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Paula Alexandra Martins de Oliveira Integrated Member

BIO

Name: Paula Alexandra Martins de Oliveira

Aggregation: Integrated Member

Scopus author ID: 11939992300

Orcid ID: 0000-0001-9519-4044

Ciência Vitae: FA10-57EE-CA2B

Email: pamo@utad.pt

Research Tasks

Valorisation of bio-based products and and co-products

Publications

Aloysia citrodora extract as a chemopreventive agent against HPV16-induced lesions: findings from K14-HPV16 mice
Medeiros-Fonseca B., Faustino-Rocha A.I., Silva J., Silva M.G., Pires M.J., Neuparth M.J., Vala H., Vasconcelos-Nóbrega C., Dias M.I., Barros L., Gonçalves L., Gaivão I., Bastos M.M.S.M., Félix L., Venâncio C., Medeiros R., Gil da Costa R.M., Oliveira P.A., (2024) Aloysia citrodora extract as a chemopreventive agent against HPV16-induced lesions: findings from K14-HPV16 mice Exploration of Medicine 5 :416-433. ISSN: 26923106. doi: 10.37349/emed.2024.00228.
AT11-guided liposomes for oral cancer cells: From characterization towards in vitro evaluation
Lopes-Nunes J., Cabral Campello M.P., Paulo A., Nastruzzi C., Oliveira P.A., Cruz C., (2024) AT11-guided liposomes for oral cancer cells: From characterization towards in vitro evaluation Journal of Drug Delivery Science and Technology 101 (106214). doi: 10.1016/j.jddst.2024.106214.
Development Features on the Selection of Animal Models for Teratogenic Testing
Alves-Pimenta S., Colaço B., Oliveira P.A., Venâncio C., (2024) Development Features on the Selection of Animal Models for Teratogenic Testing Methods in Molecular Biology 2753 :67-104. ISSN: 19406029. doi: 10.1007/978-1-0716-3625-1_3.
Do endocrine disrupting compounds impact earthworms? A comprehensive evidence review
Azevedo T., Gonçalves M., Silva-Reis R., Medeiros-Fonseca B., Roboredo M., Sousa J.R., Oliveira P.A., Pinto M.d.L., Peixoto F., Gaivão I., Matos M., Coimbra A.M., (2024) Do endocrine disrupting compounds impact earthworms? A comprehensive evidence review Reviews in Environmental Science and Biotechnology 23 :633-677. ISSN: 15729826. doi: 10.1007/s11157-024-09698-z.
Effect of lemon juice enriched with melatonin (Citrus lemon L.) in the treatment of K14HPV16 mice
El Hilali F.B., Medeiros-Fonseca B., Oliveira P.A., Valero D., (2024) Effect of lemon juice enriched with melatonin (Citrus lemon L.) in the treatment of K14HPV16 mice Acta Horticulturae :25-30. ISSN: 24066168. doi: 10.17660/ACTAHORTIC.2024.1387.3.
G-quadruplex forming motifs in the promoter region of the B-MYB proto-oncogene
Miranda A., Cucchiarini A., Esnault C., Andrau J.C., Oliveira P.A., Mergny J.L., Cruz C., (2024) G-quadruplex forming motifs in the promoter region of the B-MYB proto-oncogene International Journal of Biological Macromolecules 270 (132244). ISSN: 18790003. doi: 10.1016/j.ijbiomac.2024.132244.
Guidelines on Developmental Toxicity Tests: Brief Insights
Alves-Pimenta S., Félix L., Colaço B., Oliveira P.A., Venâncio C., (2024) Guidelines on Developmental Toxicity Tests: Brief Insights Methods in Molecular Biology 2753 :39-65. ISSN: 19406029. doi: 10.1007/978-1-0716-3625-1_2.
Heavy metal and metalloid concentrations in red deer (Cervus elaphus) and their human health implications from One Health perspective
Jota Baptista C., Seixas F., Gonzalo-Orden J.M., Patinha C., Pato P., Ferreira da Silva E., Fernandes G., Oliveira P.A., (2024) Heavy metal and metalloid concentrations in red deer (Cervus elaphus) and their human health implications from One Health perspective Environmental Geochemistry and Health 46 (226). ISSN: 15732983. doi: 10.1007/s10653-024-01991-8.
Heavy metals and metalloids in wild boars (Sus Scrofa) – a silent but serious public health hazard
Jota Baptista C., Seixas F., Gonzalo-Orden J.M., Patinha C., Pato P., Ferreira da Silva E., Merino-Goyenechea L.J., Oliveira P.A., (2024) Heavy metals and metalloids in wild boars (Sus Scrofa) – a silent but serious public health hazard Veterinary Research Communications 48 :1015-1023. ISSN: 15737446. doi: 10.1007/s11259-023-10272-1.
Histopathology lesions in red deer (Cervus elaphus) from Idanha-a-Nova and Lousã (Portugal): preliminary results
Jota Baptista C., Oliveira P.A., Gonzalo-Orden J.M., Fernandes G., Seixas F., (2024) Histopathology lesions in red deer (Cervus elaphus) from Idanha-a-Nova and Lousã (Portugal): preliminary results Veterinarska Stanica 55 :137-145. ISSN: 18491170. doi: 10.46419/vs.55.2.2.
How to Design a Biomonitoring Study – A Practical Guide for Veterinary Professionals under a One Health Approach
Baptista C.J., Seixas F., Gonzalo-Orden J.M., Oliveira P.A., (2024) How to Design a Biomonitoring Study – A Practical Guide for Veterinary Professionals under a One Health Approach World's Veterinary Journal 14 :461-546. ISSN: 23224568. doi: 10.54203/scil.2024.wvj53.
Impact of ozone therapy on mouse liver mitochondrial function and antioxidant system
Oliveira M.M., Correia S., Peirone C., Magalhães M., Oliveira P., Peixoto F., (2024) Impact of ozone therapy on mouse liver mitochondrial function and antioxidant system Biochimie 223 :116-124. ISSN: 61831638. doi: 10.1016/j.biochi.2024.03.014.
Interplay Between Western Diet and Mammary Cancer: Data from a Chemically-induced Model in Wistar Rats
Silva J., Azevedo T., Aires I., Peixoto F., Neuparth M.J., Queiroga F.L., Seixas F., Ferreira R., Faustino-Rocha A.I., Duarte J.A., Oliveira P.A., (2024) Interplay Between Western Diet and Mammary Cancer: Data from a Chemically-induced Model in Wistar Rats Anticancer Research 44 :4843-4856. ISSN: 17917530. doi: 10.21873/anticanres.17310.
Lifelong exercise training promotes the remodelling of the immune system and prostate signalome in a rat model of prostate carcinogenesis
Nascimento-Gonçalves E., Seixas F., Palmeira C., Martins G., Fonseca C., Duarte J.A., Faustino-Rocha A.I., Colaço B., Pires M.J., Neuparth M.J., Moreira-Gonçalves D., Fardilha M., Henriques M.C., Patrício D., Pelech S., Ferreira R., Oliveira P.A., (2024) Lifelong exercise training promotes the remodelling of the immune system and prostate signalome in a rat model of prostate carcinogenesis GeroScience 46 :817-840. ISSN: 25092723. doi: 10.1007/s11357-023-00806-5.
Long-term effects of the chronic administration of doxorubicin on aged skeletal muscle: An exploratory study in mice
Moreira-Pais A., Ferreira R., Baltazar T., Neuparth M.J., Vitorino R., Reis-Mendes A., Costa V.M., Oliveira P.A., Duarte J.A., (2024) Long-term effects of the chronic administration of doxorubicin on aged skeletal muscle: An exploratory study in mice Biochemical and Biophysical Research Communications 733 (150650). ISSN: 10902104. doi: 10.1016/j.bbrc.2024.150650.
Mitochondrial remodeling underlying age-induced skeletal muscle wasting: let's talk about sex
Moreira-Pais A., Vitorino R., Sousa-Mendes C., Neuparth M.J., Nuccio A., Luparello C., Attanzio A., Novák P., Loginov D., Nogueira-Ferreira R., Leite-Moreira A., Oliveira P.A., Ferreira R., Duarte J.A., (2024) Mitochondrial remodeling underlying age-induced skeletal muscle wasting: let's talk about sex Free Radical Biology and Medicine 218 :68-81. ISSN: 18734596. doi: 10.1016/j.freeradbiomed.2024.04.005.
Natural products-based antiangiogenic agents: New frontiers in cancer therapy
Azevedo T., Ferreira T., Peña-Corona S.I., Cortes H., Silva-Reis R., da Costa R.M.G., Faustino-Rocha A.I., Oliveira P.A., Calina D., Cardoso S.M., Büsselberg D., Leyva-Gómez G., Sharifi-Rad J., Cho W.C., (2024) Natural products-based antiangiogenic agents: New frontiers in cancer therapy Food Frontiers ISSN: 26438429. doi: 10.1002/fft2.466.
Relation between Infrared Thermometry and Thermal Imaging for Assessment of Rodents’ Body Temperature: A Way to Improve Animal Welfare
Oliveira P.A., Gonçalves L., Gonçalves M., Venâncio C., Azevedo T., Ribeiro C., Reis R., Faustino-Rocha A.I., (2024) Relation between Infrared Thermometry and Thermal Imaging for Assessment of Rodents’ Body Temperature: A Way to Improve Animal Welfare International Journal of Veterinary Science 13 :391-400. ISSN: 23054360. doi: 10.47278/journal.ijvs/2024.133.
The Effect of Lemon Juice (Citrus limon L.) Treated with Melatonin on the Health Status and Treatment of K14HPV16 Mice
Badiche-El Hilali F., Medeiros-Fonseca B., Silva J., Silvestre-Ferreira A.C., Pires M.J., Gil da Costa R.M., Peixoto F., Oliveira P.A., Valero D., (2024) The Effect of Lemon Juice (Citrus limon L.) Treated with Melatonin on the Health Status and Treatment of K14HPV16 Mice Antioxidants 13 (588). ISSN: 20763921. doi: 10.3390/antiox13050588.
The first full study of heavy metal(loid)s in western-European hedgehogs (Erinaceus europaeus) from Portugal
Jota Baptista C., Seixas F., Gonzalo-Orden J.M., Patinha C., Pato P., Ferreira da Silva E., Casero M., Brazio E., Brandão R., Costa D., Mateus T.L., Coelho A.C., Oliveira P.A., (2024) The first full study of heavy metal(loid)s in western-European hedgehogs (Erinaceus europaeus) from Portugal Environmental Science and Pollution Research 31 :11983-11994. ISSN: 16147499. doi: 10.1007/s11356-024-31877-2.
The veterinary medicinal products market supply gap: A practical insight based on the Regulation (EU) 2019/6
Nogueira R., Baptista C.J., Gonçalves L., Coelho A.C., Faustino-Rocha A.I., Purriños M.R., Gonzalo-Orden J.M., Oliveira P.A., (2024) The veterinary medicinal products market supply gap: A practical insight based on the Regulation (EU) 2019/6 Revista de Ciencias Agroveterinarias 23 :153-158. ISSN: 22381171. doi: 10.5965/223811712312024153.
Unlocking the therapeutic treasure of pomegranate leaf: A comprehensive review on phytochemical compounds, health benefits, and future prospects
Yu M., Gouvinhas I., Chen J., Zhu Y., Deng J., Xiang Z., Oliveira P., Xia C., Barros A., (2024) Unlocking the therapeutic treasure of pomegranate leaf: A comprehensive review on phytochemical compounds, health benefits, and future prospects Food Chemistry: X 23 (101587). ISSN: 25901575. doi: 10.1016/j.fochx.2024.101587.
Urinary tract bacterial infections in small animal practice: clinical and epidemiological aspects
Pereira A., Jota Baptista C., Oliveira P.A., Coelho A.C., (2024) Urinary tract bacterial infections in small animal practice: clinical and epidemiological aspects Veterinarska Stanica 55 :703-720. ISSN: 18491170. doi: 10.46419/vs.55.6.8.
Vermicomposting as a Valorization Solution to the Winery Sector By-Products
Nascimento-Gonçalves E., Azevedo T., Lopes H., Sousa J.R., Oliveira P.A., Roboredo M., Coimbra A.M., Morais M.C., (2024) Vermicomposting as a Valorization Solution to the Winery Sector By-Products Agronomy 14 (1111). ISSN: 20734395. doi: 10.3390/agronomy14061111.
Animal Models in Phytopharmacology and Toxicological Testing of Plant Products
Faustino-Rocha A.I., Medeiros-Fonseca B., Vala H., Pires M.J., Vasconcelos-Nóbrega C., Oliveira P.A., (2023) Animal Models in Phytopharmacology and Toxicological Testing of Plant Products Ethnobotany and Ethnopharmacology of Medicinal and Aromatic Plants: Steps Towards Drug Discovery :289-306. doi: 10.1201/b22842-16.
Anti-Inflammatory, Anti-Oxidative and Anti-Apoptotic Effects of Thymol and 24-Epibrassinolide in Zebrafish Larvae
Lanzarin G.A.B., Félix L.M., Monteiro S.M., Ferreira J.M., Oliveira P.A., Venâncio C., (2023) Anti-Inflammatory, Anti-Oxidative and Anti-Apoptotic Effects of Thymol and 24-Epibrassinolide in Zebrafish Larvae Antioxidants 12 (1297). ISSN: 20763921. doi: 10.3390/antiox12061297.
Antitumor Effects of Cannabis sativa Bioactive Compounds on Colorectal Carcinogenesis
Silva-Reis R., Silva A.M.S., Oliveira P.A., Cardoso S.M., (2023) Antitumor Effects of Cannabis sativa Bioactive Compounds on Colorectal Carcinogenesis Biomolecules 13 (764). ISSN: 2218273X. doi: 10.3390/biom13050764.
Appraising Animal Models of Prostate Cancer for Translational Research: Future Directions
Nascimento-Goncalves E., Seixas F., Gil Da Costa R.M., Pires M.J., Neuparth M.J., Moreira-Goncalves D., Fardilha M., Faustino-Rocha A.I., Colaco B., Ferreira R., Oliveira P.A., (2023) Appraising Animal Models of Prostate Cancer for Translational Research: Future Directions Anticancer Research 43 :275-281. ISSN: 17917530. doi: 10.21873/anticanres.16160.
Biomonitoring of heavy metals and metalloids with wild mammals in the Iberian Peninsula: a systematic review
Baptista C.J., Seixas F., Gonzalo-Orden J.M., Oliveira P.A., (2023) Biomonitoring of heavy metals and metalloids with wild mammals in the Iberian Peninsula: a systematic review Environmental Reviews 31 :66-75. doi: 10.1139/er-2022-0071.
Carcinogenesis
Jota Baptista C.V., Faustino-Rocha A.I., Seixas F., Oliveira P.A., (2023) Carcinogenesis Encyclopedia of Toxicology, Fourth Edition: Volume 1-9 2 :V2-597-V2-618. doi: 10.1016/B978-0-12-824315-2.00124-X.
Cytinus hypocistis (L.) L. extract effects in an animal model of papillomavirus-induced neoplasia
Medeiros C., Silva A.R., Ferreira T., Barros L., Neuparth M.J., Peixoto F., Bastos M.M.S.M., Medeiros R., Gil da Costa R.M., Pires M.J., Faustino-Rocha A.I., Gama A., Oliveira P.A., (2023) Cytinus hypocistis (L.) L. extract effects in an animal model of papillomavirus-induced neoplasia Veterinarska Stanica 54 :637-653. ISSN: 18491170. doi: 10.46419/vs.54.6.9.
Do Urban Hedgehogs (Erinaceus europaeus) Represent a Relevant Source of Zoonotic Diseases?
Jota Baptista C., Oliveira P.A., Gonzalo-Orden J.M., Seixas F., (2023) Do Urban Hedgehogs (Erinaceus europaeus) Represent a Relevant Source of Zoonotic Diseases? Pathogens 12 (268). ISSN: 20760817. doi: 10.3390/pathogens12020268.
Evolution of Models of Prostate Cancer: Their Contribution to Current Therapies
Faustino-Rocha A.I., Jota-Baptista C., Nascimento-Gonçalves E., Oliveira P.A., (2023) Evolution of Models of Prostate Cancer: Their Contribution to Current Therapies Anticancer Research 43 :323-333. ISSN: 17917530. doi: 10.21873/anticanres.16167.
First morphological and molecular isolation of Talaromyces marneffei in beech marten (Martes foina) in Portugal
Matos A.C., Jota Baptista C., Oliveira P.A., Soares A.S., Figueira L., Matos M., Coelho A.C., (2023) First morphological and molecular isolation of Talaromyces marneffei in beech marten (Martes foina) in Portugal Research in Veterinary Science 162 (104945). ISSN: 15322661. doi: 10.1016/j.rvsc.2023.104945.
First report of intestinal intussusception in Western European hedgehogs (Erinaceus europaeus)
Jota Baptista C., Gonzalo-Orden J.M., Casero M., Oliveira P.A., Seixas F., (2023) First report of intestinal intussusception in Western European hedgehogs (Erinaceus europaeus) Veterinary Record Case Reports 11 (e720). ISSN: 20526121. doi: 10.1002/vrc2.720.
Glycolysis and skeletal muscle plasticity: lactate as a key signaling molecule
Moreira-Pais A., Ferreira R., Oliveira P.A., Neuparth M.J., Appell H.J., Duarte J.A., (2023) Glycolysis and skeletal muscle plasticity: lactate as a key signaling molecule Glycolysis: Tissue-Specific Metabolic Regulation in Physio-pathological Conditions :51-74. doi: 10.1016/B978-0-323-91704-9.00013-6.
Hedgehogs and Biomonitoring Heavy Metal(loid)s
Baptista C.J., Seixas F., Gonzalo-Orden J.M., Oliveira P.A., (2023) Hedgehogs and Biomonitoring Heavy Metal(loid)s Journal of Advanced Veterinary Research 13 :1706-1708. ISSN: 20906277.
High Levels of Heavy Metal(loid)s Related to Biliary Hyperplasia in Hedgehogs (Erinaceus europaeus)
Jota Baptista C., Seixas F., Gonzalo-Orden J.M., Patinha C., Pato P., Ferreira da Silva E., Casero M., Brazio E., Brandão R., Costa D., Mateus T.L., Oliveira P.A., (2023) High Levels of Heavy Metal(loid)s Related to Biliary Hyperplasia in Hedgehogs (Erinaceus europaeus) Animals 13 (1359). ISSN: 20762615. doi: 10.3390/ani13081359.
In vivo prostate cancer research: Key interspecies prostate anatomical features for translation medicine
Nascimento-Gonçalves E., Seixas F., Ferreira R., Oliveira P.A., Colaço B., (2023) In vivo prostate cancer research: Key interspecies prostate anatomical features for translation medicine Open Veterinary Journal 13 :782-793. ISSN: 22186050. doi: 10.5455/OVJ.2023.v13.i6.13.
Klotho in Cancer: Potential Diagnostic and Prognostic Applications
Mota J., Lima A.M.M., Gomes J.I.S., Souza de Andrade M., Brito H.O., Silva M.M.A.L., Faustino-Rocha A.I., Oliveira P.A., Lopes F.F., Gil da Costa R.M., (2023) Klotho in Cancer: Potential Diagnostic and Prognostic Applications Diagnostics 13 (3357). ISSN: 20754418. doi: 10.3390/diagnostics13213357.
Mammary Glands of Women, Female Dogs and Female Rats: Similarities and Differences to Be Considered in Breast Cancer Research
Ferreira T., Gama A., Seixas F., Faustino-Rocha A.I., Lopes C., Gaspar V.M., Mano J.F., Medeiros R., Oliveira P.A., (2023) Mammary Glands of Women, Female Dogs and Female Rats: Similarities and Differences to Be Considered in Breast Cancer Research Veterinary Sciences 10 (379). ISSN: 23067381. doi: 10.3390/vetsci10060379.
Quercus spp. extract as a promising preventive or therapeutic strategy for cancer: A systematic review
Oliveira P.A., Medeiros-Fonseca B., Vasconcelos-Nóbrega C., Alvarado A., Pires M.J., Vala H., Barros A.I.R.N.A., Faustino-Rocha A.I., (2023) Quercus spp. extract as a promising preventive or therapeutic strategy for cancer: A systematic review Molecular Medicine Reports 28 (175). ISSN: 17913004. doi: 10.3892/mmr.2023.13062.
Realistic aspects behind the application of the rat model of chemically-induced mammary cancer: Practical guidelines to obtain the best results
Silva J., Faustino-Rocha A.I., Duarte J.A., Oliveira P.A., (2023) Realistic aspects behind the application of the rat model of chemically-induced mammary cancer: Practical guidelines to obtain the best results Veterinary World 16 :1222-1230. ISSN: 22310916. doi: 10.14202/vetworld.2023.1222-1230.
Study on the antineoplastic and toxicological effects of pomegranate (Punica granatum L.) leaf infusion using the K14-HPV16 transgenic mouse model
Yu M., Gouvinhas I., Pires M.J., Neuparth M.J., Costa R.M.G.d., Medeiros R., Bastos M.M.S.M., Vala H., Félix L., Venâncio C., Barros A.I.R.N.A., Oliveira P.A., (2023) Study on the antineoplastic and toxicological effects of pomegranate (Punica granatum L.) leaf infusion using the K14-HPV16 transgenic mouse model Food and Chemical Toxicology 174 (113689). ISSN: 18736351. doi: 10.1016/j.fct.2023.113689.
Studying and Analyzing Humane Endpoints in the Fructose-Fed and Streptozotocin-Injected Rat Model of Diabetes
Silva-Reis R., Faustino-Rocha A.I., Silva J., Valada A., Azevedo T., Anjos L., Gonçalves L., Pinto M.d.L., Ferreira R., Silva A.M.S., Cardoso S.M., Oliveira P.A., (2023) Studying and Analyzing Humane Endpoints in the Fructose-Fed and Streptozotocin-Injected Rat Model of Diabetes Animals 13 (1397). ISSN: 20762615. doi: 10.3390/ani13081397.
The Impact of Resveratrol-Enriched Bread on Cardiac Remodeling in a Preclinical Model of Diabetes
Silva A.F.R., Silva-Reis R., Ferreira R., Oliveira P.A., Faustino-Rocha A.I., Pinto M.d.L., Coimbra M.A., Silva A.M.S., Cardoso S.M., (2023) The Impact of Resveratrol-Enriched Bread on Cardiac Remodeling in a Preclinical Model of Diabetes Antioxidants 12 (1066). ISSN: 20763921. doi: 10.3390/antiox12051066.
Wild boar (Sus scrofa) as a potential reservoir of infectious agents in Portugal: a review of two decades (2001–2021)
Jota Baptista C., Seixas F., Gonzalo-Orden J.M., Oliveira P.A., (2023) Wild boar (Sus scrofa) as a potential reservoir of infectious agents in Portugal: a review of two decades (2001–2021) European Journal of Wildlife Research 69 (101). ISSN: 14390574. doi: 10.1007/s10344-023-01732-9.
A quick and low-intensity method for oral administration to large numbers of mice: A possible alternative to oral gavage
Neto T., Faustino-Rocha A.I., Gil da Costa R.M., Medeiros R., Oliveira P.A., (2022) A quick and low-intensity method for oral administration to large numbers of mice: A possible alternative to oral gavage Laboratory Animals 56 :185-190. ISSN: 17581117. doi: 10.1177/00236772211035250.
An Integrative Approach to Characterize the Early Phases of Dimethylhydrazine‐Induced Colorectal Carcinogenesis in the Rat
Silva‐reis R., Castro-Ribeiro C., Gonçalves M., Ferreira T., Pires M.J., Iglesias‐aguirre C.E., Cortés‐martín A., Selma M.V., Espín J.C., Nascimento‐gonçalves E., Moreira‐pais A., Neuparth M.J., Peixoto F., Rosa E., Gama A., Ferreira R., Oliveira P.A., Faustino‐rocha A.I., (2022) An Integrative Approach to Characterize the Early Phases of Dimethylhydrazine‐Induced Colorectal Carcinogenesis in the Rat Biomedicines 10 (409). ISSN: 22279059. doi: 10.3390/biomedicines10020409.
Beneficial Effects of Broccoli (Brassica oleracea var italica) By-products in Diet-induced Obese Mice
Martins T., Leite R., Matos A.F., Soares J., Pires M.J., de Lurdes Pinto M., Neuparth M.J., Sequeira A.R., Félix L., Venâncio C., Monteiro S.M., Colaço B., Gouvinhas I., Barros A.I., Rosa E., Oliveira P.A., Antunes L.M., (2022) Beneficial Effects of Broccoli (Brassica oleracea var italica) By-products in Diet-induced Obese Mice In Vivo 36 :2173-2185. ISSN: 17917549. doi: 10.21873/invivo.12943.
Biomonitoring metals and metalloids in wild mammals: invasive versus non-invasive sampling
Jota Baptista C., Seixas F., Gonzalo-Orden J.M., Oliveira P.A., (2022) Biomonitoring metals and metalloids in wild mammals: invasive versus non-invasive sampling Environmental Science and Pollution Research 29 :18398-18407. ISSN: 16147499. doi: 10.1007/s11356-022-18658-5.
Characterization of the Human Papillomavirus 16 Oncogenes in K14HPV16 Mice: Sublineage A1 Drives Multi-Organ Carcinogenesis
Cochicho D., Nunes A., Gomes J.P., Martins L., Cunha M., Medeiros-Fonseca B., Oliveira P., Bastos M.M.S.M., Medeiros R., Mendonça J., Vieira L., Gil da Costa R.M., Felix A., (2022) Characterization of the Human Papillomavirus 16 Oncogenes in K14HPV16 Mice: Sublineage A1 Drives Multi-Organ Carcinogenesis International Journal of Molecular Sciences 23 (12371). ISSN: 14220067. doi: 10.3390/ijms232012371.
Characterizing the Inflammatory Microenvironment in K14-HPV16 Transgenic Mice: Mast Cell Infiltration and MicroRNA Expression
Costa A.C., Santos J.M.O., Medeiros-Fonseca B., Oliveira P.A., Bastos M.M.S.M., Brito H.O., da Costa R.M.G., Medeiros R., (2022) Characterizing the Inflammatory Microenvironment in K14-HPV16 Transgenic Mice: Mast Cell Infiltration and MicroRNA Expression Cancers 14 (2216). ISSN: 20726694. doi: 10.3390/cancers14092216.
Comparison of Gelatin Flavors for Oral Dosing of C57BL/6J and FVB/N Mice
Martins T., Matos A.F., Soares J., Leite R., Pires M.J., Ferreira T., Medeiros-Fonseca B., Rosa E., Oliveira P.A., Antunes L.M., (2022) Comparison of Gelatin Flavors for Oral Dosing of C57BL/6J and FVB/N Mice Journal of the American Association for Laboratory Animal Science 61 :89-95. doi: 10.30802/AALAS-JAALAS-21-000045.
Decoding the role of inflammation-related microRNAs in cancer cachexia: a study using HPV16-transgenic mice and in silico approaches
Santos J.M.O., Peixoto da Silva S., Bastos M.M.S.M., Oliveira P.A., Gil da Costa R.M., Medeiros R., (2022) Decoding the role of inflammation-related microRNAs in cancer cachexia: a study using HPV16-transgenic mice and in silico approaches Journal of Physiology and Biochemistry 78 :439-455. ISSN: 18778755. doi: 10.1007/s13105-021-00866-1.
Dicoumarol: from chemistry to antitumor benefits
Silva V.L.M., Silva-Reis R., Moreira-Pais A., Ferreira T., Oliveira P.A., Ferreira R., Cardoso S.M., Sharifi-Rad J., Butnariu M., Costea M.A., Grozea I., (2022) Dicoumarol: from chemistry to antitumor benefits Chinese Medicine (United Kingdom) 17 (145). ISSN: 17498546. doi: 10.1186/s13020-022-00699-0.
Effect of a Sub-Chronic Oral Exposure of Broccoli (Brassica oleracea L. Var. Italica) By-Products Flour on the Physiological Parameters of FVB/N Mice: A Pilot Study
Martins T., Oliveira P.A., Pires M.J., Neuparth M.J., Lanzarin G., Félix L., Venâncio C., Pinto M.d.L., Ferreira J., Gaivão I., Barros A.I., Rosa E., Antunes L.M., (2022) Effect of a Sub-Chronic Oral Exposure of Broccoli (Brassica oleracea L. Var. Italica) By-Products Flour on the Physiological Parameters of FVB/N Mice: A Pilot Study Foods 11 (120). ISSN: 23048158. doi: 10.3390/foods11010120.
Effects of Age and Lifelong Moderate-Intensity Exercise Training on Rats’ Testicular Function
Silva J.V., Santiago J., Matos B., Henriques M.C., Patrício D., Martins A.D., Duarte J.A., Ferreira R., Alves M.G., Oliveira P., Oliveira P.F., Fardilha M., (2022) Effects of Age and Lifelong Moderate-Intensity Exercise Training on Rats’ Testicular Function International Journal of Molecular Sciences 23 (11619). ISSN: 14220067. doi: 10.3390/ijms231911619.
Effects of testosterone and exercise training on bone microstructure of rats
Jota-Baptista C., Faustino-Rocha A.I., Fardilha M., Ferreira R., Oliveira P.A., Regueiro-Purriños M., Rodriguez-Altonaga J.A., Gonzalo-Orden J.M., Ginja M., (2022) Effects of testosterone and exercise training on bone microstructure of rats Veterinary World 15 :627-633. ISSN: 22310916. doi: 10.14202/vetworld.2022.627-633.
Expression of LncRNAs in HPV-induced Carcinogenesis and Cancer Cachexia: A Study in K14-HPV16 Mice
Dias T.R., Santos J.M.O., Estêvão D., Costa N.R., Mestre V.F., Medeiros-Fonseca B., Bastos M.M.S.M., Oliveira P.A., Gil Da Costa R.M., Medeiros R., (2022) Expression of LncRNAs in HPV-induced Carcinogenesis and Cancer Cachexia: A Study in K14-HPV16 Mice Anticancer Research 42 :2443-2460. ISSN: 17917530. doi: 10.21873/anticanres.15723.
Food Toxicology and Food Safety: Report of the 3rd International Electronic Conference on Foods: Food, Microbiome, and Health—A Celebration of the 10th Anniversary of Foods’ Impact on Our Wellbeing
Lachenmeier D.W., Oliveira P.A., Fabiszewska A.U., Soares C.M.D., Kim J.H., (2022) Food Toxicology and Food Safety: Report of the 3rd International Electronic Conference on Foods: Food, Microbiome, and Health—A Celebration of the 10th Anniversary of Foods’ Impact on Our Wellbeing Foods 11 (4099). ISSN: 23048158. doi: 10.3390/foods11244099.
Gallic Acid–Triethylene Glycol Aptadendrimers Synthesis, Biophysical Characterization and Cellular Evaluation
Miranda A., Lopez-Blanco R., Lopes-Nunes J., Melo A.M., Campello M.P.C., Paulo A., Oliveira M.C., Mergny J.L., Oliveira P.A., Fernandez-Megia E., Cruz C., (2022) Gallic Acid–Triethylene Glycol Aptadendrimers Synthesis, Biophysical Characterization and Cellular Evaluation Pharmaceutics 14 (2456). ISSN: 19994923. doi: 10.3390/pharmaceutics14112456.
Genoprotection and metabolic benefits of marine macroalgae - Insights into the concept of functional foods through direct and indirect consumption
Marques A., Ferreira J., Cerqueda-Pacheco A., Pereira V., Abreu H., Pereira R., Pires M.J., Seixas F., Oliveira P., Gaivão I., Pacheco M., (2022) Genoprotection and metabolic benefits of marine macroalgae - Insights into the concept of functional foods through direct and indirect consumption Food Bioscience 47 (101649). ISSN: 22124306. doi: 10.1016/j.fbio.2022.101649.
Long-Term Aerobic Training Improves Mitochondrial and Antioxidant Function in the Liver of Wistar Rats Preventing Hepatic Age-Related Function Decline
Silva M.G., Nunes P., Oliveira P., Ferreira R., Fardilha M., Moreira-Gonçalves D., Duarte J.A., Oliveira M.M., Peixoto F., (2022) Long-Term Aerobic Training Improves Mitochondrial and Antioxidant Function in the Liver of Wistar Rats Preventing Hepatic Age-Related Function Decline Biology 11 (1750). ISSN: 20797737. doi: 10.3390/biology11121750.
Mast Cells and their Role in Health and Disease
Faustino A.I., Oliveira P.A., (2022) Mast Cells and their Role in Health and Disease Mast Cells and their Role in Health and Disease :1-129. doi: 10.52305/GPJW5150.
Mutant p53 reactivator SLMP53-2 hinders ultraviolet B radiation-induced skin carcinogenesis
Loureiro J.B., Ribeiro R., Nazareth N., Ferreira T., Lopes E.A., Gama A., Machuqueiro M., Alves M.G., Marabini L., Oliveira P.A., Santos M.M.M., Saraiva L., (2022) Mutant p53 reactivator SLMP53-2 hinders ultraviolet B radiation-induced skin carcinogenesis Pharmacological Research 175 (106026). ISSN: 10961186. doi: 10.1016/j.phrs.2021.106026.
Pulegone and Eugenol Oral Supplementation in Laboratory Animals: Results from Acute and Chronic Studies
Ribeiro-Silva C.M., Faustino-Rocha A.I., Gil da Costa R.M., Medeiros R., Pires M.J., Gaivão I., Gama A., Neuparth M.J., Barbosa J.V., Peixoto F., Magalhães F.D., Bastos M.M.S.M., Oliveira P.A., (2022) Pulegone and Eugenol Oral Supplementation in Laboratory Animals: Results from Acute and Chronic Studies Biomedicines 10 (2595). ISSN: 22279059. doi: 10.3390/biomedicines10102595.
Supplementation of an Anthocyanin-Rich Elderberry (Sambucus nigra L.) Extract in FVB/n Mice: A Healthier Alternative to Synthetic Colorants
Azevedo T., Ferreira T., Ferreira J., Teixeira F., Ferreira D., Silva-Reis R., Neuparth M.J., Pires M.J., Pinto M.d.L., Gil da Costa R.M., Bastos M.M.S.M., Medeiros R., Félix L., Venâncio C., Dias M.I., Gaivão I., Barros L., Oliveira P.A., (2022) Supplementation of an Anthocyanin-Rich Elderberry (Sambucus nigra L.) Extract in FVB/n Mice: A Healthier Alternative to Synthetic Colorants Applied Sciences (Switzerland) 12 (11928). ISSN: 20763417. doi: 10.3390/app122311928.
Tracking Prostate Carcinogenesis over Time through Urine Proteome Profiling in an Animal Model: An Exploratory Approach
Moreira-Pais A., Nogueira-Ferreira R., Reis S., Aveiro S., Barros A., Melo T., Matos B., Duarte J.A., Seixas F., Domingues P., Amado F., Fardilha M., Oliveira P.A., Ferreira R., Vitorino R., (2022) Tracking Prostate Carcinogenesis over Time through Urine Proteome Profiling in an Animal Model: An Exploratory Approach International Journal of Molecular Sciences 23 (7560). ISSN: 14220067. doi: 10.3390/ijms23147560.
Validation of the Rat Model of Prostate Cancer: Correlating Seminal Vesicle Lesions With Dorsolateral Prostate Lesions
Nascimento-Gonçalves E., Seixas F., Oliveira B.M.M., Teiga-Teixeira J.E., Faustino-Rocha A.I., Colaço B., Ferreira R., Oliveira P.A., (2022) Validation of the Rat Model of Prostate Cancer: Correlating Seminal Vesicle Lesions With Dorsolateral Prostate Lesions In Vivo 36 :2662-2668. ISSN: 17917549. doi: 10.21873/invivo.13001.
Wild Boars (Sus scrofa, L. 1758) from Castile and Leon Region (Spain): A Histopathology Survey
Jota Baptista C., Gonzalo-Orden J.M., Merino-Goyenechea L.J., Oliveira P.A., Seixas F., (2022) Wild Boars (Sus scrofa, L. 1758) from Castile and Leon Region (Spain): A Histopathology Survey Animals 12 (3282). ISSN: 20762615. doi: 10.3390/ani12233282.
Wildlife Forensic Sciences: A Tool to Nature Conservation towards a One Health Approach
Jota Baptista C., Seixas F., Gonzalo-Orden J.M., Oliveira P.A., (2022) Wildlife Forensic Sciences: A Tool to Nature Conservation towards a One Health Approach Forensic Sciences 2 :808-817. ISSN: 26736756. doi: 10.3390/forensicsci2040058.
An overview of the latest in state-of-the-art murine models for prostate cancer
Nascimento-Gonçalves E., Seixas F., Ferreira R., Colaço B., Parada B., Oliveira P.A., (2021) An overview of the latest in state-of-the-art murine models for prostate cancer Expert Opinion on Drug Discovery 16 :1349-1364. ISSN: 1746045X. doi: 10.1080/17460441.2021.1943354.
Animal Models in Pharmacology: A Brief History Awarding the Nobel Prizes for Physiology or Medicine
Baptista C.V.J., Faustino-Rocha A.I., Oliveira P.A., (2021) Animal Models in Pharmacology: A Brief History Awarding the Nobel Prizes for Physiology or Medicine Pharmacology 106 :356-368. ISSN: 14230313. doi: 10.1159/000516240.
Animal models of colorectal cancer: From spontaneous to genetically engineered models and their applications
Nascimento-Gonçalves E., Mendes B.A.L., Silva-Reis R., Faustino-Rocha A.I., Gama A., Oliveira P.A., (2021) Animal models of colorectal cancer: From spontaneous to genetically engineered models and their applications Veterinary Sciences 8 (59). ISSN: 23067381. doi: 10.3390/vetsci8040059.
Aptamer-functionalized gold nanoparticles for drug delivery to gynecological carcinoma cells
Lopes-Nunes J., Agonia A.S., Rosado T., Gallardo E., Palmeira-De-oliveira R., Palmeira-De-oliveira A., Martinez-De-oliveira J., Fonseca-Moutinho J., Campello M.P.C., Paiva A., Paulo A., Vulgamott A., Ellignton A.D., Oliveira P.A., Cruz C., (2021) Aptamer-functionalized gold nanoparticles for drug delivery to gynecological carcinoma cells Cancers 13 (4038). ISSN: 20726694. doi: 10.3390/cancers13164038.
Chronic exercise training attenuates prostate cancer-induced molecular remodelling in the testis
Matos B., Patrício D., Henriques M.C., Freitas M.J., Vitorino R., Duarte I.F., Howl J., Oliveira P.A., Seixas F., Duarte J.A., Ferreira R., Fardilha M., (2021) Chronic exercise training attenuates prostate cancer-induced molecular remodelling in the testis Cellular Oncology 44 :311-327. ISSN: 22113436. doi: 10.1007/s13402-020-00567-9.
Differential incidence of tongue base cancer in male and female hpv16-transgenic mice: role of female sex hormone receptors
Neto C.P.d.O., Medeiros-Fonseca B., Estêvão D., Mestre V.F., Costa N.R., de Andrade F.E., Oliveira P.A., Bastos M.M.S.M., Medeiros R., Assis D., Félix A., Lopes F.F., Gil da Costa R.M., Brito H.O., Brito L.M.O., (2021) Differential incidence of tongue base cancer in male and female hpv16-transgenic mice: role of female sex hormone receptors Pathogens 10 (1224). ISSN: 20760817. doi: 10.3390/pathogens10101224.
Experimental models for studying HPV-positive and HPV-negative penile cancer: New tools for an old disease
Medeiros-Fonseca B., Cubilla A., Brito H., Martins T., Medeiros R., Oliveira P., Gil Da Costa R.M., (2021) Experimental models for studying HPV-positive and HPV-negative penile cancer: New tools for an old disease Cancers 13 (460) :1-15. ISSN: 20726694. doi: 10.3390/cancers13030460.
G-quadruplex-based drug delivery systems for cancer therapy
Lopes-Nunes J., Oliveira P.A., Cruz C., (2021) G-quadruplex-based drug delivery systems for cancer therapy Pharmaceuticals 14 (671). ISSN: 14248247. doi: 10.3390/ph14070671.
Influence of overliming vineyard acid soils on the macro-nutritional status of grapevines
Olego M.A., Quiroga M.J., Cuesta M., Oliveira P.A., Garzón-Jimeno J.E., (2021) Influence of overliming vineyard acid soils on the macro-nutritional status of grapevines Spanish Journal of Agricultural Research 19 (e0903). ISSN: 21719292. doi: 10.5424/sjar/2021193-17638.
Pteridium spp. and Bovine Papillomavirus: Partners in Cancer
Medeiros-Fonseca B., Abreu-Silva A.L., Medeiros R., Oliveira P.A., Gil da Costa R.M., (2021) Pteridium spp. and Bovine Papillomavirus: Partners in Cancer Frontiers in Veterinary Science 8 (758720). ISSN: 22971769. doi: 10.3389/fvets.2021.758720.
Refinement of animal model of colorectal carcinogenesis through the definition of novel humane endpoints
Silva-Reis R., Faustino-Rocha A.I., Gonçalves M., Ribeiro C.C., Ferreira T., Ribeiro-Silva C., Gonçalves L., Antunes L., Venâncio C., Ferreira R., Gama A., Oliveira P.A., (2021) Refinement of animal model of colorectal carcinogenesis through the definition of novel humane endpoints Animals 11 (985). ISSN: 20762615. doi: 10.3390/ani11040985.
Sarcopenia versus cancer cachexia: the muscle wasting continuum in healthy and diseased aging
Moreira-Pais A., Ferreira R., Oliveira P.A., Duarte J.A., (2021) Sarcopenia versus cancer cachexia: the muscle wasting continuum in healthy and diseased aging Biogerontology 22 :459-477. ISSN: 15736768. doi: 10.1007/s10522-021-09932-z.
The influence of Castanea sativa Mill. flower extract on hormonally and chemically induced prostate cancer in a rat model
Nascimento-Gonçalves E., Seixas F., Silva M., Fardilha M., Ferreira R., Neuparth M.J., Faustino-Rocha A.I., Colaço B., Venâncio C., Barros L., Ferreira I.C.F.R., Oliveira M.M., Peixoto F., Rosa E., Oliveira P.A., (2021) The influence of Castanea sativa Mill. flower extract on hormonally and chemically induced prostate cancer in a rat model Food and Function 12 :2631-2643. ISSN: 2042650X. doi: 10.1039/d1fo00029b.
The red seaweed grateloupia turuturu prevents epidermal dysplasia in hpv16-transgenic mice
Almeida J., Ferreira T., Santos S., Pires M.J., da Costa R.M.G., Medeiros R., Bastos M.M.S.M., Neuparth M.J., Faustino-Rocha A.I., Abreu H., Pereira R., Pacheco M., Gaivão I., Rosa E., Oliveira P.A., (2021) The red seaweed grateloupia turuturu prevents epidermal dysplasia in hpv16-transgenic mice Nutrients 13 (4529). ISSN: 20726643. doi: 10.3390/nu13124529.
Toxicological and anti-tumor effects of a linden extract (: Tilia platyphyllos Scop.) in a HPV16-transgenic mouse model
Ferreira T., Nascimento-Gonçalves E., Macedo S., Borges I., Gama A., M. Gil Da Costa R., Neuparth M.J., Lanzarin G., Venâncio C., Félix L., Gaivão I., Alvarado A., Pires M.J., Bastos M.M.S.M., Medeiros R., Nogueira A., Barros L., Ferreira I.C.F.R., Rosa E., Oliveira P.A., (2021) Toxicological and anti-tumor effects of a linden extract (: Tilia platyphyllos Scop.) in a HPV16-transgenic mouse model Food and Function 12 :4005-4014. ISSN: 2042650X. doi: 10.1039/d1fo00225b.
An Overview of Current Alternative Models for Use in the Context of Prostate Cancer Research
Nascimento-Gonçalves E., Ferreira R., Oliveira P.A., Colaço B.J.A., (2020) An Overview of Current Alternative Models for Use in the Context of Prostate Cancer Research ATLA Alternatives to Laboratory Animals 48 :58-69. ISSN: 26323559. doi: 10.1177/0261192920929701.
Dietary supplementation with chestnut (Castanea sativa) reduces abdominal adiposity in FVB/n mice: A preliminary study
Rodrigues P., Ferreira T., Nascimento-Gonçalves E., Seixas F., da Costa R.M.G., Martins T., Neuparth M.J., Pires M.J., Lanzarin G., Félix L., Venâncio C., Ferreira I.C.F.R., Bastos M.M.S.M., Medeiros R., Gaivão I., Rosa E., Oliveira P.A., (2020) Dietary supplementation with chestnut (Castanea sativa) reduces abdominal adiposity in FVB/n mice: A preliminary study Biomedicines 8 (75). ISSN: 22279059. doi: 10.3390/biomedicines8040075.
Elucidating the mechanisms of action of parecoxib in the MG-63 osteosarcoma cell line
Lemos S., Sampaio-Marques B., Ludovico P., Gaivaõ I., Palmeira C., Martins G., Peixoto F., Pinto-Leite R., Oliveira P., (2020) Elucidating the mechanisms of action of parecoxib in the MG-63 osteosarcoma cell line Anti-Cancer Drugs 31 :507-517. ISSN: 14735741. doi: 10.1097/CAD.0000000000000901.
Histopathological Features of Organs in a Rat Model of Mammary Carcinogenesis: A Reference Database
Vala H., Vasconcelos-Nóbrega C., Gama A., Ferreira R., Oliveira P.A., Faustino-Rocha A.I., (2020) Histopathological Features of Organs in a Rat Model of Mammary Carcinogenesis: A Reference Database Revista Electronica de Veterinaria 21 :12-24. ISSN: 16957504.
HPV infection as a risk factor for atherosclerosis: A connecting hypothesis
Reis D.R.A., Medeiros-Fonseca B., Costa J.M., de Oliveira Neto C.P., Gil da Costa R.M., Oliveira P.A., Medeiros R., Bastos M.M.S.M., Brito H.O., Brito L.M.O., (2020) HPV infection as a risk factor for atherosclerosis: A connecting hypothesis Medical Hypotheses 144 (109979). ISSN: 15322777. doi: 10.1016/j.mehy.2020.109979.
HPV16 induces penile intraepithelial neoplasia and squamous cell carcinoma in transgenic mice: first mouse model for HPV-related penile cancer.
Medeiros-Fonseca, B.; Mestre, V.F.; Estêvão, D.; Sánchez, D.F.; Cañete-Portillo, S.; Fernández-Nestosa, M.J.; Casaca, F.; Silva, S.; Brito, H.; Félix, A.; Medeiros, R.; Colaço, B.; Oliveira, P.A.; Bastos, M.M.S.M.; Nelson, P.S.; Vakar-Lopez, F.; Gaivão, I.; Brito, L.; Lopes, C.; Cubilla, A.L.; Gil da Costa, R.M. (2020) HPV16 induces penile intraepithelial neoplasia and squamous cell carcinoma in transgenic mice: first mouse model for HPV-related penile cancer. JOURNAL OF PATHOLOGY 251 (4) :411-419. doi: 10.1002/path.5475.. (Impact factor, Quartile: 6.021, Q1).
HPV16 is sufficient to induce squamous cell carcinoma specifically in the tongue base in transgenic mice
Mestre V.F., Medeiros-Fonseca B., Estêvão D., Casaca F., Silva S., Félix A., Silva F., Colaço B., Seixas F., Bastos M.M.S.M., Lopes C., Medeiros R., Oliveira P.A., Gil da Costa R.M., (2020) HPV16 is sufficient to induce squamous cell carcinoma specifically in the tongue base in transgenic mice Journal of Pathology 251 :4-11. ISSN: 10969896. doi: 10.1002/path.5387.
Human papillomavirus 16-transgenic mice as a model to study cancer-associated cachexia
da Silva S.P., Santos J.M.O., Mestre V.F., Medeiros-Fonseca B., Oliveira P.A., Bastos M.M.S.M., Gil da Costa R.M., Medeiros R., (2020) Human papillomavirus 16-transgenic mice as a model to study cancer-associated cachexia International Journal of Molecular Sciences 21 (5020) :1-17. ISSN: 14220067. doi: 10.3390/ijms21145020.
P53 in skin cancer: From a master player to a privileged target for prevention and therapy
Loureiro J.B., Abrantes M., Oliveira P.A., Saraiva L., (2020) P53 in skin cancer: From a master player to a privileged target for prevention and therapy Biochimica et Biophysica Acta - Reviews on Cancer 1874 (188438). ISSN: 18792561. doi: 10.1016/j.bbcan.2020.188438.
Ptaquiloside from bracken (: Pteridium spp.) promotes oral carcinogenesis initiated by HPV16 in transgenic mice
Gil Da Costa R.M., Neto T., Estêvão D., Moutinho M., Félix A., Medeiros R., Lopes C., Bastos M.M.S.M., Oliveira P.A., (2020) Ptaquiloside from bracken (: Pteridium spp.) promotes oral carcinogenesis initiated by HPV16 in transgenic mice Food and Function 11 :3298-3305. ISSN: 2042650X. doi: 10.1039/d0fo00207k.
Ultrasonographic Follow-up of the Multistep Protocol for Prostate Cancer Induction in Wistar Rats
Faustino-Rocha A.I., Seixas F., Ferreira R., Silva J., Pires M.J., Fardilha M., Ginja M., Oliveira P.A., (2020) Ultrasonographic Follow-up of the Multistep Protocol for Prostate Cancer Induction in Wistar Rats In Vivo 34 :1797-1803. ISSN: 17917549. doi: 10.21873/invivo.11974.
Anatomy and imaging of rat prostate: Practical monitoring in experimental cancer-induced protocols
Ginja M., Pires M.J., Gonzalo-Orden J.M., Seixas F., Correia-Cardoso M., Ferreira R., Fardilha M., Oliveira P.A., Faustino-Rocha A.I., (2019) Anatomy and imaging of rat prostate: Practical monitoring in experimental cancer-induced protocols Diagnostics 9 (68). ISSN: 20754418. doi: 10.3390/diagnostics9030068.
Dietary supplementation with the red seaweed porphyra umbilicalis protects against DNA damage and pre-malignant dysplastic skin lesions in HPV-transgenic mice
Santos S., Ferreira T., Almeida J., Pires M.J., Colaço A., Lemos S., Da Costa R.M.G., Medeiros R., Bastos M.M.S.M., Neuparth M.J., Abreu H., Pereira R., Pacheco M., Gaivão I., Rosa E., Oliveira P.A., (2019) Dietary supplementation with the red seaweed porphyra umbilicalis protects against DNA damage and pre-malignant dysplastic skin lesions in HPV-transgenic mice Marine Drugs 17 (615). ISSN: 16603397. doi: 10.3390/md17110615.
Dimethylaminoparthenolide reduces the incidence of dysplasia and ameliorates a wasting syndrome in HPV16-transgenic mice
Santos J.M.O., Moreira-Pais A., Neto T., Peixoto da Silva S., Oliveira P.A., Ferreira R., Mendes J., Bastos M.M.S.M., Lopes C., Casaca F., Silva S., Sweeney C., Medeiros R., Gil da Costa R.M., (2019) Dimethylaminoparthenolide reduces the incidence of dysplasia and ameliorates a wasting syndrome in HPV16-transgenic mice Drug Development Research 80 :824-830. ISSN: 10982299. doi: 10.1002/ddr.21565.
Exercise training counteracts urothelia carcinoma-induced alterations in skeletal muscle mitochondria phospholipidome in an animal model.
Montero-Bullon, Javier-Fernando; Melo, Tânia; Ferreira, Rita; Padrão, Ana I.; Oliveira, Paula A.; Domingues, M. Rosário; Domingues, Pedro (2019) Exercise training counteracts urothelia carcinoma-induced alterations in skeletal muscle mitochondria phospholipidome in an animal model. SCIENTIFIC REPORTS 9 :13423. doi: 10.1038/s41598-019-49010-6. (Impact factor, Quartile: 4.011, Q1).
Exercise training counteracts urothelial carcinoma-induced alterations in skeletal muscle mitochondria phospholipidome in an animal model
Montero-Bullon J.F., Melo T., Ferreira R., Padrão A.I., Oliveira P.A., Domingues M.R.M., Domingues P., (2019) Exercise training counteracts urothelial carcinoma-induced alterations in skeletal muscle mitochondria phospholipidome in an animal model Scientific Reports 9 (13423). ISSN: 20452322. doi: 10.1038/s41598-019-49010-6.
Exercise training impacts cardiac mitochondrial proteome remodeling in murine urothelial carcinoma
Ferreira R., Neuparth M.J., Nogueira-Ferreira R., Magalhães S., Aroso M., Bovolini J.A., Santos L.L., Oliveira P., Vitorino R., Moreira-Gonçalves D., (2019) Exercise training impacts cardiac mitochondrial proteome remodeling in murine urothelial carcinoma International Journal of Molecular Sciences 20 (127). ISSN: 14220067. doi: 10.3390/ijms20010127.
One year of exercise training promotes distinct adaptations in right and left ventricle of female Sprague-Dawley rats
Nogueira-Ferreira R., Ferreira R., Padrão A.I., Oliveira P., Santos M., Kavazis A.N., Vitorino R., Moreira-Gonçalves D., (2019) One year of exercise training promotes distinct adaptations in right and left ventricle of female Sprague-Dawley rats Journal of Physiology and Biochemistry 75 :561-572. ISSN: 18778755. doi: 10.1007/s13105-019-00705-4.
Re: A study in a rat initiation-promotion bladder tumour model demonstrated no promoter/progressor potential of dapagliflozin
Oliveira P., Seixas F., (2019) Re: A study in a rat initiation-promotion bladder tumour model demonstrated no promoter/progressor potential of dapagliflozin Regulatory Toxicology and Pharmacology 106 :346. ISSN: 10960295. doi: 10.1016/j.yrtph.2019.05.010.
Studying humane endpoints in a rat model of mammary carcinogenesis
Faustino-Rocha A.I., Ginja M., Ferreira R., Oliveira P.A., (2019) Studying humane endpoints in a rat model of mammary carcinogenesis Iranian Journal of Basic Medical Sciences 22 :643-649. ISSN: 20083874. doi: 10.22038/ijbms.2019.33331.7957.
The cyclooxigenase-2 inhibitor parecoxib prevents epidermal dysplasia in HPV16-transgenic mice: efficacy and safety observations
Ferreira T., Campos S., Silva M.G., Ribeiro R., Santos S., Almeida J., Pires M.J., da Costa R.M.G., Córdova C., Nogueira A., Neuparth M.J., Medeiros R., Bastos M.M.d.S.M., Gaivão I., Peixoto F., Oliveira M.M., Oliveira P.A., (2019) The cyclooxigenase-2 inhibitor parecoxib prevents epidermal dysplasia in HPV16-transgenic mice: efficacy and safety observations International Journal of Molecular Sciences 20 (3902). ISSN: 14220067. doi: 10.3390/ijms20163902.
The relevance of Rattus norvegicus in mammary cancer research.
Alvarado, A.; Faustino-Rocha, A.I; Colaço, B.; Oliveira, P.A. (2019) The relevance of Rattus norvegicus in mammary cancer research. In, Alvarado, A., Faustino-Rocha, A. (Eds). Rattus norvegicus - A Review and Directions for Research. Nova Science Publishers. Chapter 2. ISBN: 978-1-53614-685-1.
Assessment of the exposure to heavy metals and arsenic in captive and freeliving black kites (Milvus migrans) nesting in Portugal.
Carneiro, M.; Oliveira, P.A.; Brandão, R.; Soeiro, V.; Pires, M.J.; Lavin, S.; Colaço, B. (2018) Assessment of the exposure to heavy metals and arsenic in captive and freeliving black kites (Milvus migrans) nesting in Portugal. Ecotoxicology And Environmental Safety 160 :191-196. doi: 10.1016/j.ecoenv.2018.05.040. (Impact factor, Quartile: 3.974, Q1).
Curcumin and Rutin Down-regulate Cyclooxygenase-2 and Reduce Tumor-associated Inflammation in HPV16-Transgenic Mice.
Moutinho, M.; Aragão, S.; Carmo, D.; Casaca, F.; Silva, S.; Ribeiro, J.; Sousa, H.; Pires, I.; Queiroga, F.; Colaço, B.; Medeiros, R.; Oliveira, P.A.; Lopes, C.; Bastos, M.; Gil da Costa, R. (2018) Curcumin and Rutin Down-regulate Cyclooxygenase-2 and Reduce Tumor-associated Inflammation in HPV16-Transgenic Mice. Anticancer Research 38 :1461-1466. doi: 10.21873/anticanres.12371. (Impact factor, Quartile: 1.865, Q4).
Exercise training protects against cancer-induced cardiac remodeling in an animal model of urothelial carcinoma.
Padrao, Ana Isabel; Nogueira-Ferreira, Rita; Vitorino, Rui; Carvalho, Dulce; Correia, Catarina; Neuparth, Maria Joao; Pires, Maria Joao; Faustino-Rocha, Ana Isabel; Santos, Lucio Lara; Oliveira, Paula Alexandra; Duarte, Jose Alberto; Moreira-Goncalves, Daniel; Ferreira, Rita (2018) Exercise training protects against cancer-induced cardiac remodeling in an animal model of urothelial carcinoma. Archives Of Biochemistry And Biophysics 645 :43435. doi: 10.1016/j.abb.2018.03.013. (Impact factor, Quartile: 3.118, Q2).
Exercise Training-induced Modulation in Microenvironment of Rat Mammary Neoplasms.
Figueira, A.C.C.; Figueira, M.C.; Silva, C.; Padrão, A.; Oliveira, P.A.; Ferreira, R.P.; Duarte, J.A. (2018) Exercise Training-induced Modulation in Microenvironment of Rat Mammary Neoplasms. INTERNATIONAL JOURNAL OF SPORTS MEDICINE 39 (12) :885-892. doi: 10.1055/a-0660-0198. (Impact factor, Quartile: 2.453, Q2).
Expression profile of microRNA-146a along HPV-induced multistep carcinogenesis: a study in HPV16 transgenic mice.
Araujo, Rita; Santos, Joana M. O.; Fernandes, Mara; Dias, Francisca; Sousa, Hugo; Ribeiro, Joana; Bastos, Margarida M. S. M.; Oliveira, Paula A.; Carmo, Diogo; Casaca, Fatima; Silva, Sandra; Medeiros, Rui; Gil da Costa, Rui M. (2018) Expression profile of microRNA-146a along HPV-induced multistep carcinogenesis: a study in HPV16 transgenic mice. Journal Of Cancer Research And Clinical Oncology 144 (2) :241:248. doi: 10.1007/s00432-017-2549-5. (Impact factor, Quartile: 3.282, Q2).
Intense Pulsed Light: Friend or Foe? Molecular Evidence to Clarify Doubts.
Ferreira, Liliana; Vitorino, Rui; Neuparth, Maria Joao; Rodrigues, David; Gama, Adelina; Faustino-Rocha, Ana I.; Ferreira, Rita; Oliveira, Paula A (2018) Intense Pulsed Light: Friend or Foe? Molecular Evidence to Clarify Doubts. Anticancer Research 38 (2) :779-786. doi: 10.21873/anticanres.12284. (Impact factor, Quartile: 1.865, Q4).
Laurus nobilis (laurel) aqueous leaf extract's toxicological and anti-tumor activities in HPV16-transgenic mice.
Medeiros-Fonseca, B; Mestre, VF; Colaço, B; Pires, MJ; Martins, T; Gil da Costa, RM; Neuparth, MJ; Medeiros, R; Moutinho, MSS; Dias, MI; Barros, L; Bastos, MMSM; Félix, L; Venâncio, C; Ferreira, ICFR; Antunes, LM; Oliveira, PA. (2018) Laurus nobilis (laurel) aqueous leaf extract's toxicological and anti-tumor activities in HPV16-transgenic mice. FOOD & FUNCTION 9 :4419-4428. doi: 10.1039/c8fo00783g. (Impact factor, Quartile: 3.289, Q1).
Modelling human prostate cancer: Rat models.
Nascimento-Goncalves, Elisabete; Faustino-Rocha, Ana I.; Seixas, Fernanda; Ginja, Mario; Colaço, Bruno; Ferreira, Rita; Fardilha, Margarida; Oliveira, Paula A. (2018) Modelling human prostate cancer: Rat models. Life Sciences 203 :210-224. doi: 10.1016/j.lfs.2018.04.014. (Impact factor, Quartile: 3.234, Q2).
Ozone therapy prevents the onset of dysplasia in HPV16-transgenic mice-A pre-clinical efficacy and safety analysis.
Peirone, C.; Mestre, V. F.; Medeiros-Fonseca, B.; Colaço, B.; Pires, M. J.; Martins, T.; Gil da Costa, R. M.; Neuparth, M. J.; Medeiros, R.; Bastos, M. M. S. M.; Marques-Magallanes, J. A.; Oliveira, P. A. (2018) Ozone therapy prevents the onset of dysplasia in HPV16-transgenic mice-A pre-clinical efficacy and safety analysis. Biomedicine & Pharmacotherapy 104 :275-279. doi: 10.1016/j.biopha.2018.05.018. (Impact factor, Quartile: 3.457, Q2).
Potential effects of sulforaphane to fight obesity.
Martins, Tânia; Colaço, Bruno; Venâncio, Carlos; Pires, Maria J.; Oliveira, Paula A.; Rosa, Eduardo; Antunes, Luis M. (2018) Potential effects of sulforaphane to fight obesity. Journal Of The Science Of Food And Agriculture 98 (8) :2837-2844. doi: 10.1002/jsfa.8898. (Impact factor, Quartile: 2.379, Q1).
A Contrast Enhanced Ultrasonographic Study About the Impact of Long term Exercise Training on Mammary Tumor Vascularization.
Faustino Rocha, AIF, Gama, A, Oliveira, PA, Vanderperren, K, Saunders, JH, Pires, MJ, Ferreira, R, Ginja, M (2017) A Contrast Enhanced Ultrasonographic Study About the Impact of Long term Exercise Training on Mammary Tumor Vascularization. Journal Of Ultrasound In Medicine 36 :2459-2466. ISSN: 0278-4297. doi: 10.1002/jum.14287. (Impact factor, Quartile: 1.547, Q3).
A spontaneous high-grade undifferentiated mammary carcinoma in a seven-week-old female rat.
Faustino-Rocha, AI, Gama, A, Oliveira, PA, Alvarado, A, Ferreira, R, Ginja, M (2017) A spontaneous high-grade undifferentiated mammary carcinoma in a seven-week-old female rat. Experimental And Toxicologic Pathology 69 :241-244. ISSN: 0940-2993. doi: 10.1016/j.etp.2017.01.006. (Impact factor, Quartile: 1.975, Q2).
Antihistamines as promising drugs in cancer therapy.
Faustino-Rocha, AI, Ferreira, R, Gama, A, Oliveira, PA, Ginja, M (2017) Antihistamines as promising drugs in cancer therapy. Life Sciences 172 :27-41. ISSN: 0024-3205. doi: 10.1016/j.lfs.2016.12.008. (Impact factor, Quartile: 2.963, Q2).
Effects of exercise training on breast cancer metastasis in a rat model.
Alvarado, A, da Costa, RMG, Faustino-Rocha, AI, Ferreira, R, Lopes, C, Oliveira, PA, Colaço, B (2017) Effects of exercise training on breast cancer metastasis in a rat model. International Journal Of Experimental Pathology 98 :40-46. ISSN: 0959-9673. doi: 10.1111/iep.12225. (Impact factor, Quartile: 1.78, Q3).
Effects of lifelong exercise training on mammary tumorigenesis induced by MNU in female Sprague-Dawley rats.
Faustino-Rocha, AI, Gama, A, Oliveira, PA, Alvarado, A, Neuparth, MJ, Ferreira, R, Ginja, M (2017) Effects of lifelong exercise training on mammary tumorigenesis induced by MNU in female Sprague-Dawley rats. Clinical And Experimental Medicine 17 :151-160. ISSN: 1591-8890. doi: 10.1007/s10238-016-0419-0. (Impact factor, Quartile: 2.919, Q2).
Experimental mammary carcinogenesis - Rat models.
Alvarado, A, Faustino-Rocha, AI, Colaço, B, Oliveira, PA (2017) Experimental mammary carcinogenesis - Rat models. Life Sciences 173 :116-134. ISSN: 0024-3205. doi: 10.1016/j.lfs.2017.02.004. (Impact factor, Quartile: 2.963, Q2).
HPV16 induces a wasting syndrome in transgenic mice: Amelioration by dietary polyphenols via NF-kappa B inhibition.
da Costa, RMG, Aragao, S, Moutinho, M, Alvarado, A, Carmo, D, Casaca, F, Silva, S, Ribeiro, J, Sousa, H, Ferreira, R, Nogueira-Ferreira, R, Pires, MJ, Colaço, B, Medeiros, R, Venancio, C, Oliveira, MM, Bastos, MMSM, Lopes, C, Oliveira, PA (2017) HPV16 induces a wasting syndrome in transgenic mice: Amelioration by dietary polyphenols via NF-kappa B inhibition. Life Sciences 169 :19-Nov. ISSN: 0024-3205. doi: 10.1016/j.lfs.2016.10.031. (Impact factor, Quartile: 2.963, Q2).
Implementation of Human Endpoints in a Urinary Bladder Carcinogenesis Study in Rats.
Oliveira, M, Nascimento-Goncalves, E, Silva, J, Oliveira, PA, Ferreira, R, Antunes, L, Arantes-Rodrigues, R, Faustino-Rocha, AI (2017) Implementation of Human Endpoints in a Urinary Bladder Carcinogenesis Study in Rats. In Vivo 31 :1073-1080. ISSN: 0258-851X. doi: 10.21873/invivo.11172. (Impact factor, Quartile: 0.953, Q4).
Mast Cells in Mammary Carcinogenesis: Host or Tumor Supporters?
Faustino-Rocha, AI, Gama, A, Neuparth, MJ, Oliveira, PA, Ferreira, R, Ginja, M (2017) Mast Cells in Mammary Carcinogenesis: Host or Tumor Supporters? Anticancer Research 37 :1013-1021. ISSN: 0250-7005. doi: 10.21873/anticanres.11411. (Impact factor, Quartile: 1.937, Q3).
Modulation of mammary tumor vascularization by mast cells: Ultrasonographic and histopathological approaches.
Faustino-Rocha, AI, Gama, A, Oliveira, PA, Katrien, VE, Saunders, JH, Pires, MJ, Ferreira, R, Ginja, M (2017) Modulation of mammary tumor vascularization by mast cells: Ultrasonographic and histopathological approaches. Life Sciences 176 :35-41. ISSN: 0024-3205. doi: 10.1016/j.lfs.2017.03.013. (Impact factor, Quartile: 2.963, Q2).
Prognostic factors in MNU and DMBA-induced mammary tumors in female rats.
Alvarado, A, Lopes, AC, Faustino-Rocha, AI, Cabrita, AMS, Ferreira, R, Oliveira, PA, Colaço, B (2017) Prognostic factors in MNU and DMBA-induced mammary tumors in female rats. Pathology Research And Practice 213 :441-446. ISSN: 0344-0338. doi: 10.1016/j.prp.2017.02.014. (Impact factor, Quartile: 1.543, Q3).
Regulation of miRNA-146a and miRNA-150 Levels by Celecoxib in Premalignant Lesions of K14-HPV16 Mice.
Da Costa, RMG, Araujo, R, Santos, JMO, Fernandes, M, Neto, T, Sousa, H, Ribeiro, J, Bastos, MMSM, Oliveira, PA, Carmo, D, Casaca, F, Silva, S, Lopes, C, Medeiros, R (2017) Regulation of miRNA-146a and miRNA-150 Levels by Celecoxib in Premalignant Lesions of K14-HPV16 Mice. Anticancer Research 37 :2913-2918. ISSN: 0250-7005. doi: 10.21873/anticanres.11644. (Impact factor, Quartile: 1.937, Q3).
Synergistic Effect of Carboplatin and Piroxicam on Two Bladder Cancer Cell Lines.
Silva, J, Arantes-Rodrigues, R, Pinto-Leite, R, Faustino-Rocha, AI, Fidalgo-Goncalves, L, Santos, L, Oliveira, PA (2017) Synergistic Effect of Carboplatin and Piroxicam on Two Bladder Cancer Cell Lines. Anticancer Research 37 :1737-1745. ISSN: 0250-7005. doi: 10.21873/anticanres.11506. (Impact factor, Quartile: 1.937, Q3).
Influence of overliming vineyard acid soils on the macro-nutritional status of grapevines.
Olego, M.A., Quiroga, M.J., Cuesta, M., Oliveira, P.A., Garzón-Jimeno, J.E. Influence of overliming vineyard acid soils on the macro-nutritional status of grapevines. Spanish Journal of Agricultural Research 19 (3), e0903, 15 pages. doi: 10.5424/sjar/2021193-17638. (Impact Factor, Quartile: 1.238 19 (3) (e0903). doi: 10.5424/sjar/2021193-17638. (Impact factor, Quartile: 1.238, Q3).

Projects

LivingSoiLL - Healthy Soil to Permanent Crops Living Labs
Running

Coordinator  /  Cristina Carlos
Start date  /  2024/06 Funding  /  European Commission - Horizon Europe Reference  /  GA 101157502

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Edu4OneHealth - Multifaceted intervention to improve antibiotic stewardship in Portugal: a One Health approach
Running

Coordinator  /  Teresa Herdeiro UTAD/CITAB Coordinator  /  Paula Oliveira
Start date  /  2023/03 Funding  /  FCT - PTDC Reference  /  2022.04568.PTDC

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Mush4Chol - Development of an efficient hypocholesterolemic formulation from mushroom bioresidues through a sustainable integrated strategy
Running

Coordinator  /  Sandrina Heleno UTAD/CITAB Coordinator  /  Paula Oliveira
Start date  /  2023/03 Funding  /  FCT - PTDC Reference  /  2022.08844.PTDC

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GREENValue - Valorisation of Resource Generation in Natural Space
Running

UTAD/CITAB Coordinator  /  José Laranjo
Start date  /  2022/07 Funding  /  COMPETE - REACT-EU Reference  /  POCI-07-62G4-FEDER-181589

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Vine & Wine PT - Driving Sustainable Growth Through Smart Innovation
Running

Coordinator  /  Jorge Dias UTAD/CITAB Coordinator  /  Raul Santos
Start date  /  2021/11 Funding  /  IAPMEI - PRR - Recovery and Resilience Plan / Mobilising Agendas Reference  /  C644866286-00000011

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VALORIZEBYPRODUCTS: Preclinical efficacy of sulforaphane or Brassica whole extract: a strategy to fight obesity and valorize Brassica byproduct
Concluded

Coordinator  /  Eduardo Rosa
Start date  /  2018/06 Funding  /  FCT/FEDER Reference  /  POCI-01-0145-FEDER-029152

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RUNaway - Running away from prostate cancer: Walking through the molecular basis of physical activity
Concluded

Coordinator  /  Paula Oliveira
Start date  /  2016/07 Funding  /  FCT/FEDER Reference  /  PTDC/DTP-DES/6077/2014

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SPLICETHER - Application of splicing approaches to exploit alternative therapies for Lysosomal Storage Diseases: in vitro and in vivo studies
Concluded

Coordinator  /  Sandra Alves UTAD/CITAB Coordinator  /  Paula Oliveira
Start date  /  2016/05 Funding  /  FCT/FEDER Reference  /  PTDC/BBB-BMD/6301/2014

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IBERPHENOL- Cooperative research network in the field of polyphenols and their industrial applications (INTERREG 0377_Iberphenol_6_E)
Concluded

Coordinator  /  Julián Rivas Gonzal UTAD/CITAB Coordinator  /  Eduardo Rosa
Start date  /  2015/10 Funding  /  INTERREG - POCTEP (Spain - Portugal) Reference  /  INTERREG 0377_Iberphenol_6_E

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O efeito cardioprotetor do exercício físico no cancro
Concluded

Coordinator  /  Rita Ferreira UTAD/CITAB Coordinator  /  Paula Oliveira
Start date  /  2014/01 Funding  /  FCT Reference  /  EXPL/DTP-DES/1010/2013

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Patents

Functionalized aqueous product with an extract of male flowers of castanea sativa mill. with hypocholesterolemic properties (115638)

Patent nº /  115638

Concession date / 2021-10-06

Researchers / Paula Oliveira