Pionner animal model of cancer

CITAB researchers Paula Oliveira, Bruno Colaço and Rui Gil da Costa are part of an international team which developed an animal model of penis cancer. This model is of high scientific importance since it associates viral carcinogenesis with chemistry, demonstrating that the development of penis cancer is associated to the exposure to papillomavirus and chemical compounds, reproducing the spectrum of histological lesions identified in this man disease. Within CITAB, this model will allow the assessment of the therapeutic effectiveness of bioactive substances extracted from natural products, valuing their application and allowing the development of new drugs.