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Rui Miguel Gil da Costa Oliveira PhD Collaborator

BIO

Name: Rui Miguel Gil da Costa Oliveira

Aggregation: PhD Collaborator

Orcid ID: 0000-0002-2151-2449

Email: rmcosta@fe.up.pt

URL:

Phone:

Research Tasks

Valorisation of bio-based products and and co-products

Resume

Publications

Experimental Models for Studying HPV-Positive and HPV-Negative Penile Cancer: New Tools for An Old Disease.
Medeiros-Fonseca, B., Cubilla, A., Brito, H., Martins, T., Medeiros, R., Oliveira, P., da Costa, R.M.G. (2021) Experimental Models for Studying HPV-Positive and HPV-Negative Penile Cancer: New Tools for An Old Disease. Cancers 13(3) (460). doi: 10.3390/cancers13030460. (Impact factor, Quartile: 6.639, Q1).
Dietary supplementation with chestnut (Castanea sativa) reduces abdominal adiposity in FVB/n mice: A preliminary study.
Rodrigues, P.; Ferreira, T.; Nascimento-Gonçalves, E.; Seixas, F.; Gil da Costa, R.M.; Martins, T.; Neuparth, M.J.; Pires, M.J.; Lanzarin, G.; Félix, L.; Venâncio, C.; Ferreira, I.C.F.R.; Bastos, M.M.S.M.; Medeiros, R.; Gaivão, I.; Rosa, E.; Oliveira, P.A. (2020) Dietary supplementation with chestnut (Castanea sativa) reduces abdominal adiposity in FVB/n mice: A preliminary study. BIOMEDICINES 8 (4) :75. doi: 10.3390/biomedicines8040075. (Impact factor, Quartile: 4.717, Q1).
HPV infection as a risk factor for atherosclerosis: A connecting hypothesis.
Reis, D.R.A.; Medeiros-Fonseca, B.; Costa, J.M.; de Oliveira Neto, C.P.; Gil da Costa, R.M.; Oliveira, P.A.; Medeiros, R.; Bastos, M.M.S.M.; Brito, H.O.; Brito, L.M.O. (2020) HPV infection as a risk factor for atherosclerosis: A connecting hypothesis. MEDICAL HYPOTHESES 144 :109979. doi: 10.1016/j.mehy.2020.109979. (Impact factor, Quartile: 1.375, Q4).
HPV16 induces penile intraepithelial neoplasia and squamous cell carcinoma in transgenic mice: first mouse model for HPV-related penile cancer.
Medeiros-Fonseca, B.; Mestre, V.F.; Estêvão, D.; Sánchez, D.F.; Cañete-Portillo, S.; Fernández-Nestosa, M.J.; Casaca, F.; Silva, S.; Brito, H.; Félix, A.; Medeiros, R.; Colaço, B.; Oliveira, P.A.; Bastos, M.M.S.M.; Nelson, P.S.; Vakar-Lopez, F.; Gaivão, I.; Brito, L.; Lopes, C.; Cubilla, A.L.; Gil da Costa, R.M. (2020) HPV16 induces penile intraepithelial neoplasia and squamous cell carcinoma in transgenic mice: first mouse model for HPV-related penile cancer. JOURNAL OF PATHOLOGY 251 (4) :411-419. doi: 10.1002/path.5475.. (Impact factor, Quartile: 6.021, Q1).
HPV16 is sufficient to induce squamous cell carcinoma specifically in the tongue base in transgenic mice.
Mestre, Verónica; Medeiros-Fonseca; Beatriz; Estêvão, Diogo; Casaca, Fátima; Silva, Sandra; Félix, Ana; Silva, Fernanda; Colaço, Bruno; Seixas, Fernanda; Bastos, Margarida; Lopes, Carlos; Medeiros, Rui; Oliveira, Paula A.; Gil da Costa, Rui (2020) HPV16 is sufficient to induce squamous cell carcinoma specifically in the tongue base in transgenic mice. JOURNAL OF PATHOLOGY 251 :4-11. doi: 10.1002/path.5387. (Impact factor, Quartile: 6.021, Q1).
Human papillomavirus 16-transgenic mice as a model to study cancer-associated cachexia.
da Silva, S.P.; Santos, J.M.O.; Mestre, V.F.; Medeiros-Fonseca, B.; Oliveira, P.A.; Bastos, M.M.S.M.; Gil da Costa, R.M., Medeiros, R. (2020) Human papillomavirus 16-transgenic mice as a model to study cancer-associated cachexia. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 21 (14) :5020. doi: 10.3390/ijms21145020. (Impact factor, Quartile: 4.556, Q1).
Ptaquiloside from bracken (Pteridium spp.) promotes oral carcinogenesis initiated by HPV16 in transgenic mice.
Gil Da Costa, R.M.; Neto, T.; Estêvão, D.; Moutinho, M.; Félix, A.; Medeiros, R.; Lopes, C.; Bastos, M.M.S.M.; Oliveira, P.A. (2020) Ptaquiloside from bracken (Pteridium spp.) promotes oral carcinogenesis initiated by HPV16 in transgenic mice. FOOD & FUNCTION 11 (4) :3298-3305. doi: 10.1039/d0fo00207k. (Impact factor, Quartile: 4.171, Q1).
Dietary Supplementation with the Red Seaweed Porphyra umbilicalis Protects against DNA Damage and Pre-Malignant Dysplastic Skin Lesions in HPV-Transgenic Mice.
Santos, Susana; Ferreira, Tiago; Almeida, José; Pires, Maria J.; Colaço, Aura; Lemos, Sílvia; Gil da Costa, Rui M.; Medeiros, Rui; Bastos, Margarida M.; Neuparth, Maria J.; Abreu, Helena; Pereira, Rui; Pacheco, Mário; Gaivão; Rosa, Eduardo; Oliveira, Paula A.. (2019) Dietary Supplementation with the Red Seaweed Porphyra umbilicalis Protects against DNA Damage and Pre-Malignant Dysplastic Skin Lesions in HPV-Transgenic Mice. MARINE DRUGS 17 :615. doi: 10.3390/md17110615. (Impact factor, Quartile: 3.772, Q1).
Dimethylaminoparthenolide reduces the incidence of dysplasia and ameliorates a wasting syndrome in HPV16-transgenic mice.
Santos, Joana M. O; Moreira-Pais, Alexandra; Neto, Tiago; da Silva, Sara P.; Oliveira, Paula A.; Ferreira, Rita; Mendes, Joaquim; Bastos, Margarida M.S.M; Lopes, Carlos; Casaca, Fátima; Silva, Sandra; Sweeney, Christopher; Medeiros, Rui; Gil da Costa, Rui M. (2019) Dimethylaminoparthenolide reduces the incidence of dysplasia and ameliorates a wasting syndrome in HPV16-transgenic mice. DRUG DEVELOPMENT RESEARCH 80 :824-830. doi: 10.1002/ddr.21565. (Impact factor, Quartile: 1.742, Q4).
Hallmarks of HPV carcinogenesis-The role of E6, E7 and E5 oncoproteins in cellular malignancy.
Estevão, D.; Costa, N.; Gil da Costa, R.; Medeiros, R. (2019) Hallmarks of HPV carcinogenesis-The role of E6, E7 and E5 oncoproteins in cellular malignancy. BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS 1862 (2) :153-162. doi: 10.1016/j.bbagrm.2019.01.001. (Impact factor, Quartile: 6.887, Q1).
Inhalation of bacterial cellulose nanofibrils triggers an inflammatory response and changes lung tissue morphology of mice.
Silva-Carvalho, R.; Silva, J. P.; Ferreirinha, P.; Leitão, A. F.; Andrade, F. K.; Gil da Costa, R. M.; Cristelo, C.; Rosa, M. F.; Vilanova, M.; Gama, F. M. (2019) Inhalation of bacterial cellulose nanofibrils triggers an inflammatory response and changes lung tissue morphology of mice. TOXICOLOGICAL RESEARCH 35 :45-63. doi: 10.5487/TR.2019.35.1.045. (Impact factor, Quartile: , Q2).
The Cyclooxigenase-2 Inhibitor Parecoxib Prevents Epidermal Dysplasia in HPV16-Transgenic Mice: E cacy and Safety Observations
Ferreira, Tiago; Campos, Sandra; Silva, Mónica G.; Ribeiro, Rita; Santos, Susana; Almeida, José; Pires, Maria J.; Gil da Costa, Rui M.; Córdova, Cláudia; Nogueira, António; Neuparth, Maria J.; Medeiros, Rui; Bastos, Margarida M. S.M.; Gaivão, Isabel; Peixoto, Francisco; Oliveira, Maria M.; Oliveira, Paula A. (2019) The Cyclooxigenase-2 Inhibitor Parecoxib Prevents Epidermal Dysplasia in HPV16-Transgenic Mice: E cacy and Safety Observations INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 20 :3902. doi: 10.3390/ijms20163902. (Impact factor, Quartile: 4.183, Q2).
Curcumin and Rutin Down-regulate Cyclooxygenase-2 and Reduce Tumor-associated Inflammation in HPV16-Transgenic Mice.
Moutinho, M.; Aragão, S.; Carmo, D.; Casaca, F.; Silva, S.; Ribeiro, J.; Sousa, H.; Pires, I.; Queiroga, F.; Colaço, B.; Medeiros, R.; Oliveira, P.A.; Lopes, C.; Bastos, M.; Gil da Costa, R. (2018) Curcumin and Rutin Down-regulate Cyclooxygenase-2 and Reduce Tumor-associated Inflammation in HPV16-Transgenic Mice. Anticancer Research 38 :1461-1466. doi: 10.21873/anticanres.12371. (Impact factor, Quartile: 1.865, Q4).
Dysregulation of cellular microRNAs by human oncogenic viruses - Implications for tumorigenesis.
Santos, Joana M. O.; Gil da Costa, Rui M.; Medeiros, Rui (2018) Dysregulation of cellular microRNAs by human oncogenic viruses - Implications for tumorigenesis. Biochimica Et Biophysica Acta-Gene Regulatory Mechanisms 1861 (2) :95-105. doi: 10.1016/j.bbagrm.2018.01.017. (Impact factor, Quartile: 5.179, Q1).
Expression profile of microRNA-146a along HPV-induced multistep carcinogenesis: a study in HPV16 transgenic mice.
Araujo, Rita; Santos, Joana M. O.; Fernandes, Mara; Dias, Francisca; Sousa, Hugo; Ribeiro, Joana; Bastos, Margarida M. S. M.; Oliveira, Paula A.; Carmo, Diogo; Casaca, Fatima; Silva, Sandra; Medeiros, Rui; Gil da Costa, Rui M. (2018) Expression profile of microRNA-146a along HPV-induced multistep carcinogenesis: a study in HPV16 transgenic mice. Journal Of Cancer Research And Clinical Oncology 144 (2) :241:248. doi: 10.1007/s00432-017-2549-5. (Impact factor, Quartile: 3.282, Q2).
Laurus nobilis (laurel) aqueous leaf extract's toxicological and anti-tumor activities in HPV16-transgenic mice.
Medeiros-Fonseca, B; Mestre, VF; Colaço, B; Pires, MJ; Martins, T; Gil da Costa, RM; Neuparth, MJ; Medeiros, R; Moutinho, MSS; Dias, MI; Barros, L; Bastos, MMSM; Félix, L; Venâncio, C; Ferreira, ICFR; Antunes, LM; Oliveira, PA. (2018) Laurus nobilis (laurel) aqueous leaf extract's toxicological and anti-tumor activities in HPV16-transgenic mice. FOOD & FUNCTION 9 :4419-4428. doi: 10.1039/c8fo00783g. (Impact factor, Quartile: 3.289, Q1).
Ozone therapy prevents the onset of dysplasia in HPV16-transgenic mice-A pre-clinical efficacy and safety analysis.
Peirone, C.; Mestre, V. F.; Medeiros-Fonseca, B.; Colaço, B.; Pires, M. J.; Martins, T.; Gil da Costa, R. M.; Neuparth, M. J.; Medeiros, R.; Bastos, M. M. S. M.; Marques-Magallanes, J. A.; Oliveira, P. A. (2018) Ozone therapy prevents the onset of dysplasia in HPV16-transgenic mice-A pre-clinical efficacy and safety analysis. Biomedicine & Pharmacotherapy 104 :275-279. doi: 10.1016/j.biopha.2018.05.018. (Impact factor, Quartile: 3.457, Q2).
Platinum-induced muscle wasting in cancer chemotherapy: Mechanisms and potential targets for therapeutic intervention.
Moreira-Pais, Alexandra; Ferreira, Rita; da Costa, Rui Gil (2018) Platinum-induced muscle wasting in cancer chemotherapy: Mechanisms and potential targets for therapeutic intervention. Life Sciences 208 :43344. doi: 10.1016/j.lfs.2018.07.010. (Impact factor, Quartile: 3.234, Q2).
Quantitative assessment of DNA damage in the industrial ethanol production strain Saccharomyces cerevisiae PE-2.
Silva, Paulo C,; Domingues, Lucilia; Collins, Tony; Oliveira, Rui; Johansson, Björn (2018) Quantitative assessment of DNA damage in the industrial ethanol production strain Saccharomyces cerevisiae PE-2. FEMS YEAST RESEARCH 18 (8) :foy101. doi: 10.1093/femsyr/foy101. (Impact factor, Quartile: 2.609, Q2).
HPV16 induces a wasting syndrome in transgenic mice: Amelioration by dietary polyphenols via NF-kappa B inhibition.
da Costa, RMG, Aragao, S, Moutinho, M, Alvarado, A, Carmo, D, Casaca, F, Silva, S, Ribeiro, J, Sousa, H, Ferreira, R, Nogueira-Ferreira, R, Pires, MJ, Colaço, B, Medeiros, R, Venancio, C, Oliveira, MM, Bastos, MMSM, Lopes, C, Oliveira, PA (2017) HPV16 induces a wasting syndrome in transgenic mice: Amelioration by dietary polyphenols via NF-kappa B inhibition. Life Sciences 169 :19-Nov. ISSN: 0024-3205. doi: 10.1016/j.lfs.2016.10.031. (Impact factor, Quartile: 2.963, Q2).
Regulation of miRNA-146a and miRNA-150 Levels by Celecoxib in Premalignant Lesions of K14-HPV16 Mice.
Da Costa, RMG, Araujo, R, Santos, JMO, Fernandes, M, Neto, T, Sousa, H, Ribeiro, J, Bastos, MMSM, Oliveira, PA, Carmo, D, Casaca, F, Silva, S, Lopes, C, Medeiros, R (2017) Regulation of miRNA-146a and miRNA-150 Levels by Celecoxib in Premalignant Lesions of K14-HPV16 Mice. Anticancer Research 37 :2913-2918. ISSN: 0250-7005. doi: 10.21873/anticanres.11644. (Impact factor, Quartile: 1.937, Q3).