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Luís Miguel Joaquim Marques Antunes Integrated Member

BIO

Name: Luís Miguel Joaquim Marques Antunes

Aggregation: Integrated Member

Scopus author ID: 57204821163

Orcid ID: 0000-0002-9757-6879

Ciência Vitae: DA1A-814B-FBF3

Email: lantunes@utad.pt

Research Groups

Resiliency & valorisation of agrarian value chains

Publications

Early developmental effects of propofol exposure in different stages of zebrafish embryos
Félix L., Campos S., Guedes de Pinho P., Antunes L., Valentim A.M., (2025) Early developmental effects of propofol exposure in different stages of zebrafish embryos Toxicology Letters 403 :84-93. ISSN: 18793169. doi: 10.1016/j.toxlet.2024.12.002.
Lidocaine supplementation in clove-oil and 2-phenoxyethanol anesthesia for gilthead seabream (Sparus aurata)
Tchobanov C.F., Vaz M., Pires D., Passos R., Antunes L.M., Baptista T., (2024) Lidocaine supplementation in clove-oil and 2-phenoxyethanol anesthesia for gilthead seabream (Sparus aurata) Aquaculture Reports 37 (102224). ISSN: 23525134. doi: 10.1016/j.aqrep.2024.102224.
Anesthesia, restraint and analgesia in laboratory fishes
Köhler A., Finger-Baier K., Antunes L., (2023) Anesthesia, restraint and analgesia in laboratory fishes Anesthesia and Analgesia in Laboratory Animals :393-409. doi: 10.1016/B978-0-12-822215-7.00001-9.
Brassica oleracea Var italica by-Products Prevent Lipid Accumulation and Cell Death in a Liver Cell Model of Lipid Toxicity
Castelão-Baptista J.P., Valente S.A., Canário S., Oppolzer D., Barros A., Venâncio C., Martins T., Antunes L., Sardão V.A., Rosa E., Oliveira P.J., (2023) Brassica oleracea Var italica by-Products Prevent Lipid Accumulation and Cell Death in a Liver Cell Model of Lipid Toxicity Nutrients 15 (924). ISSN: 20726643. doi: 10.3390/nu15040924.
Enhancing Health Benefits through Chlorophylls and Chlorophyll-Rich Agro-Food: A Comprehensive Review
Martins T., Barros A.N., Rosa E., Antunes L., (2023) Enhancing Health Benefits through Chlorophylls and Chlorophyll-Rich Agro-Food: A Comprehensive Review Molecules 28 (5344). ISSN: 14203049. doi: 10.3390/molecules28145344.
Beneficial Effects of Broccoli (Brassica oleracea var italica) By-products in Diet-induced Obese Mice
Martins T., Leite R., Matos A.F., Soares J., Pires M.J., de Lurdes Pinto M., Neuparth M.J., Sequeira A.R., Félix L., Venâncio C., Monteiro S.M., Colaço B., Gouvinhas I., Barros A.I., Rosa E., Oliveira P.A., Antunes L.M., (2022) Beneficial Effects of Broccoli (Brassica oleracea var italica) By-products in Diet-induced Obese Mice In Vivo 36 :2173-2185. ISSN: 17917549. doi: 10.21873/invivo.12943.
Comparison of Gelatin Flavors for Oral Dosing of C57BL/6J and FVB/N Mice
Martins T., Matos A.F., Soares J., Leite R., Pires M.J., Ferreira T., Medeiros-Fonseca B., Rosa E., Oliveira P.A., Antunes L.M., (2022) Comparison of Gelatin Flavors for Oral Dosing of C57BL/6J and FVB/N Mice Journal of the American Association for Laboratory Animal Science 61 :89-95. doi: 10.30802/AALAS-JAALAS-21-000045.
Effect of a Sub-Chronic Oral Exposure of Broccoli (Brassica oleracea L. Var. Italica) By-Products Flour on the Physiological Parameters of FVB/N Mice: A Pilot Study
Martins T., Oliveira P.A., Pires M.J., Neuparth M.J., Lanzarin G., Félix L., Venâncio C., Pinto M.d.L., Ferreira J., Gaivão I., Barros A.I., Rosa E., Antunes L.M., (2022) Effect of a Sub-Chronic Oral Exposure of Broccoli (Brassica oleracea L. Var. Italica) By-Products Flour on the Physiological Parameters of FVB/N Mice: A Pilot Study Foods 11 (120). ISSN: 23048158. doi: 10.3390/foods11010120.
Malformations and mortality in zebrafish early stages associated with elevated caspase activity after 24 h exposure to MS-222
Félix L.M., Luzio A., Antunes L., Coimbra A.M., Valentim A.M., (2021) Malformations and mortality in zebrafish early stages associated with elevated caspase activity after 24 h exposure to MS-222 Toxicology and Applied Pharmacology 412 (115385). ISSN: 10960333. doi: 10.1016/j.taap.2020.115385.
Ms-222 and propofol sedation during and after the simulated transport of nile tilapia (Oreochromis niloticus)
Félix L., Correia R., Sequeira R., Ribeiro C., Monteiro S., Antunes L., Silva J., Venâncio C., Valentim A., (2021) Ms-222 and propofol sedation during and after the simulated transport of nile tilapia (Oreochromis niloticus) Biology 10 (1309). ISSN: 20797737. doi: 10.3390/biology10121309.
Refinement of animal model of colorectal carcinogenesis through the definition of novel humane endpoints
Silva-Reis R., Faustino-Rocha A.I., Gonçalves M., Ribeiro C.C., Ferreira T., Ribeiro-Silva C., Gonçalves L., Antunes L., Venâncio C., Ferreira R., Gama A., Oliveira P.A., (2021) Refinement of animal model of colorectal carcinogenesis through the definition of novel humane endpoints Animals 11 (985). ISSN: 20762615. doi: 10.3390/ani11040985.
MS-222 induces biochemical and transcriptional changes related to oxidative stress, cell proliferation and apoptosis in zebrafish embryos
Félix L.M., Luzio A., Santos A., Antunes L.M., Coimbra A.M., Valentim A.M., (2020) MS-222 induces biochemical and transcriptional changes related to oxidative stress, cell proliferation and apoptosis in zebrafish embryos Comparative Biochemistry and Physiology Part - C: Toxicology and Pharmacology 237 (108834). ISSN: 18781659. doi: 10.1016/j.cbpc.2020.108834.
Anaesthetics and analgesics used in adult fish for research: A review
Martins T., Valentim A., Pereira N., Antunes L.M., (2019) Anaesthetics and analgesics used in adult fish for research: A review Laboratory Animals 53 :325-341. ISSN: 17581117. doi: 10.1177/0023677218815199.
Parasympathetic Tone Activity Evaluation to Discriminate Ketorolac and Ketorolac/Tramadol Analgesia Level in Swine
Leitaõ C.J., Lima-Rodríguez J.R., Ferreira F., Avelino C., Sánchez-Margallo F.M., Antunes L., (2019) Parasympathetic Tone Activity Evaluation to Discriminate Ketorolac and Ketorolac/Tramadol Analgesia Level in Swine Anesthesia and Analgesia 129 :882-889. ISSN: 15267598. doi: 10.1213/ANE.0000000000003573.
Review on the use of zebrafish embryos to study the effects of anesthetics during early development
Félix L., Coimbra A.M., Valentim A.M., Antunes L., (2019) Review on the use of zebrafish embryos to study the effects of anesthetics during early development Critical Reviews in Toxicology 49 :357-370. ISSN: 15476898. doi: 10.1080/10408444.2019.1617236.
Evaluation of anaesthetic protocols for laboratory adult zebrafish(Danio rerio).
Martins, Tania; Diniz, Enoque; Felix, Luis M.; Antunes, Luis (2018) Evaluation of anaesthetic protocols for laboratory adult zebrafish(Danio rerio). Plos One 13 (5). doi: 10.1371/journal.pone.0197846. (Impact factor, Quartile: 2.766, Q1).
Ketamine induction of p53-dependent apoptosis and oxidative stress in zebrafish (Danio rerio) embryos.
Felix, Luis M.; Vidal, Ana M.; Serafim, Cindy; Valentim, Ana M.; Antunes, Luis M.; Monteiro, Sandra M.; Matos, Manuela; Coimbra, Ana M. (2018) Ketamine induction of p53-dependent apoptosis and oxidative stress in zebrafish (Danio rerio) embryos. Chemosphere 201 :730-739. doi: 10.1016/j.chemosphere.2018.03.049. (Impact factor, Quartile: 4.427, Q1).
Laurus nobilis (laurel) aqueous leaf extract's toxicological and anti-tumor activities in HPV16-transgenic mice.
Medeiros-Fonseca, B; Mestre, VF; Colaço, B; Pires, MJ; Martins, T; Gil da Costa, RM; Neuparth, MJ; Medeiros, R; Moutinho, MSS; Dias, MI; Barros, L; Bastos, MMSM; Félix, L; Venâncio, C; Ferreira, ICFR; Antunes, LM; Oliveira, PA. (2018) Laurus nobilis (laurel) aqueous leaf extract's toxicological and anti-tumor activities in HPV16-transgenic mice. FOOD & FUNCTION 9 :4419-4428. doi: 10.1039/c8fo00783g. (Impact factor, Quartile: 3.289, Q1).
MS-222 short exposure induces developmental and behavioural alterations in zebrafish embryos.
Felix, L.M.; Luzio, A.; Themudo, M.; Antunes, L.; Matos, M.; Coimbra, A.M.; Valentim, A.M. (2018) MS-222 short exposure induces developmental and behavioural alterations in zebrafish embryos. Reproductive Toxicology 81 :122-131. doi: 10.1016/j.reprotox.2018.07.086. (Impact factor, Quartile: 2.58, Q2).
Potential effects of sulforaphane to fight obesity.
Martins, Tânia; Colaço, Bruno; Venâncio, Carlos; Pires, Maria J.; Oliveira, Paula A.; Rosa, Eduardo; Antunes, Luis M. (2018) Potential effects of sulforaphane to fight obesity. Journal Of The Science Of Food And Agriculture 98 (8) :2837-2844. doi: 10.1002/jsfa.8898. (Impact factor, Quartile: 2.379, Q1).
Apoptosis-related genes induced in response to ketamine during early life stages of zebrafish.
Felix, LM, Serafim, C, Valentim, AM, Antunes, LM, Matos, M, Coimbra, AM (2017) Apoptosis-related genes induced in response to ketamine during early life stages of zebrafish. Toxicology Letters 279 :8-Jan. ISSN: 0378-4274. doi: 10.1016/j.toxlet.2017.07.888. (Impact factor, Quartile: 3.858, Q1).
Behavioral alterations of zebrafish larvae after early embryonic exposure to ketamine.
Felix, LM, Antunes, LM, Coimbra, AM, Valentim, AM (2017) Behavioral alterations of zebrafish larvae after early embryonic exposure to ketamine. Psychopharmacology 234 :549-558. ISSN: 0033-3158. doi: 10.1007/s00213-016-4491-7. (Impact factor, Quartile: 3.308, Q2).
Implementation of Human Endpoints in a Urinary Bladder Carcinogenesis Study in Rats.
Oliveira, M, Nascimento-Goncalves, E, Silva, J, Oliveira, PA, Ferreira, R, Antunes, L, Arantes-Rodrigues, R, Faustino-Rocha, AI (2017) Implementation of Human Endpoints in a Urinary Bladder Carcinogenesis Study in Rats. In Vivo 31 :1073-1080. ISSN: 0258-851X. doi: 10.21873/invivo.11172. (Impact factor, Quartile: 0.953, Q4).
Morphological and behavioral responses of zebrafish after 24h of ketamine embryonic exposure.
Felix, LM, Serafim, C, Martins, MJ, Valentim, AM, Antunes, LM, Matos, M, Coimbra, AM (2017) Morphological and behavioral responses of zebrafish after 24h of ketamine embryonic exposure. Toxicology And Applied Pharmacology 321 :27-36. ISSN: 0041-008X. doi: 10.1016/j.taap.2017.02.013. (Impact factor, Quartile: 3.791, Q1).
Propofol affinity to mitochondrial membranes does not alter mitochondrial function.
Felix, LM, Correia, F, Pinto, PA, Campos, SP, Fernandes, T, Videira, R, Oliveira, MM, Peixoto, FP, Antunes, LM (2017) Propofol affinity to mitochondrial membranes does not alter mitochondrial function. European Journal Of Pharmacology 803 :48-56. ISSN: 0014-2999. doi: 10.1016/j.ejphar.2017.03.044. (Impact factor, Quartile: 2.896, Q2).

Projects

ZEBREFINE: Optimization of anesthesia in zebrafish: economic, clinical and animal welfare implications
Concluded

Coordinator  /  Ana Maria Marques Valentim UTAD/CITAB Coordinator  /  Luís Antunes
Start date  /  2018/07 Funding  /  FCT/FEDER Reference  /  POCI-01-0145-FEDER-029542

See project details →

VALORIZEBYPRODUCTS: Preclinical efficacy of sulforaphane or Brassica whole extract: a strategy to fight obesity and valorize Brassica byproduct
Concluded

Coordinator  /  Eduardo Rosa
Start date  /  2018/06 Funding  /  FCT/FEDER Reference  /  POCI-01-0145-FEDER-029152

See project details →