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Luís Manuel Lourenço Félix PhD Collaborator

BIO

Name: Luís Manuel Lourenço Félix

Aggregation: PhD Collaborator

Scopus author ID:

Orcid ID: 0000-0001-9870-6666

Email: lfelix@utad.pt

Research Tasks

Integrated monitoring of climate and environmental impacts

Publications

Effect of a Sub-Chronic Oral Exposure of Broccoli (Brassica oleracea L. Var. Italica) By-Products Flour on the Physiological Parameters of FVB/N Mice: A Pilot Study.
Martins, T. ; Oliveira, P.O. ; Pires, M.J. ; Neuparth, M.J. ; Lanzarin, G. ; Félix, L. ; Venâncio, C. ; Pinto, M.L. ; Ferreira, J. ; Gaivão, I. ; Barros. A.I. ; Rosa, E. ; Antunes L.M. (2022) Effect of a Sub-Chronic Oral Exposure of Broccoli (Brassica oleracea L. Var. Italica) By-Products Flour on the Physiological Parameters of FVB/N Mice: A Pilot Study. Foods 11 (120). doi: 10.3390/foods11010120. (Impact factor, Quartile: 4.350, Q2).
Malformations and mortality in zebrafish early stages associated with elevated caspase activity after 24 h exposure to MS-222.
Félix, L.M., Luzio, A. , Antunes, L. , Coimbra, A.C. , Valentim, A.M. (2021) Malformations and mortality in zebrafish early stages associated with elevated caspase activity after 24 h exposure to MS-222. Toxicology and Applied Pharmacology (412) :115385. doi: 10.1016/j.taap.2020.115385. (Impact factor, Quartile: 4.219, Q2).
Multi-Biomarker Responses of Asian Clam Corbicula fluminea (Bivalvia, Corbiculidea) to Cadmium and Microplastics Pollutants.
Parra, S. ; Varandas, S. ; Santos, D. ; Félix, L. ; Fernandes, L. ; Cabecinha, E. ; Gago, J. ; Monteiro, S. (2021) Multi-Biomarker Responses of Asian Clam Corbicula fluminea (Bivalvia, Corbiculidea) to Cadmium and Microplastics Pollutants. Water 13 (4), 394. doi: 10.3390/w13040394. (Impact factor, Quartile: 3.103, Q2).
Orange thyme: Phytochemical profiling, in vitro bioactivities of extracts and potential health benefits.
Silva, A.M. ; Felix, L.M. ; Teixeira, I. ; Martins-Gomes, C. ; Schafer, J. ; Souto, E.B. ; Santos, D.J. ; Bunzel, M. ; Nunes, F.M. (2021) Orange thyme: Phytochemical profiling, in vitro bioactivities of extracts and potential health benefits. Food Chemistry X (12) :100127. doi: 10.1016/j.fochx.2021.100171. (Impact factor, Quartile: 7.514, Q1).
24-Epibrassinolide protects against ethanol-induced behavioural teratogenesis in zebrafish embryo.
Fernandes, P.; Monteiro, S.M.; Venâncio, C.; Félix L. ( (2020) 24-Epibrassinolide protects against ethanol-induced behavioural teratogenesis in zebrafish embryo. CHEMICAL-BIOLOGICAL INTERACTIONS 328 :109193. doi: 10.1016/j.cbi.2020.109193. (Impact factor, Quartile: 3.723, Q1).
Behavioural toxicity of environmental relevant concentrations of a glyphosate commercial formulation - RoundUp® UltraMax - During zebrafish embryogenesis.
Lanzarin, G.A.B.; Venâncio, C.A.S.; Monteiro, S.M.; Félix, L.M. (2020) Behavioural toxicity of environmental relevant concentrations of a glyphosate commercial formulation - RoundUp® UltraMax - During zebrafish embryogenesis. CHEMOSPHERE 253 :126636. doi: 10.1016/j.chemosphere.2020.126636. (Impact factor, Quartile: 5.778, Q1).
Dietary supplementation with chestnut (Castanea sativa) reduces abdominal adiposity in FVB/n mice: A preliminary study.
Rodrigues, P.; Ferreira, T.; Nascimento-Gonçalves, E.; Seixas, F.; Gil da Costa, R.M.; Martins, T.; Neuparth, M.J.; Pires, M.J.; Lanzarin, G.; Félix, L.; Venâncio, C.; Ferreira, I.C.F.R.; Bastos, M.M.S.M.; Medeiros, R.; Gaivão, I.; Rosa, E.; Oliveira, P.A. (2020) Dietary supplementation with chestnut (Castanea sativa) reduces abdominal adiposity in FVB/n mice: A preliminary study. BIOMEDICINES 8 (4) :75. doi: 10.3390/biomedicines8040075. (Impact factor, Quartile: 4.717, Q1).
MS-222 induces biochemical and transcriptional changes related to oxidative stress, cell proliferation and apoptosis in zebrafish embryos.
Félix, Luís M.; Luzio, Ana; Santos, Ana; Antunes, Luís M.; Coimbra, Ana M.; Valentim, Ana M. (2020) MS-222 induces biochemical and transcriptional changes related to oxidative stress, cell proliferation and apoptosis in zebrafish embryos. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY, PART C 237 :108834. doi: 10.1016/j.cbpc.2020.108834. (Impact factor, Quartile: 2.033, Q3).
Polyphenol composition and biological activity of Thymus citriodorus and Thymus vulgaris: Comparison with endemic Iberian Thymus species.
Taghouti, M.; Martins-Gomes, C.; Félix, L.M.; Schäfer, J.; Santos, J.A.; Bunzel, M.; Nunes, F.M.; Silva, A.M. (2020) Polyphenol composition and biological activity of Thymus citriodorus and Thymus vulgaris: Comparison with endemic Iberian Thymus species. FOOD CHEMISTRY 331 :127362. doi: 10.1016/j.foodchem.2020.127362. (Impact factor, Quartile: 6.306, Q1).
Toxic effects of a mancozeb-containing commercial formulation at environmental relevant concentrations on zebrafish embryonic development
Vieira, R.; Venâncio, C.A.S.; Félix, L.M. (2020) Toxic effects of a mancozeb-containing commercial formulation at environmental relevant concentrations on zebrafish embryonic development ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH 27 (17) :21174-21187. doi: 10.1007/s11356-020-08412-0. (Impact factor, Quartile: 3.056, Q2).
Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper.
Santos, D.; Félix, L.; Luzio, A.; Parra, S.; Cabecinha, E.; Bellas J.; Monteiro, S.M. (2020) Toxicological effects induced on early life stages of zebrafish (Danio rerio) after an acute exposure to microplastics alone or co-exposed with copper. CHEMOSPHERE 261 :127748. doi: 10.1016/j.chemosphere.2020.127748. (Impact factor, Quartile: 5.778, Q1).
Dose-dependent effects of a glyphosate commercial formulation e Roundup® UltraMax - on the early zebrafish embryogenesis.
Lanzarin, Germano A.B.; Félix, Luís, M.; Santos, Dércia; Venâncio, Carlos A.S.; Monteiro, Sandra M. (2019) Dose-dependent effects of a glyphosate commercial formulation e Roundup® UltraMax - on the early zebrafish embryogenesis. CHEMOSPHERE 223 :514-522. doi: 10.1016/j.chemosphere.2019.02.071. (Impact factor, Quartile: 5.108, Q1).
Review on the use of zebrafish embryos to study the effects of anesthetics during early development.
Félix, Luís; Coimbra, Ana M.; Valentim, Ana M.; Antunes, Luís (2019) Review on the use of zebrafish embryos to study the effects of anesthetics during early development. CRITICAL REVIEWS IN TOXICOLOGY 49 (4) :357-370. doi: 10.1080/10408444.2019.1617236. (Impact factor, Quartile: 4.771, Q1).
Evaluation of anaesthetic protocols for laboratory adult zebrafish(Danio rerio).
Martins, Tania; Diniz, Enoque; Felix, Luis M.; Antunes, Luis (2018) Evaluation of anaesthetic protocols for laboratory adult zebrafish(Danio rerio). Plos One 13 (5). doi: 10.1371/journal.pone.0197846. (Impact factor, Quartile: 2.766, Q1).
Ketamine induction of p53-dependent apoptosis and oxidative stress in zebrafish (Danio rerio) embryos.
Felix, Luis M.; Vidal, Ana M.; Serafim, Cindy; Valentim, Ana M.; Antunes, Luis M.; Monteiro, Sandra M.; Matos, Manuela; Coimbra, Ana M. (2018) Ketamine induction of p53-dependent apoptosis and oxidative stress in zebrafish (Danio rerio) embryos. Chemosphere 201 :730-739. doi: 10.1016/j.chemosphere.2018.03.049. (Impact factor, Quartile: 4.427, Q1).
Laurus nobilis (laurel) aqueous leaf extract's toxicological and anti-tumor activities in HPV16-transgenic mice.
Medeiros-Fonseca, B; Mestre, VF; Colaço, B; Pires, MJ; Martins, T; Gil da Costa, RM; Neuparth, MJ; Medeiros, R; Moutinho, MSS; Dias, MI; Barros, L; Bastos, MMSM; Félix, L; Venâncio, C; Ferreira, ICFR; Antunes, LM; Oliveira, PA. (2018) Laurus nobilis (laurel) aqueous leaf extract's toxicological and anti-tumor activities in HPV16-transgenic mice. FOOD & FUNCTION 9 :4419-4428. doi: 10.1039/c8fo00783g. (Impact factor, Quartile: 3.289, Q1).
MS-222 short exposure induces developmental and behavioural alterations in zebrafish embryos.
Felix, L.M.; Luzio, A.; Themudo, M.; Antunes, L.; Matos, M.; Coimbra, A.M.; Valentim, A.M. (2018) MS-222 short exposure induces developmental and behavioural alterations in zebrafish embryos. Reproductive Toxicology 81 :122-131. doi: 10.1016/j.reprotox.2018.07.086. (Impact factor, Quartile: 2.58, Q2).
Thymus pulegioides L. as a rich source of antioxidant, anti-proliferative and neuroprotective phenolic compounds.
Taghouti, Meriem; Martins-Gomes, Carlos; Schaefer, Judith; Felix, Luis M.; Santos, Joao A.; Bunzel, Mirko; Nunes, Fernando M.; Silva, Amelia M. (2018) Thymus pulegioides L. as a rich source of antioxidant, anti-proliferative and neuroprotective phenolic compounds. Food & Function 9 (7) :3617-3629. doi: 10.1039/c8fo00456k. (Impact factor, Quartile: 3.289, Q1).
Apoptosis-related genes induced in response to ketamine during early life stages of zebrafish.
Felix, LM, Serafim, C, Valentim, AM, Antunes, LM, Matos, M, Coimbra, AM (2017) Apoptosis-related genes induced in response to ketamine during early life stages of zebrafish. Toxicology Letters 279 :8-Jan. ISSN: 0378-4274. doi: 10.1016/j.toxlet.2017.07.888. (Impact factor, Quartile: 3.858, Q1).
Behavioral alterations of zebrafish larvae after early embryonic exposure to ketamine.
Felix, LM, Antunes, LM, Coimbra, AM, Valentim, AM (2017) Behavioral alterations of zebrafish larvae after early embryonic exposure to ketamine. Psychopharmacology 234 :549-558. ISSN: 0033-3158. doi: 10.1007/s00213-016-4491-7. (Impact factor, Quartile: 3.308, Q2).
Carvedilol exacerbate gentamicin-induced kidney mitochondrial alterations in adult rat.
Felix, L, Oliveira, MM, Videira, R, Maciel, E, Alves, ND, Nunes, FM, Alves, A, Almeida, JM, Domingues, MRM, Peixoto, FP (2017) Carvedilol exacerbate gentamicin-induced kidney mitochondrial alterations in adult rat. Experimental And Toxicologic Pathology 69 :83-92. ISSN: 0940-2993. doi: 10.1016/j.etp.2016.11.006. (Impact factor, Quartile: 1.975, Q2).
Morphological and behavioral responses of zebrafish after 24h of ketamine embryonic exposure.
Felix, LM, Serafim, C, Martins, MJ, Valentim, AM, Antunes, LM, Matos, M, Coimbra, AM (2017) Morphological and behavioral responses of zebrafish after 24h of ketamine embryonic exposure. Toxicology And Applied Pharmacology 321 :27-36. ISSN: 0041-008X. doi: 10.1016/j.taap.2017.02.013. (Impact factor, Quartile: 3.791, Q1).
Propofol affinity to mitochondrial membranes does not alter mitochondrial function.
Felix, LM, Correia, F, Pinto, PA, Campos, SP, Fernandes, T, Videira, R, Oliveira, MM, Peixoto, FP, Antunes, LM (2017) Propofol affinity to mitochondrial membranes does not alter mitochondrial function. European Journal Of Pharmacology 803 :48-56. ISSN: 0014-2999. doi: 10.1016/j.ejphar.2017.03.044. (Impact factor, Quartile: 2.896, Q2).

Projects

ZEBREFINE: Optimization of anesthesia in zebrafish: economic, clinical and animal welfare implications
Concluded

Coordinator  /  Ana Maria Marques Valentim UTAD/CITAB Coordinator  /  Luís Antunes
Start date  /  2018/07 Funding  /  FCT/FEDER Reference  /  POCI-01-0145-FEDER-029542

See project details →

Zebrafish (Danio rerio) anaesthesia and potential implications in research – reduction, replacement and refining
Concluded

Coordinator  /  Ana Maria Marques Valentim UTAD/CITAB Coordinator  /  Sandra Monteiro
Start date  /  2013/07 Funding  /  FCT Reference  /  PTDC/CVT-WEL/4672/2012

See project details →