Maria José Félix Saavedra Môcho Integrated Member

CV Ciência Vitae

BIO

Name: Maria José Félix Saavedra Môcho

Aggregation: Integrated Member

Scopus author ID: 8405237300

Orcid ID: 0000-0002-7492-4965

Ciência Vitae: 6A15-A626-87B0

Email: saavedra@utad.pt

Research Tasks

Integrated monitoring of climate and environmental impacts

Sustainability in agri-food and forestry ecosystems

Valorisation of bio-based products and and co-products

Publications

Assessing the ecological potential of reservoirs: a principal response curve (PRC) analysis approach

Cabecinha E., Pardal M., Cabral J.A., Monteiro S.M., Cortes R., Saavedra M.J., Varandas S., Van den Brink P., (2024) Assessing the ecological potential of reservoirs: a principal response curve (PRC) analysis approach Hydrobiologia 851 :25-44. ISSN: 15735117. doi: 10.1007/s10750-023-05310-7.

Environmental Health Assessment of the Northwest Portuguese Coast—Biochemical Biomarker Responses in the Marine Gastropod Phorcus lineatus

Santos D., Varandas S., Carrola J.S., Saavedra M.J., Luzio A., Monteiro S.M., Cabecinha E., (2024) Environmental Health Assessment of the Northwest Portuguese Coast—Biochemical Biomarker Responses in the Marine Gastropod Phorcus lineatus Water (Switzerland) 16 (5). ISSN: 20734441. doi: 10.3390/w16010005.

In Vitro Effect of Eucalyptus Essential Oils and Antiseptics (Chlorhexidine Gluconate and Povidone-Iodine) against Bacterial Isolates from Equine Wounds

Pimenta J., Dias C., Cotovio M., Saavedra M.J., (2024) In Vitro Effect of Eucalyptus Essential Oils and Antiseptics (Chlorhexidine Gluconate and Povidone-Iodine) against Bacterial Isolates from Equine Wounds Veterinary Sciences 11 (12). ISSN: 23067381. doi: 10.3390/vetsci11010012.

An Overview of Cefiderocol’s Therapeutic Potential and Underlying Resistance Mechanisms

Domingues S., Lima T., Saavedra M.J., Da Silva G.J., (2023) An Overview of Cefiderocol’s Therapeutic Potential and Underlying Resistance Mechanisms Life 13 (1427). ISSN: 20751729. doi: 10.3390/life13071427.

Antioxidant, Antibacterial, and Cosmeceutical Potential of Four Common Edible Mushrooms

Machado-Carvalho L., Martins T., Aires A., Saavedra M.J., Marques G., (2023) Antioxidant, Antibacterial, and Cosmeceutical Potential of Four Common Edible Mushrooms Applied Sciences (Switzerland) 13 (7357). ISSN: 20763417. doi: 10.3390/app13137357.

Drinking-water isolated Delftia acidovorans selectively coaggregates with partner bacteria and facilitates multispecies biofilm development

Afonso A.C., Gomes I.B., Saavedra M.J., C. Simões L., Simões M., (2023) Drinking-water isolated Delftia acidovorans selectively coaggregates with partner bacteria and facilitates multispecies biofilm development Science of the Total Environment 875 (162646). ISSN: 18791026. doi: 10.1016/j.scitotenv.2023.162646.

Escherichia coli Phylogenetic and Antimicrobial Pattern as an Indicator of Anthropogenic Impact on Threatened Freshwater Mussels

Varandas S., Fernandes C., Cabecinha E., Gomes S., da Silva G.J., Saavedra M.J., (2023) Escherichia coli Phylogenetic and Antimicrobial Pattern as an Indicator of Anthropogenic Impact on Threatened Freshwater Mussels Antibiotics 12 (1401). ISSN: 20796382. doi: 10.3390/antibiotics12091401.

Hydrocinnamic acid and perillyl alcohol are effective against Escherichia coli biofilms when used alone and combined with antibiotics

Sousa M., Afonso A.C., Saavedra M.J., Simões L.C., Simões M., (2023) Hydrocinnamic acid and perillyl alcohol are effective against Escherichia coli biofilms when used alone and combined with antibiotics Journal of Applied Microbiology 134 (lxad234). ISSN: 13652672. doi: 10.1093/jambio/lxad234.

Hydrocinnamic Acid and Perillyl Alcohol Potentiate the Action of Antibiotics against Escherichia coli

Sousa M., Afonso A.C., Teixeira L.S., Borges A., Saavedra M.J., Simões L.C., Simões M., (2023) Hydrocinnamic Acid and Perillyl Alcohol Potentiate the Action of Antibiotics against Escherichia coli Antibiotics 12 (360). ISSN: 20796382. doi: 10.3390/antibiotics12020360.

Nutraceutical Potential of Lentinula edodes’ Spent Mushroom Substrate: A Comprehensive Study on Phenolic Composition, Antioxidant Activity, and Antibacterial Effects

Baptista F., Campos J., Costa-Silva V., Pinto A.R., Saavedra M.J., Ferreira L.M., Rodrigues M., Barros A.N., (2023) Nutraceutical Potential of Lentinula edodes’ Spent Mushroom Substrate: A Comprehensive Study on Phenolic Composition, Antioxidant Activity, and Antibacterial Effects Journal of Fungi 9 (1200). ISSN: 2309608X. doi: 10.3390/jof9121200.

Sulfur-containing compounds from fungi

Garcia J., Silva J., Gouvinhas I., Guimarães R., Bovolini A., Saavedra M.J., Alves M.J., (2023) Sulfur-containing compounds from fungi Natural Secondary Metabolites: From Nature, Through Science, to Industry :647-672. doi: 10.1007/978-3-031-18587-8_20.

Unveiling the Potential of Unexplored Winery By-Products from the Dão Region: Phenolic Composition, Antioxidants, and Antimicrobial Properties

Costa C., Campos J., Gouvinhas I., Pinto A.R., Saavedra M.J., Novo Barros A., (2023) Unveiling the Potential of Unexplored Winery By-Products from the Dão Region: Phenolic Composition, Antioxidants, and Antimicrobial Properties Applied Sciences (Switzerland) 13 (10020). ISSN: 20763417. doi: 10.3390/app131810020.

Antimicrobial, Antibiofilm, and Antioxidant Properties of Boletus edulis and Neoboletus luridiformis Against Multidrug-Resistant ESKAPE Pathogens

Garcia J., Rodrigues F., Castro F., Aires A., Marques G., Saavedra M.J., (2022) Antimicrobial, Antibiofilm, and Antioxidant Properties of Boletus edulis and Neoboletus luridiformis Against Multidrug-Resistant ESKAPE Pathogens Frontiers in Nutrition 8 (773346). ISSN: 2296861X. doi: 10.3389/fnut.2021.773346.

Bioactive polysaccharides from medicinal mushrooms: A review on their isolation, structural characteristics and antitumor activity

Garcia J., Rodrigues F., Saavedra M.J., Nunes F.M., Marques G., (2022) Bioactive polysaccharides from medicinal mushrooms: A review on their isolation, structural characteristics and antitumor activity Food Bioscience 49 (101955). ISSN: 22124306. doi: 10.1016/j.fbio.2022.101955.

Exploring the Antibiotic Resistance Profile of Clinical Klebsiella pneumoniae Isolates in Portugal

Oliveira R., Castro J., Silva S., Oliveira H., Saavedra M.J., Azevedo N.F., Almeida C., (2022) Exploring the Antibiotic Resistance Profile of Clinical Klebsiella pneumoniae Isolates in Portugal Antibiotics 11 (1613). ISSN: 20796382. doi: 10.3390/antibiotics11111613.

Genomic epidemiological analysis of Klebsiella pneumoniae from Portuguese hospitals reveals insights into circulating antimicrobial resistance

Spadar A., Phelan J., Elias R., Modesto A., Caneiras C., Marques C., Lito L., Pinto M., Cavaco-Silva P., Ferreira H., Pomba C., Da Silva G.J., Saavedra M.J., Melo-Cristino J., Duarte A., Campino S., Perdigão J., Clark T.G., (2022) Genomic epidemiological analysis of Klebsiella pneumoniae from Portuguese hospitals reveals insights into circulating antimicrobial resistance Scientific Reports 12 (13791). ISSN: 20452322. doi: 10.1038/s41598-022-17996-1.

In vitro modulation of gilthead seabream (Sparus aurata L.) leukocytes by Bacillus spp. extracellular molecules upon bacterial challenge

Santos R.A., Mariz-Ponte N., Martins N., Magalhães R., Jerusik R., Saavedra M.J., Peres H., Oliva-Teles A., Serra C.R., (2022) In vitro modulation of gilthead seabream (Sparus aurata L.) leukocytes by Bacillus spp. extracellular molecules upon bacterial challenge Fish and Shellfish Immunology 121 :285-294. ISSN: 10959947. doi: 10.1016/j.fsi.2022.01.002.

Mesenchymal Stem Cell Studies in the Goat Model for Biomedical Research—A Review of the Scientific Literature

Dias I.E., Viegas C.A., Requicha J.F., Saavedra M.J., Azevedo J.M., Carvalho P.P., Dias I.R., (2022) Mesenchymal Stem Cell Studies in the Goat Model for Biomedical Research—A Review of the Scientific Literature Biology 11 (1276). ISSN: 20797737. doi: 10.3390/biology11091276.

Multiresistant bacteria: Invisible enemies of freshwater mussels

Saavedra M.J., Fernandes C., Teixeira A., Álvarez X., Varandas S., (2022) Multiresistant bacteria: Invisible enemies of freshwater mussels Environmental Pollution 295 (118671). ISSN: 18736424. doi: 10.1016/j.envpol.2021.118671.

Occurrence and seasonality of Campylobacter spp. in Portuguese dairy farms

Barata A.R., Nunes B., Oliveira R., Guedes H., Almeida C., Saavedra M.J., da Silva G.J., Almeida G., (2022) Occurrence and seasonality of Campylobacter spp. in Portuguese dairy farms International Journal of Food Microbiology 383 (109961). ISSN: 18793460. doi: 10.1016/j.ijfoodmicro.2022.109961.

Photodynamic therapy and combinatory treatments for the control of biofilm-associated infections

Ribeiro M., Gomes I.B., Saavedra M.J., Simões M., (2022) Photodynamic therapy and combinatory treatments for the control of biofilm-associated infections Letters in Applied Microbiology 75 :548-564. ISSN: 1472765X. doi: 10.1111/lam.13762.

Role of Goats in the Epidemiology of Coxiella burnetii

Anastácio S., de Sousa S.R., Saavedra M.J., da Silva G.J., (2022) Role of Goats in the Epidemiology of Coxiella burnetii Biology 11 (1703). ISSN: 20797737. doi: 10.3390/biology11121703.

Screening of Natural Molecules as Adjuvants to Topical Antibiotics to Treat Staphylococcus aureus from Diabetic Foot Ulcer Infections

Oliveira D., Borges A., Saavedra M.J., Borges F., Simões M., (2022) Screening of Natural Molecules as Adjuvants to Topical Antibiotics to Treat Staphylococcus aureus from Diabetic Foot Ulcer Infections Antibiotics 11 (620). ISSN: 20796382. doi: 10.3390/antibiotics11050620.

Bacillus spp. Inhibit edwardsiella tarda quorum-sensing and fish infection

Santos R.A., Monteiro M., Rangel F., Jerusik R., Saavedra M.J., Carvalho A.P., Oliva-Teles A., Serra C.R., (2021) Bacillus spp. Inhibit edwardsiella tarda quorum-sensing and fish infection Marine Drugs 19 (602). ISSN: 16603397. doi: 10.3390/md19110602.

Bacterial coaggregation in aquatic systems

Afonso A.C., Gomes I.B., Saavedra M.J., Giaouris E., Simões L.C., Simões M., (2021) Bacterial coaggregation in aquatic systems Water Research 196 (117037). ISSN: 18792448. doi: 10.1016/j.watres.2021.117037.

Biofilms in diabetic foot ulcers: Impact, risk factors and control strategies

Afonso A.C., Oliveira D., Saavedra M.J., Borges A., Simões M., (2021) Biofilms in diabetic foot ulcers: Impact, risk factors and control strategies International Journal of Molecular Sciences 22 (8278). ISSN: 14220067. doi: 10.3390/ijms22158278.

Black-and-white ruffed lemur (Varecia variegata) in captivity: Analysis of the oral microbiota in a one health perspective

Silva C., Requicha J.F., Martins J.J., Duarte A., Dias I.R., Viegas C.A., Saavedra M.J., (2021) Black-and-white ruffed lemur (Varecia variegata) in captivity: Analysis of the oral microbiota in a one health perspective Animals 11 (2905). ISSN: 20762615. doi: 10.3390/ani11102905.

Comparative antioxidant and antimicrobial properties of Lentinula edodes Donko and Koshin varieties against priority multidrug-resistant pathogens

Garcia J., Afonso A., Fernandes C., Nunes F.M., Marques G., Saavedra M.J., (2021) Comparative antioxidant and antimicrobial properties of Lentinula edodes Donko and Koshin varieties against priority multidrug-resistant pathogens South African Journal of Chemical Engineering 35 :98-106. ISSN: 10269185. doi: 10.1016/j.sajce.2020.09.008.

From soil to cosmetic industry: Validation of a new cosmetic ingredient extracted from chestnut shells

Pinto D., Cádiz-Gurrea M.d.l.L., Garcia J., Saavedra M.J., Freitas V., Costa P., Sarmento B., Delerue-Matos C., Rodrigues F., (2021) From soil to cosmetic industry: Validation of a new cosmetic ingredient extracted from chestnut shells Sustainable Materials and Technologies 29 (e00309). ISSN: 22149937. doi: 10.1016/j.susmat.2021.e00309.

Incorporation of untreated or white-rot fungi treated cowpea stover on performance, digestibility, health and meat quality of growing rabbits

Andrade E., Pinheiro V., Costa-Silva V., Marques G., Alves A., Serra C., Cone J.W., Saavedra M.J., Barros A., Ferreira L., Rodrigues M., (2021) Incorporation of untreated or white-rot fungi treated cowpea stover on performance, digestibility, health and meat quality of growing rabbits Animal Feed Science and Technology 281 (115100). doi: 10.1016/j.anifeedsci.2021.115100.

Isolation and Characterization of Fish-Gut Bacillus spp. as Source of Natural Antimicrobial Compounds to Fight Aquaculture Bacterial Diseases

Santos R.A., Oliva-Teles A., Pousão-Ferreira P., Jerusik R., Saavedra M.J., Enes P., Serra C.R., (2021) Isolation and Characterization of Fish-Gut Bacillus spp. as Source of Natural Antimicrobial Compounds to Fight Aquaculture Bacterial Diseases Marine Biotechnology 23 :276-293. ISSN: 14362236. doi: 10.1007/s10126-021-10022-x.

Multidrug-resistant serratia rubidaea strains in the oral microbiota of healthy horses

Pimenta J.d.C., Saavedra M.J., da Silva G.J., Cotovio M., (2021) Multidrug-resistant serratia rubidaea strains in the oral microbiota of healthy horses Open Veterinary Journal 11 :598-602. ISSN: 22186050. doi: 10.5455/OVJ.2021.v11.i4.9.

The role of aquatic ecosystems (River Tua, Portugal) as reservoirs of multidrug-resistant Aeromonas spp

Gomes S., Fernandes C., Monteiro S., Cabecinha E., Teixeira A., Varandas S., Saavedra M.J., (2021) The role of aquatic ecosystems (River Tua, Portugal) as reservoirs of multidrug-resistant Aeromonas spp Water (Switzerland) 13 (698). ISSN: 20734441. doi: 10.3390/w13050698.

Enhanced phytochemical composition and biological activities of grape (Vitis vinifera L.) Stems growing in low altitude regions

Gouvinhas I., Pinto R., Santos R., Saavedra M.J., Barros A.I., (2020) Enhanced phytochemical composition and biological activities of grape (Vitis vinifera L.) Stems growing in low altitude regions Scientia Horticulturae 265 (109248). doi: 10.1016/j.scienta.2020.109248.

Epidemiology of carbapenemase-producing Klebsiella pneumoniae in northern Portugal: Predominance of KPC-2 and OXA-48

Lopes E., Saavedra M.J., Costa E., de Lencastre H., Poirel L., Aires-de-Sousa M., (2020) Epidemiology of carbapenemase-producing Klebsiella pneumoniae in northern Portugal: Predominance of KPC-2 and OXA-48 Journal of Global Antimicrobial Resistance 22 :349-353. ISSN: 22137173. doi: 10.1016/j.jgar.2020.04.007.

Genomic epidemiology of carbapenemase producing klebsiella pneumoniae strains at a northern portuguese hospital enables the detection of a misidentified klebsiella variicola kpc-3 producing strain

Perdigão J., Caneiras C., Elias R., Modesto A., Spadar A., Phelan J., Campino S., Clark T.G., Costa E., Saavedra M.J., Duarte A., (2020) Genomic epidemiology of carbapenemase producing klebsiella pneumoniae strains at a northern portuguese hospital enables the detection of a misidentified klebsiella variicola kpc-3 producing strain Microorganisms 8 (1986) :1-18. ISSN: 20762607. doi: 10.3390/microorganisms8121986.

Phenolic profile and bioactive potential of stems and seed kernels of sweet cherry fruit

Afonso S., Oliveira I.V., Meyer A.S., Aires A., Saavedra M.J., Gonçalves B., (2020) Phenolic profile and bioactive potential of stems and seed kernels of sweet cherry fruit Antioxidants 9 (1295) :1-17. ISSN: 20763921. doi: 10.3390/antiox9121295.

Potential application of grape (Vitis vinifera L.) stem extracts in the cosmetic and pharmaceutical industries: Valorization of a by-product

Leal C., Gouvinhas I., Santos R.A., Rosa E., Silva A.M., Saavedra M.J., Barros A.I.R.N.A., (2020) Potential application of grape (Vitis vinifera L.) stem extracts in the cosmetic and pharmaceutical industries: Valorization of a by-product Industrial Crops and Products 154 (112675). doi: 10.1016/j.indcrop.2020.112675.

Prevalence and serotypes of Shiga toxinproducing Escherichia coli (STEC) in dairy cattle from Northern Portugal.

Ballem, A.; Gonçalves, S.; Garcia-Meniño, I.; Flament-Simon, SC.; Blanco, JE; Fernandes, C.; Saavedra, MJ.; Pinto, C.; Oliveira, H.; Blanco, J.; Almeida, G.; Almeida, C. (2020) Prevalence and serotypes of Shiga toxinproducing Escherichia coli (STEC) in dairy cattle from Northern Portugal. PLOS ONE 15 (12) :e0244713. doi: 10.1371/journal.pone.0244713. (Impact factor, Quartile: 2.740, Q2).

Recovery of bioactive compounds from white grape (Vitis vinifera L.) stems as potential antimicrobial agents for human health

Leal C., Santos R.A., Pinto R., Queiroz M., Rodrigues M., José Saavedra M., Barros A., Gouvinhas I., (2020) Recovery of bioactive compounds from white grape (Vitis vinifera L.) stems as potential antimicrobial agents for human health Saudi Journal of Biological Sciences 27 :1009-1015. doi: 10.1016/j.sjbs.2020.02.013.

Irrigation deficit turns almond by-products into a valuable source of antimicrobial (poly)phenols

Prgomet I., Gonçalves B., Domínguez-Perles R., Santos R., Saavedra M.J., Aires A., Pascual-Seva N., Barros A., (2019) Irrigation deficit turns almond by-products into a valuable source of antimicrobial (poly)phenols Industrial Crops and Products 132 :186-196. doi: 10.1016/j.indcrop.2019.02.024.

Virulence, attachment and invasion of Caco-2 cells by multidrug-resistant bacteria isolated from wild animals

Dias C., Ribeiro M., Correia-Branco A., Domínguez-Perles R., Martel F., Saavedra M.J., Simões M., (2019) Virulence, attachment and invasion of Caco-2 cells by multidrug-resistant bacteria isolated from wild animals Microbial Pathogenesis 128 :230-235. ISSN: 10961208. doi: 10.1016/j.micpath.2019.01.011.

Biofilm formation and multidrug-resistant Aeromonas spp. from wild animals.

Dias, Carla; Borges, Anabela; Saavedra, Maria Jose; Simoes, Manuel (2018) Biofilm formation and multidrug-resistant Aeromonas spp. from wild animals. Journal Of Global Antimicrobial Resistance 12 :227-234. doi: 10.1016/j.jgar.2017.09.010. (Impact factor, Quartile: 2.022, Q3).

Biofilms and antibiotic susceptibility of multidrug-resistant bacteria from wild animals.

Dias, Carla; Borges, Anabela; Oliveira, Diana; Martinez-Murcia, Antonio; Saavedra, Maria Jose; Simoes, Manuel (2018) Biofilms and antibiotic susceptibility of multidrug-resistant bacteria from wild animals. Peerj 6. doi: 10.7717/peerj.4974. (Impact factor, Quartile: 2.118, Q2).

Monitoring the antioxidant and antimicrobial power of grape (Vitis vinifera L.) stems phenolics over long-term storage.

Gouvinhas, Irene; Santos, Rafaela A.; Queiroz, M.; Leal, Carla; Saavedra, Maria José; Domínguez-Perles, Raul; Rodrigues, Miguel; Barros, Ana I.R.N.A. (2018) Monitoring the antioxidant and antimicrobial power of grape (Vitis vinifera L.) stems phenolics over long-term storage. INDUSTRIAL CROPS AND PRODUCTS 126 :83-91. doi: 10.1016/j.indcrop.2018.10.006. (Impact factor, Quartile: 3.849, Q1).

Analysis of glycosylated flavonoids extracted from sweet-cherry stems, as antibacterial agents against pathogenic Escherichia coli isolates.

Aires, A, Dias, C, Carvalho, R, Saavedra, MJ (2017) Analysis of glycosylated flavonoids extracted from sweet-cherry stems, as antibacterial agents against pathogenic Escherichia coli isolates. Acta Biochimica Polonica 64 :265-271. ISSN: 0001-527X. doi: 10.18388/abp.2016_1374. (Impact factor, Quartile: 1.105, Q4).

Reuse potential of vegetable wastes (broccoli, green bean and tomato) for the recovery of antioxidant phenolic acids and flavonoids.

Aires, A, Carvalho, R, Saavedra, MJ (2017) Reuse potential of vegetable wastes (broccoli, green bean and tomato) for the recovery of antioxidant phenolic acids and flavonoids. International Journal Of Food Science And Technology 52 :98-107. ISSN: 0950-5423. doi: 10.1111/ijfs.13256. (Impact factor, Quartile: 1.64, Q2).

Projects