Ana Maria Monteiro Paiva Coimbra Integrated Member

BIO

Name: Ana Maria Monteiro Paiva Coimbra

Aggregation: Integrated Member

Scopus author ID: 8941623700

Orcid ID: 0000-0003-3110-7153

Ciência Vitae: 651C-72CD-04AA

Email: acoimbra@utad.pt

Start date: 01-04-2008

Publications

Are Fish Populations at Risk? Metformin Disrupts Zebrafish Development and Reproductive Processes at Chronic Environmentally Relevant Concentrations
Barros S., Alves N., Pinheiro M., Ribeiro M., Morais H., Montes R., Rodil R., Quintana J.B., Coimbra A.M., Santos M.M., Neuparth T., (2023) Are Fish Populations at Risk? Metformin Disrupts Zebrafish Development and Reproductive Processes at Chronic Environmentally Relevant Concentrations Environmental Science and Technology 57 :1049-1059. ISSN: 15205851. doi: 10.1021/acs.est.2c05719.

Metformin disrupts Danio rerio metabolism at environmentally relevant concentrations: A full life-cycle study
Barros S., Ribeiro M., Coimbra A.M., Pinheiro M., Morais H., Alves N., Montes R., Rodil R., Quintana J.B., Santos M.M., Neuparth T., (2022) Metformin disrupts Danio rerio metabolism at environmentally relevant concentrations: A full life-cycle study Science of the Total Environment 846 (157361). ISSN: 18791026. doi: 10.1016/j.scitotenv.2022.157361.

Effects of short-term exposure to genistein and overfeeding diet on the neural and retinal progenitor competence of adult zebrafish (Danio rerio)
Luzio A., Figueiredo M., Matos M.M., Coimbra A.M., Álvaro A.R., Monteiro S.M., (2021) Effects of short-term exposure to genistein and overfeeding diet on the neural and retinal progenitor competence of adult zebrafish (Danio rerio) Neurotoxicology and Teratology 88 (107030). ISSN: 18729738. doi: 10.1016/j.ntt.2021.107030.

Malformations and mortality in zebrafish early stages associated with elevated caspase activity after 24 h exposure to MS-222
Félix L.M., Luzio A., Antunes L., Coimbra A.M., Valentim A.M., (2021) Malformations and mortality in zebrafish early stages associated with elevated caspase activity after 24 h exposure to MS-222 Toxicology and Applied Pharmacology 412 (115385). ISSN: 10960333. doi: 10.1016/j.taap.2020.115385.

Zebrafish male differentiation: Do all testes go through a “juvenile ovary” stage?
Luzio A., Santos D., Monteiro S.M., Coimbra A.M., (2021) Zebrafish male differentiation: Do all testes go through a “juvenile ovary” stage? Tissue and Cell 72 (101545). ISSN: 15323072. doi: 10.1016/j.tice.2021.101545.

Chronic exposure to environmentally relevant levels of simvastatin disrupts zebrafish brain gene signaling involved in energy metabolism
Barros S., Coimbra A.M., Alves N., Pinheiro M., Quintana J.B., Santos M.M., Neuparth T., (2020) Chronic exposure to environmentally relevant levels of simvastatin disrupts zebrafish brain gene signaling involved in energy metabolism Journal of Toxicology and Environmental Health - Part A: Current Issues 83 :113-125. ISSN: 10872620. doi: 10.1080/15287394.2020.1733722.

MS-222 induces biochemical and transcriptional changes related to oxidative stress, cell proliferation and apoptosis in zebrafish embryos
Félix L.M., Luzio A., Santos A., Antunes L.M., Coimbra A.M., Valentim A.M., (2020) MS-222 induces biochemical and transcriptional changes related to oxidative stress, cell proliferation and apoptosis in zebrafish embryos Comparative Biochemistry and Physiology Part - C: Toxicology and Pharmacology 237 (108834). ISSN: 18781659. doi: 10.1016/j.cbpc.2020.108834.

A gill histopathology study in two native fish species from the hydrographic douro basin
Santos D., Luzio A., Coimbra A.M., Varandas S., Fontaínhas-Fernandes A., Monteiro S.M., (2019) A gill histopathology study in two native fish species from the hydrographic douro basin Microscopy and Microanalysis 25 :236-243. ISSN: 14358115. doi: 10.1017/S1431927618015490.

Hazardous impact of vinasse from distilled winemaking by-products in terrestrial plants and aquatic organisms
Sousa R., Amaral C., Fernandes J., Fraga I., Semitela S., Braga F., Coimbra A., Dias A., Bezerra R., Sampaio A., (2019) Hazardous impact of vinasse from distilled winemaking by-products in terrestrial plants and aquatic organisms Ecotoxicology and Environmental Safety 183 (109493). ISSN: 10902414. doi: 10.1016/j.ecoenv.2019.109493.

Review on the use of zebrafish embryos to study the effects of anesthetics during early development
Félix L., Coimbra A.M., Valentim A.M., Antunes L., (2019) Review on the use of zebrafish embryos to study the effects of anesthetics during early development Critical Reviews in Toxicology 49 :357-370. ISSN: 15476898. doi: 10.1080/10408444.2019.1617236.

Ketamine induction of p53-dependent apoptosis and oxidative stress in zebrafish (Danio rerio) embryos.
Felix, Luis M.; Vidal, Ana M.; Serafim, Cindy; Valentim, Ana M.; Antunes, Luis M.; Monteiro, Sandra M.; Matos, Manuela; Coimbra, Ana M. (2018) Ketamine induction of p53-dependent apoptosis and oxidative stress in zebrafish (Danio rerio) embryos. Chemosphere 201 :730-739. doi: 10.1016/j.chemosphere.2018.03.049. (Impact factor, Quartile: 4.427, Q1).

MS-222 short exposure induces developmental and behavioural alterations in zebrafish embryos.
Felix, L.M.; Luzio, A.; Themudo, M.; Antunes, L.; Matos, M.; Coimbra, A.M.; Valentim, A.M. (2018) MS-222 short exposure induces developmental and behavioural alterations in zebrafish embryos. Reproductive Toxicology 81 :122-131. doi: 10.1016/j.reprotox.2018.07.086. (Impact factor, Quartile: 2.58, Q2).

Apoptosis-related genes induced in response to ketamine during early life stages of zebrafish.
Felix, LM, Serafim, C, Valentim, AM, Antunes, LM, Matos, M, Coimbra, AM (2017) Apoptosis-related genes induced in response to ketamine during early life stages of zebrafish. Toxicology Letters 279 :8-Jan. ISSN: 0378-4274. doi: 10.1016/j.toxlet.2017.07.888. (Impact factor, Quartile: 3.858, Q1).

Behavioral alterations of zebrafish larvae after early embryonic exposure to ketamine.
Felix, LM, Antunes, LM, Coimbra, AM, Valentim, AM (2017) Behavioral alterations of zebrafish larvae after early embryonic exposure to ketamine. Psychopharmacology 234 :549-558. ISSN: 0033-3158. doi: 10.1007/s00213-016-4491-7. (Impact factor, Quartile: 3.308, Q2).

Morphological and behavioral responses of zebrafish after 24h of ketamine embryonic exposure.
Felix, LM, Serafim, C, Martins, MJ, Valentim, AM, Antunes, LM, Matos, M, Coimbra, AM (2017) Morphological and behavioral responses of zebrafish after 24h of ketamine embryonic exposure. Toxicology And Applied Pharmacology 321 :27-36. ISSN: 0041-008X. doi: 10.1016/j.taap.2017.02.013. (Impact factor, Quartile: 3.791, Q1).

Projects

GREENValue - Valorisation of Resource Generation in Natural Space
Running

UTAD/CITAB Coordinator  /  José Laranjo
Start date  /  2022/07 Funding  /  COMPETE - REACT-EU Reference  /  POCI-07-62G4-FEDER-181589


Vine & Wine PT - Driving Sustainable Growth Through Smart Innovation
Running

Coordinator  /  Jorge Dias UTAD/CITAB Coordinator  /  Raul Santos
Start date  /  2021/11 Funding  /  IAPMEI - PRR - Recovery and Resilience Plan / Mobilising Agendas Reference  /  C644866286-00000011


INNOVINE&WINE – Vineyard and Wine Innovation Platform
Concluded

Coordinator  /  João Coutinho UTAD/CITAB Coordinator  /  João Santos
Start date  /  2016/04 Funding  /  Norte2020 Reference  /  NORTE-01-0145-FEDER-000038


Zebrafish (Danio rerio) anaesthesia and potential implications in research – reduction, replacement and refining
Concluded

Coordinator  /  Ana Maria Marques Valentim UTAD/CITAB Coordinator  /  Sandra Monteiro
Start date  /  2013/07 Funding  /  FCT Reference  /  PTDC/CVT-WEL/4672/2012


Biomonitorização em rios: uma aproximação integrada
Concluded

Coordinator  /  Rui Cortes
Start date  /  2011/01 Funding  /  FCT Reference  /  PTDC/BIA-ECS/114859/2009


Ovary apoptosis in zebrafish (Danio rerio): pathways characterization, role in sexual differentiation and as endocrine disruptors
Concluded

Coordinator  /  Ana Coimbra
Start date  /  2010/06 Funding  /  FCT Reference  /  PTDC/CVT/102453/2008


A modelação das vias de sinalização do ácido retinóico por contaminantes ambientais em teleósteos
Concluded

Coordinator  /  Miguel Alberto Fernandes Machado e Santos UTAD/CITAB Coordinator  /  Ana Coimbra
Start date  /  2008/09 Funding  /  FCT


An Integrative Study on the Toxipathic Lesions in Portuguese Estuarine Fishes – Assessing Injury Impact and Toxicogenomic Implications in Experimental Modes
Concluded

UTAD/CITAB Coordinator  /  António Fernandes
Funding  /  FCT (PTDC/MAR/70436/2006) Reference  /  FCT (PTDC/MAR/70436/2006)