)

Félix L., Correia R., Sequeira R., Ribeiro C., Monteiro S., Antunes L., Silva J., Venâncio C., Valentim A., (2021) Ms-222 and propofol sedation during and after the simulated transport of nile tilapia (Oreochromis niloticus) Biology 10 (1309). ISSN: 20797737. doi: 10.3390/biology10121309.

Multi-biomarker responses of Asian clam Corbicula fluminea (bivalvia, corbiculidea) to cadmium and microplastics pollutants

Parra S., Varandas S., Santos D., Félix L., Fernandes L., Cabecinha E., Gago J., Monteiro S.M., (2021) Multi-biomarker responses of Asian clam Corbicula fluminea (bivalvia, corbiculidea) to cadmium and microplastics pollutants Water (Switzerland) 13 (394). ISSN: 20734441. doi: 10.3390/w13040394.

Orange thyme: Phytochemical profiling, in vitro bioactivities of extracts and potential health benefits

Silva A.M., Félix L.M., Teixeira I., Martins-Gomes C., Schäfer J., Souto E.B., Santos D.J., Bunzel M., Nunes F.M., (2021) Orange thyme: Phytochemical profiling, in vitro bioactivities of extracts and potential health benefits Food Chemistry: X 12 (100171). ISSN: 25901575. doi: 10.1016/j.fochx.2021.100171.

Single and combined acute and subchronic toxic effects of microplastics and copper in zebrafish (Danio rerio) early life stages

Santos D., Félix L., Luzio A., Parra S., Bellas J., Monteiro S.M., (2021) Single and combined acute and subchronic toxic effects of microplastics and copper in zebrafish (Danio rerio) early life stages Chemosphere 277 (130262). ISSN: 18791298. doi: 10.1016/j.chemosphere.2021.130262.

Teratogenic, oxidative stress and behavioural outcomes of three fungicides of natural origin (Equisetum arvense, mimosa tenuiflora, thymol) on zebrafish (danio rerio)

Vieira R., Venâncio C., Félix L., (2021) Teratogenic, oxidative stress and behavioural outcomes of three fungicides of natural origin (Equisetum arvense, mimosa tenuiflora, thymol) on zebrafish (danio rerio) Toxics 9 (8) :1-15. ISSN: 23056304. doi: 10.3390/toxics9010008.

Toxicological and anti-tumor effects of a linden extract (: Tilia platyphyllos Scop.) in a HPV16-transgenic mouse model

Ferreira T., Nascimento-Gonçalves E., Macedo S., Borges I., Gama A., M. Gil Da Costa R., Neuparth M.J., Lanzarin G., Venâncio C., Félix L., Gaivão I., Alvarado A., Pires M.J., Bastos M.M.S.M., Medeiros R., Nogueira A., Barros L., Ferreira I.C.F.R., Rosa E., Oliveira P.A., (2021) Toxicological and anti-tumor effects of a linden extract (: Tilia platyphyllos Scop.) in a HPV16-transgenic mouse model Food and Function 12 :4005-4014. ISSN: 2042650X. doi: 10.1039/d1fo00225b.

24-Epibrassinolide protects against ethanol-induced behavioural teratogenesis in zebrafish embryo

Fernandes P., Monteiro S.M., Venâncio C., Félix L., (2020) 24-Epibrassinolide protects against ethanol-induced behavioural teratogenesis in zebrafish embryo Chemico-Biological Interactions 328 (109193). ISSN: 18727786. doi: 10.1016/j.cbi.2020.109193.

Behavioural toxicity of environmental relevant concentrations of a glyphosate commercial formulation - RoundUp® UltraMax - During zebrafish embryogenesis

Lanzarin G.A.B., Venâncio C.A.S., Monteiro S.M., Félix L.M., (2020) Behavioural toxicity of environmental relevant concentrations of a glyphosate commercial formulation - RoundUp® UltraMax - During zebrafish embryogenesis Chemosphere 253 (126636). ISSN: 18791298. doi: 10.1016/j.chemosphere.2020.126636.

Dietary supplementation with chestnut (Castanea sativa) reduces abdominal adiposity in FVB/n mice: A preliminary study

Rodrigues P., Ferreira T., Nascimento-Gonçalves E., Seixas F., da Costa R.M.G., Martins T., Neuparth M.J., Pires M.J., Lanzarin G., Félix L., Venâncio C., Ferreira I.C.F.R., Bastos M.M.S.M., Medeiros R., Gaivão I., Rosa E., Oliveira P.A., (2020) Dietary supplementation with chestnut (Castanea sativa) reduces abdominal adiposity in FVB/n mice: A preliminary study Biomedicines 8 (75). ISSN: 22279059. doi: 10.3390/biomedicines8040075.

MS-222 induces biochemical and transcriptional changes related to oxidative stress, cell proliferation and apoptosis in zebrafish embryos

Félix L.M., Luzio A., Santos A., Antunes L.M., Coimbra A.M., Valentim A.M., (2020) MS-222 induces biochemical and transcriptional changes related to oxidative stress, cell proliferation and apoptosis in zebrafish embryos Comparative Biochemistry and Physiology Part - C: Toxicology and Pharmacology 237 (108834). ISSN: 18781659. doi: 10.1016/j.cbpc.2020.108834.

Polyphenol composition and biological activity of Thymus citriodorus and Thymus vulgaris: Comparison with endemic Iberian Thymus species

Taghouti M., Martins-Gomes C., Félix L.M., Schäfer J., Santos J.A., Bunzel M., Nunes F.M., Silva A.M., (2020) Polyphenol composition and biological activity of Thymus citriodorus and Thymus vulgaris: Comparison with endemic Iberian Thymus species Food Chemistry 331 (127362). ISSN: 18737072. doi: 10.1016/j.foodchem.2020.127362.

Toxic effects of a mancozeb-containing commercial formulation at environmental relevant concentrations on zebrafish embryonic development

Vieira R., Venâncio C.A.S., Félix L.M., (2020) Toxic effects of a mancozeb-containing commercial formulation at environmental relevant concentrations on zebrafish embryonic development Environmental Science and Pollution Research 27 :21174-21187. ISSN: 16147499. doi: 10.1007/s11356-020-08412-0.

Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper

Santos D., Félix L., Luzio A., Parra S., Cabecinha E., Bellas J., Monteiro S.M., (2020) Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper Chemosphere 261 (127748). ISSN: 18791298. doi: 10.1016/j.chemosphere.2020.127748.

Dose-dependent effects of a glyphosate commercial formulation – Roundup^® UltraMax - on the early zebrafish embryogenesis

Lanzarin G.A.B., Félix L.M., Santos D., Venâncio C.A.S., Monteiro S.M., (2019) Dose-dependent effects of a glyphosate commercial formulation – Roundup^® UltraMax - on the early zebrafish embryogenesis Chemosphere 223 :514-522. ISSN: 18791298. doi: 10.1016/j.chemosphere.2019.02.071.

Review on the use of zebrafish embryos to study the effects of anesthetics during early development

Félix L., Coimbra A.M., Valentim A.M., Antunes L., (2019) Review on the use of zebrafish embryos to study the effects of anesthetics during early development Critical Reviews in Toxicology 49 :357-370. ISSN: 15476898. doi: 10.1080/10408444.2019.1617236.

Evaluation of anaesthetic protocols for laboratory adult zebrafish(Danio rerio).

Martins, Tania; Diniz, Enoque; Felix, Luis M.; Antunes, Luis (2018) Evaluation of anaesthetic protocols for laboratory adult zebrafish(Danio rerio). Plos One 13 (5). doi: 10.1371/journal.pone.0197846. (Impact factor, Quartile: 2.766, Q1).

Ketamine induction of p53-dependent apoptosis and oxidative stress in zebrafish (Danio rerio) embryos.

Felix, Luis M.; Vidal, Ana M.; Serafim, Cindy; Valentim, Ana M.; Antunes, Luis M.; Monteiro, Sandra M.; Matos, Manuela; Coimbra, Ana M. (2018) Ketamine induction of p53-dependent apoptosis and oxidative stress in zebrafish (Danio rerio) embryos. Chemosphere 201 :730-739. doi: 10.1016/j.chemosphere.2018.03.049. (Impact factor, Quartile: 4.427, Q1).

Laurus nobilis (laurel) aqueous leaf extract's toxicological and anti-tumor activities in HPV16-transgenic mice.

Medeiros-Fonseca, B; Mestre, VF; Colaço, B; Pires, MJ; Martins, T; Gil da Costa, RM; Neuparth, MJ; Medeiros, R; Moutinho, MSS; Dias, MI; Barros, L; Bastos, MMSM; Félix, L; Venâncio, C; Ferreira, ICFR; Antunes, LM; Oliveira, PA. (2018) Laurus nobilis (laurel) aqueous leaf extract's toxicological and anti-tumor activities in HPV16-transgenic mice. FOOD & FUNCTION 9 :4419-4428. doi: 10.1039/c8fo00783g. (Impact factor, Quartile: 3.289, Q1).

MS-222 short exposure induces developmental and behavioural alterations in zebrafish embryos.

Felix, L.M.; Luzio, A.; Themudo, M.; Antunes, L.; Matos, M.; Coimbra, A.M.; Valentim, A.M. (2018) MS-222 short exposure induces developmental and behavioural alterations in zebrafish embryos. Reproductive Toxicology 81 :122-131. doi: 10.1016/j.reprotox.2018.07.086. (Impact factor, Quartile: 2.58, Q2).

Thymus pulegioides L. as a rich source of antioxidant, anti-proliferative and neuroprotective phenolic compounds.

Taghouti, Meriem; Martins-Gomes, Carlos; Schaefer, Judith; Felix, Luis M.; Santos, Joao A.; Bunzel, Mirko; Nunes, Fernando M.; Silva, Amelia M. (2018) Thymus pulegioides L. as a rich source of antioxidant, anti-proliferative and neuroprotective phenolic compounds. Food & Function 9 (7) :3617-3629. doi: 10.1039/c8fo00456k. (Impact factor, Quartile: 3.289, Q1).

Apoptosis-related genes induced in response to ketamine during early life stages of zebrafish.

Felix, LM, Serafim, C, Valentim, AM, Antunes, LM, Matos, M, Coimbra, AM (2017) Apoptosis-related genes induced in response to ketamine during early life stages of zebrafish. Toxicology Letters 279 :8-Jan. ISSN: 0378-4274. doi: 10.1016/j.toxlet.2017.07.888. (Impact factor, Quartile: 3.858, Q1).

Behavioral alterations of zebrafish larvae after early embryonic exposure to ketamine.

Felix, LM, Antunes, LM, Coimbra, AM, Valentim, AM (2017) Behavioral alterations of zebrafish larvae after early embryonic exposure to ketamine. Psychopharmacology 234 :549-558. ISSN: 0033-3158. doi: 10.1007/s00213-016-4491-7. (Impact factor, Quartile: 3.308, Q2).

Carvedilol exacerbate gentamicin-induced kidney mitochondrial alterations in adult rat.

Felix, L, Oliveira, MM, Videira, R, Maciel, E, Alves, ND, Nunes, FM, Alves, A, Almeida, JM, Domingues, MRM, Peixoto, FP (2017) Carvedilol exacerbate gentamicin-induced kidney mitochondrial alterations in adult rat. Experimental And Toxicologic Pathology 69 :83-92. ISSN: 0940-2993. doi: 10.1016/j.etp.2016.11.006. (Impact factor, Quartile: 1.975, Q2).

Morphological and behavioral responses of zebrafish after 24h of ketamine embryonic exposure.

Felix, LM, Serafim, C, Martins, MJ, Valentim, AM, Antunes, LM, Matos, M, Coimbra, AM (2017) Morphological and behavioral responses of zebrafish after 24h of ketamine embryonic exposure. Toxicology And Applied Pharmacology 321 :27-36. ISSN: 0041-008X. doi: 10.1016/j.taap.2017.02.013. (Impact factor, Quartile: 3.791, Q1).

Propofol affinity to mitochondrial membranes does not alter mitochondrial function.

Felix, LM, Correia, F, Pinto, PA, Campos, SP, Fernandes, T, Videira, R, Oliveira, MM, Peixoto, FP, Antunes, LM (2017) Propofol affinity to mitochondrial membranes does not alter mitochondrial function. European Journal Of Pharmacology 803 :48-56. ISSN: 0014-2999. doi: 10.1016/j.ejphar.2017.03.044. (Impact factor, Quartile: 2.896, Q2).

Luis Manuel Lourenço Felix Integrated Member

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