Amélia Maria Lopes Dias da Silva Full Member

BIO

Name: Amélia Maria Lopes Dias da Silva

Aggregation: Full Member

Orcid ID: 0000-0002-7524-9914

Email: amsilva@utad.pt

URL:

Phone:

Publications

Mediterranean essential oils as precious matrix components and active ingredients of lipid nanoparticles.
Carbone, C.; Martins-Gomes, C.; Caddeo, C.; Silva, A. M.; Musumeci, T.; Pignatello, R.; Puglisi, G.; Souto, E. B. (2018) Mediterranean essential oils as precious matrix components and active ingredients of lipid nanoparticles. International Journal Of Pharmaceutics 548 (1) :217-226. doi: 10.1016/j.ijpharm.2018.06.064. (Impact factor, Quartile: 3.862, Q1).

Repurposing itraconazole to the benefit of skin cancer treatment: A combined azole-DDAB nanoencapsulation strategy.
Carbone, C.; Martins-Gomes, C.; Pepe, V.; Silva, A. M.; Musumeci, T.; Puglisi, G.; Furneri, P. M.; Souto, E. B. (2018) Repurposing itraconazole to the benefit of skin cancer treatment: A combined azole-DDAB nanoencapsulation strategy. Colloids And Surfaces B-Biointerfaces 167 :337-344. doi: 10.1016/j.colsurfb.2018.04.031. (Impact factor, Quartile: 3.997, Q1).

Hansen solubility parameters (HSP) for prescreening formulation of solid lipid nanoparticles (SLN): in vitro testing of curcumin-loaded SLN in MCF-7 and BT-474 cell lines.
Doktorovova, Slavomira; Souto, Eliana B.; Silva, Amelia M. (2018) Hansen solubility parameters (HSP) for prescreening formulation of solid lipid nanoparticles (SLN): in vitro testing of curcumin-loaded SLN in MCF-7 and BT-474 cell lines. Pharmaceutical Development And Technology 23 (1) :96-105. doi: 10.1080/10837450.2017.1384491. (Impact factor, Quartile: 1.945, Q3).

Citrus reticulata Blanco peels as a source of antioxidant and anti-proliferative phenolic compounds.
Ferreira, Sandrine S.; Silva, Amelia M.; Nunes, Fernando M. (2018) Citrus reticulata Blanco peels as a source of antioxidant and anti-proliferative phenolic compounds. Industrial Crops And Products 111 :141-148. doi: 10.1016/j.indcrop.2017.10.009. (Impact factor, Quartile: 3.849, Q1).

Chemical characterization and bioactive properties of decoctions and hydroethanolic extracts of Thymus carnosus Boiss.
Martins-Gomes, Carlos; Taghouti, Meriem; Schaefer, Judith; Bunzel, Mirko; Silva, Amelia M.; Nunes, Fernando M. (2018) Chemical characterization and bioactive properties of decoctions and hydroethanolic extracts of Thymus carnosus Boiss. Journal Of Functional Foods 43 :154-164. doi: 10.1016/j.jff.2018.02.012. (Impact factor, Quartile: 3.470, Q1).

Linalool Bioactive Properties and Potential Applicability in Drug Delivery Systems.
Pereira, I.; Severino, Patrícia; Santos, Ana C.; Silva, Amélia M.; Souto, Eliana B. (2018) Linalool Bioactive Properties and Potential Applicability in Drug Delivery Systems. Colloids And Surfaces B-Biointerfaces 171 :566-578. doi: 10.1016/j.colsurfb.2018.08.001. (Impact factor, Quartile: 3.997, Q1).

Optimization of Linalool-loaded Solid Lipid Nanoparticles using Experimental Factorial Design and Long-term Stability Studies with a New Centrifugal Sedimentation Method.
Pereira, I.; Alexandra Zielińska; Nuno R. Ferreira; Amélia M. Silva; Eliana B. Souto (2018) Optimization of Linalool-loaded Solid Lipid Nanoparticles using Experimental Factorial Design and Long-term Stability Studies with a New Centrifugal Sedimentation Method. International Journal Of Pharmaceutics 549 (1) :261-270. doi: 10.1016/j.ijpharm.2018.07.068. (Impact factor, Quartile: 3.862, Q1).

Memantine-Loaded PEGylated Biodegradable Nanoparticles for the Treatment of Glaucoma.
Sanchez-Lopez, Elena; Antonia Egea, Maria; Davis, Benjamin Michael; Guo, Li; Espina, Marta; Silva, Amelia Maria; Cristina Calpena, Ana; Barbosa Souto, Eliana Maria; Ravindran, Nivedita; Ettcheto, Miren; Camins, Antonio; Luisa Garcia, Maria; Cordeiro, Maria Francesca (2018) Memantine-Loaded PEGylated Biodegradable Nanoparticles for the Treatment of Glaucoma. Small 14 (2). doi: 10.1002/smll.201701808. (Impact factor, Quartile: 9.598, Q1).

Memantine loaded PLGA PEGylated nanoparticles for Alzheimer's disease: in vitro and in vivo characterization.
Sanchez-Lopez, Elena; Ettcheto, Miren; Antonia Egea, Maria; Espina, Marta; Cano, Amanda; Cristina Calpena, Ana; Camins, Antoni; Carmona, Nuria; Silva, Amelia M.; Souto, Eliana B.; Luisa Garcia, Maria (2018) Memantine loaded PLGA PEGylated nanoparticles for Alzheimer's disease: in vitro and in vivo characterization. Journal Of Nanobiotechnology 16. doi: 10.1186/s12951-018-0356-z. (Impact factor, Quartile: 5.294, Q1).

Titanium dioxide nanoparticles: Toxicity and genotoxicity in Drosophila melanogaster (SMART eye-spot test and comet assay in neuroblasts).
Sario, Sara; Silva, Amelia M.; Gaivao, Isabel (2018) Titanium dioxide nanoparticles: Toxicity and genotoxicity in Drosophila melanogaster (SMART eye-spot test and comet assay in neuroblasts). Mutation Research-Genetic Toxicology And Environmental Mutagenesis 831 :19-23. doi: 10.1016/j.mrgentox.2018.05.001. (Impact factor, Quartile: 1.996, Q3).

Optimization, Biopharmaceutical Profile and Therapeutic Efficacy of Pioglitazone-loaded PLGA-PEG Nanospheres as a Novel Strategy for Ocular Inflammatory Disorders.
Silva-Abreu, Marcelle; Cristina Calpena, Ana; Espina, Marta; Silva, Amelia M.; Gimeno, Alvaro; Antonia Egea, Maria; Luisa Garcia, Maria (2018) Optimization, Biopharmaceutical Profile and Therapeutic Efficacy of Pioglitazone-loaded PLGA-PEG Nanospheres as a Novel Strategy for Ocular Inflammatory Disorders. Pharmaceutical Research 35 (1). doi: 10.1007/s11095-017-2319-8. (Impact factor, Quartile: 3.335, Q2).

Thymus pulegioides L. as a rich source of antioxidant, anti-proliferative and neuroprotective phenolic compounds.
Taghouti, Meriem; Martins-Gomes, Carlos; Schaefer, Judith; Felix, Luis M.; Santos, Joao A.; Bunzel, Mirko; Nunes, Fernando M.; Silva, Amelia M. (2018) Thymus pulegioides L. as a rich source of antioxidant, anti-proliferative and neuroprotective phenolic compounds. Food & Function 9 (7) :3617-3629. doi: 10.1039/c8fo00456k. (Impact factor, Quartile: 3.289, Q1).

Anti-inflammatory and Anti-cancer Activity of Citral: Optimization of Citral-loaded Solid Lipid Nanoparticles (SLN) using Experimental Factorial Design and LUMiSizer.
Zielińska, Alexandra; Martins-Gomes, Carlos; Ferreira, Nuno R. ; Silva, Amélia M.; Nowak, I.; Souto, Eliana B. (2018) Anti-inflammatory and Anti-cancer Activity of Citral: Optimization of Citral-loaded Solid Lipid Nanoparticles (SLN) using Experimental Factorial Design and LUMiSizer. INTERNATIONAL JOURNAL OF PHARMACEUTICS 553 (1-2) :428-440. doi: 10.1016/j.ijpharm.2018.10.065. (Impact factor, Quartile: 3.862, Q1).

Ibuprofen Nanocrystals Developed by 22 Factorial Design Experiment: a New Approach for Poorly Water-Soluble Drugs.
Fernandes, A.R.; Ferreira, N.R.; Fangueiro, J.F.; Santos, A.C.; Veiga, F.J.; Cabral, C.; Silva, A.M;, Souto, E.B. (2017) Ibuprofen Nanocrystals Developed by 22 Factorial Design Experiment: a New Approach for Poorly Water-Soluble Drugs. Saudi Pharmaceutical Journal 25 (8) :1117-1124. ISSN: 1319-0164. doi: 10.1016/j.jsps.2017.07.004. (Impact factor, Quartile: 3.110, Q2).

Projects

FungiTech - Technology and innovation in the production chain of shiitake and other mushrooms with nutraceutical value and medicine
Running

Coordinator  /  Guilhermina Marques
Start date  /  2018/07 Funding  /  Norte2020


Safe NPest: Synthesis and Environmental Safety of Nanopesticides
Running

Coordinator  /  Amélia Silva
Start date  /  2018/07 Funding  /  FCT/FEDER


PAIRED - Magnetically and photochemically actuated bioactive nanowires for remotely controlled drug delivery
Running

Coordinator  /  Amélia Silva
Start date  /  2016/10 Funding  /  European Commission - ERA-NETS


INTERACT - Integrative Research in Environment, Agro-Chains and Technology
Running

Coordinator  /  Rui Cortes
Start date  /  2016/05 Funding  /  NORTE2020


IBERPHENOL- Research cooperation network in polyphenols and its industrial applications”
Running

Coordinator  /  Eduardo Rosa
Start date  /  2015/10 Funding  /  INTERREG - POCTEP (Spain - Portugal)


INNOFOOD - INNOVation in the FOOD sector through the valorization of food and agro-food by-products
Concluded

Coordinator  /  Ana Barros
Start date  /  2014/01


MELHORA DAS PROPRIEDADES DE SAUDE DOS ALIMENTOS, COMPARTILHANDO O CONHECIMENTO SOBRE O PROCESSO DIGESTIVO (INFOGEST)
Concluded

Coordinator  /  Raul Perles
Start date  /  2013/05 Funding  /  European Cooperation in Science and Technology (COST)


NanoSKIN: Nanopartículas contendo agentes quimioterapêuticos para terapias inovadoras de doenças severas da pele – Leishmaniase muco/cutânea e carcinoma espinocelular como exemplos.
Concluded

Coordinator  /  Amélia Silva
Start date  /  2011/05


PromoAgro - Promoção da Competitividade Agro-alimentar
Concluded

Coordinator  /  Eduardo Rosa
Start date  /  2010/10 Funding  /  CCDRN - ON.2


NutriDouro: Frutas confitadas e compotas saudáveis, o sabor tradicional
Concluded

Start date  /  2010/06 Funding  /  QREN-Copromoção