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Rui Miguel Gil da Costa Oliveira PhD Collaborator

BIO

Name: Rui Miguel Gil da Costa Oliveira

Aggregation: PhD Collaborator

Orcid ID: 0000-0002-2151-2449

Ciência Vitae: 0318-98C4-ADCF

Email: rmcosta@fe.up.pt

Research Tasks

Valorisation of bio-based products and and co-products

Publications

Appraising Animal Models of Prostate Cancer for Translational Research: Future Directions
Nascimento-Goncalves E., Seixas F., Gil Da Costa R.M., Pires M.J., Neuparth M.J., Moreira-Goncalves D., Fardilha M., Faustino-Rocha A.I., Colaco B., Ferreira R., Oliveira P.A., (2023) Appraising Animal Models of Prostate Cancer for Translational Research: Future Directions Anticancer Research 43 :275-281. ISSN: 17917530. doi: 10.21873/anticanres.16160.
Propolis antibacterial and antioxidant synergisms with gentamicin and honey
Freitas A.S., Cunha A., Oliveira R., Almeida-Aguiar C., (2022) Propolis antibacterial and antioxidant synergisms with gentamicin and honey Journal of Applied Microbiology 132 :2733-2745. ISSN: 13652672. doi: 10.1111/jam.15440.
Pulegone and Eugenol Oral Supplementation in Laboratory Animals: Results from Acute and Chronic Studies
Ribeiro-Silva C.M., Faustino-Rocha A.I., Gil da Costa R.M., Medeiros R., Pires M.J., Gaivão I., Gama A., Neuparth M.J., Barbosa J.V., Peixoto F., Magalhães F.D., Bastos M.M.S.M., Oliveira P.A., (2022) Pulegone and Eugenol Oral Supplementation in Laboratory Animals: Results from Acute and Chronic Studies Biomedicines 10 (2595). ISSN: 22279059. doi: 10.3390/biomedicines10102595.
Supplementation of an Anthocyanin-Rich Elderberry (Sambucus nigra L.) Extract in FVB/n Mice: A Healthier Alternative to Synthetic Colorants
Azevedo T., Ferreira T., Ferreira J., Teixeira F., Ferreira D., Silva-Reis R., Neuparth M.J., Pires M.J., Pinto M.d.L., Gil da Costa R.M., Bastos M.M.S.M., Medeiros R., Félix L., Venâncio C., Dias M.I., Gaivão I., Barros L., Oliveira P.A., (2022) Supplementation of an Anthocyanin-Rich Elderberry (Sambucus nigra L.) Extract in FVB/n Mice: A Healthier Alternative to Synthetic Colorants Applied Sciences (Switzerland) 12 (11928). ISSN: 20763417. doi: 10.3390/app122311928.
Experimental models for studying HPV-positive and HPV-negative penile cancer: New tools for an old disease
Medeiros-Fonseca B., Cubilla A., Brito H., Martins T., Medeiros R., Oliveira P., Gil Da Costa R.M., (2021) Experimental models for studying HPV-positive and HPV-negative penile cancer: New tools for an old disease Cancers 13 (460) :1-15. ISSN: 20726694. doi: 10.3390/cancers13030460.
Pteridium spp. and Bovine Papillomavirus: Partners in Cancer
Medeiros-Fonseca B., Abreu-Silva A.L., Medeiros R., Oliveira P.A., Gil da Costa R.M., (2021) Pteridium spp. and Bovine Papillomavirus: Partners in Cancer Frontiers in Veterinary Science 8 (758720). ISSN: 22971769. doi: 10.3389/fvets.2021.758720.
Dietary supplementation with chestnut (Castanea sativa) reduces abdominal adiposity in FVB/n mice: A preliminary study
Rodrigues P., Ferreira T., Nascimento-Gonçalves E., Seixas F., da Costa R.M.G., Martins T., Neuparth M.J., Pires M.J., Lanzarin G., Félix L., Venâncio C., Ferreira I.C.F.R., Bastos M.M.S.M., Medeiros R., Gaivão I., Rosa E., Oliveira P.A., (2020) Dietary supplementation with chestnut (Castanea sativa) reduces abdominal adiposity in FVB/n mice: A preliminary study Biomedicines 8 (75). ISSN: 22279059. doi: 10.3390/biomedicines8040075.
HPV infection as a risk factor for atherosclerosis: A connecting hypothesis
Reis D.R.A., Medeiros-Fonseca B., Costa J.M., de Oliveira Neto C.P., Gil da Costa R.M., Oliveira P.A., Medeiros R., Bastos M.M.S.M., Brito H.O., Brito L.M.O., (2020) HPV infection as a risk factor for atherosclerosis: A connecting hypothesis Medical Hypotheses 144 (109979). ISSN: 15322777. doi: 10.1016/j.mehy.2020.109979.
HPV16 induces penile intraepithelial neoplasia and squamous cell carcinoma in transgenic mice: first mouse model for HPV-related penile cancer.
Medeiros-Fonseca, B.; Mestre, V.F.; Estêvão, D.; Sánchez, D.F.; Cañete-Portillo, S.; Fernández-Nestosa, M.J.; Casaca, F.; Silva, S.; Brito, H.; Félix, A.; Medeiros, R.; Colaço, B.; Oliveira, P.A.; Bastos, M.M.S.M.; Nelson, P.S.; Vakar-Lopez, F.; Gaivão, I.; Brito, L.; Lopes, C.; Cubilla, A.L.; Gil da Costa, R.M. (2020) HPV16 induces penile intraepithelial neoplasia and squamous cell carcinoma in transgenic mice: first mouse model for HPV-related penile cancer. JOURNAL OF PATHOLOGY 251 (4) :411-419. doi: 10.1002/path.5475.. (Impact factor, Quartile: 6.021, Q1).
HPV16 is sufficient to induce squamous cell carcinoma specifically in the tongue base in transgenic mice
Mestre V.F., Medeiros-Fonseca B., Estêvão D., Casaca F., Silva S., Félix A., Silva F., Colaço B., Seixas F., Bastos M.M.S.M., Lopes C., Medeiros R., Oliveira P.A., Gil da Costa R.M., (2020) HPV16 is sufficient to induce squamous cell carcinoma specifically in the tongue base in transgenic mice Journal of Pathology 251 :4-11. ISSN: 10969896. doi: 10.1002/path.5387.
Human papillomavirus 16-transgenic mice as a model to study cancer-associated cachexia
da Silva S.P., Santos J.M.O., Mestre V.F., Medeiros-Fonseca B., Oliveira P.A., Bastos M.M.S.M., Gil da Costa R.M., Medeiros R., (2020) Human papillomavirus 16-transgenic mice as a model to study cancer-associated cachexia International Journal of Molecular Sciences 21 (5020) :1-17. ISSN: 14220067. doi: 10.3390/ijms21145020.
Ptaquiloside from bracken (: Pteridium spp.) promotes oral carcinogenesis initiated by HPV16 in transgenic mice
Gil Da Costa R.M., Neto T., Estêvão D., Moutinho M., Félix A., Medeiros R., Lopes C., Bastos M.M.S.M., Oliveira P.A., (2020) Ptaquiloside from bracken (: Pteridium spp.) promotes oral carcinogenesis initiated by HPV16 in transgenic mice Food and Function 11 :3298-3305. ISSN: 2042650X. doi: 10.1039/d0fo00207k.
Dietary supplementation with the red seaweed porphyra umbilicalis protects against DNA damage and pre-malignant dysplastic skin lesions in HPV-transgenic mice
Santos S., Ferreira T., Almeida J., Pires M.J., Colaço A., Lemos S., Da Costa R.M.G., Medeiros R., Bastos M.M.S.M., Neuparth M.J., Abreu H., Pereira R., Pacheco M., Gaivão I., Rosa E., Oliveira P.A., (2019) Dietary supplementation with the red seaweed porphyra umbilicalis protects against DNA damage and pre-malignant dysplastic skin lesions in HPV-transgenic mice Marine Drugs 17 (615). ISSN: 16603397. doi: 10.3390/md17110615.
Dimethylaminoparthenolide reduces the incidence of dysplasia and ameliorates a wasting syndrome in HPV16-transgenic mice
Santos J.M.O., Moreira-Pais A., Neto T., Peixoto da Silva S., Oliveira P.A., Ferreira R., Mendes J., Bastos M.M.S.M., Lopes C., Casaca F., Silva S., Sweeney C., Medeiros R., Gil da Costa R.M., (2019) Dimethylaminoparthenolide reduces the incidence of dysplasia and ameliorates a wasting syndrome in HPV16-transgenic mice Drug Development Research 80 :824-830. ISSN: 10982299. doi: 10.1002/ddr.21565.
Hallmarks of HPV carcinogenesis: The role of E6, E7 and E5 oncoproteins in cellular malignancy
Estêvão D., Costa N.R., Gil da Costa R.M., Medeiros R., (2019) Hallmarks of HPV carcinogenesis: The role of E6, E7 and E5 oncoproteins in cellular malignancy Biochimica et Biophysica Acta - Gene Regulatory Mechanisms 1862 :153-162. ISSN: 18764320. doi: 10.1016/j.bbagrm.2019.01.001.
Inhalation of Bacterial Cellulose Nanofibrils triggers an inflammatory response and changes lung tissue morphology of mice
Silva-Carvalho R., Silva J.P., Ferreirinha P., Leitão A.F., Andrade F.K., Gil da Costa R.M., Cristelo C., Rosa M.F., Vilanova M., Gama F.M., (2019) Inhalation of Bacterial Cellulose Nanofibrils triggers an inflammatory response and changes lung tissue morphology of mice Toxicological Research 35 :45-63. ISSN: 22342753. doi: 10.5487/TR.2019.35.1.045.
The cyclooxigenase-2 inhibitor parecoxib prevents epidermal dysplasia in HPV16-transgenic mice: efficacy and safety observations
Ferreira T., Campos S., Silva M.G., Ribeiro R., Santos S., Almeida J., Pires M.J., da Costa R.M.G., Córdova C., Nogueira A., Neuparth M.J., Medeiros R., Bastos M.M.d.S.M., Gaivão I., Peixoto F., Oliveira M.M., Oliveira P.A., (2019) The cyclooxigenase-2 inhibitor parecoxib prevents epidermal dysplasia in HPV16-transgenic mice: efficacy and safety observations International Journal of Molecular Sciences 20 (3902). ISSN: 14220067. doi: 10.3390/ijms20163902.
Curcumin and Rutin Down-regulate Cyclooxygenase-2 and Reduce Tumor-associated Inflammation in HPV16-Transgenic Mice.
Moutinho, M.; Aragão, S.; Carmo, D.; Casaca, F.; Silva, S.; Ribeiro, J.; Sousa, H.; Pires, I.; Queiroga, F.; Colaço, B.; Medeiros, R.; Oliveira, P.A.; Lopes, C.; Bastos, M.; Gil da Costa, R. (2018) Curcumin and Rutin Down-regulate Cyclooxygenase-2 and Reduce Tumor-associated Inflammation in HPV16-Transgenic Mice. Anticancer Research 38 :1461-1466. doi: 10.21873/anticanres.12371. (Impact factor, Quartile: 1.865, Q4).
Dysregulation of cellular microRNAs by human oncogenic viruses - Implications for tumorigenesis.
Santos, Joana M. O.; Gil da Costa, Rui M.; Medeiros, Rui (2018) Dysregulation of cellular microRNAs by human oncogenic viruses - Implications for tumorigenesis. Biochimica Et Biophysica Acta-Gene Regulatory Mechanisms 1861 (2) :95-105. doi: 10.1016/j.bbagrm.2018.01.017. (Impact factor, Quartile: 5.179, Q1).
Expression profile of microRNA-146a along HPV-induced multistep carcinogenesis: a study in HPV16 transgenic mice.
Araujo, Rita; Santos, Joana M. O.; Fernandes, Mara; Dias, Francisca; Sousa, Hugo; Ribeiro, Joana; Bastos, Margarida M. S. M.; Oliveira, Paula A.; Carmo, Diogo; Casaca, Fatima; Silva, Sandra; Medeiros, Rui; Gil da Costa, Rui M. (2018) Expression profile of microRNA-146a along HPV-induced multistep carcinogenesis: a study in HPV16 transgenic mice. Journal Of Cancer Research And Clinical Oncology 144 (2) :241:248. doi: 10.1007/s00432-017-2549-5. (Impact factor, Quartile: 3.282, Q2).
Laurus nobilis (laurel) aqueous leaf extract's toxicological and anti-tumor activities in HPV16-transgenic mice.
Medeiros-Fonseca, B; Mestre, VF; Colaço, B; Pires, MJ; Martins, T; Gil da Costa, RM; Neuparth, MJ; Medeiros, R; Moutinho, MSS; Dias, MI; Barros, L; Bastos, MMSM; Félix, L; Venâncio, C; Ferreira, ICFR; Antunes, LM; Oliveira, PA. (2018) Laurus nobilis (laurel) aqueous leaf extract's toxicological and anti-tumor activities in HPV16-transgenic mice. FOOD & FUNCTION 9 :4419-4428. doi: 10.1039/c8fo00783g. (Impact factor, Quartile: 3.289, Q1).
Ozone therapy prevents the onset of dysplasia in HPV16-transgenic mice-A pre-clinical efficacy and safety analysis.
Peirone, C.; Mestre, V. F.; Medeiros-Fonseca, B.; Colaço, B.; Pires, M. J.; Martins, T.; Gil da Costa, R. M.; Neuparth, M. J.; Medeiros, R.; Bastos, M. M. S. M.; Marques-Magallanes, J. A.; Oliveira, P. A. (2018) Ozone therapy prevents the onset of dysplasia in HPV16-transgenic mice-A pre-clinical efficacy and safety analysis. Biomedicine & Pharmacotherapy 104 :275-279. doi: 10.1016/j.biopha.2018.05.018. (Impact factor, Quartile: 3.457, Q2).
Platinum-induced muscle wasting in cancer chemotherapy: Mechanisms and potential targets for therapeutic intervention.
Moreira-Pais, Alexandra; Ferreira, Rita; da Costa, Rui Gil (2018) Platinum-induced muscle wasting in cancer chemotherapy: Mechanisms and potential targets for therapeutic intervention. Life Sciences 208 :43344. doi: 10.1016/j.lfs.2018.07.010. (Impact factor, Quartile: 3.234, Q2).
Quantitative assessment of DNA damage in the industrial ethanol production strain Saccharomyces cerevisiae PE-2.
Silva, Paulo C,; Domingues, Lucilia; Collins, Tony; Oliveira, Rui; Johansson, Björn (2018) Quantitative assessment of DNA damage in the industrial ethanol production strain Saccharomyces cerevisiae PE-2. FEMS YEAST RESEARCH 18 (8) :foy101. doi: 10.1093/femsyr/foy101. (Impact factor, Quartile: 2.609, Q2).
HPV16 induces a wasting syndrome in transgenic mice: Amelioration by dietary polyphenols via NF-kappa B inhibition.
da Costa, RMG, Aragao, S, Moutinho, M, Alvarado, A, Carmo, D, Casaca, F, Silva, S, Ribeiro, J, Sousa, H, Ferreira, R, Nogueira-Ferreira, R, Pires, MJ, Colaço, B, Medeiros, R, Venancio, C, Oliveira, MM, Bastos, MMSM, Lopes, C, Oliveira, PA (2017) HPV16 induces a wasting syndrome in transgenic mice: Amelioration by dietary polyphenols via NF-kappa B inhibition. Life Sciences 169 :19-Nov. ISSN: 0024-3205. doi: 10.1016/j.lfs.2016.10.031. (Impact factor, Quartile: 2.963, Q2).
Regulation of miRNA-146a and miRNA-150 Levels by Celecoxib in Premalignant Lesions of K14-HPV16 Mice.
Da Costa, RMG, Araujo, R, Santos, JMO, Fernandes, M, Neto, T, Sousa, H, Ribeiro, J, Bastos, MMSM, Oliveira, PA, Carmo, D, Casaca, F, Silva, S, Lopes, C, Medeiros, R (2017) Regulation of miRNA-146a and miRNA-150 Levels by Celecoxib in Premalignant Lesions of K14-HPV16 Mice. Anticancer Research 37 :2913-2918. ISSN: 0250-7005. doi: 10.21873/anticanres.11644. (Impact factor, Quartile: 1.937, Q3).