Publications
From cultural and natural heritage to reservoir of biomedicine: Prospection of bioactive compounds produced by bacterial isolates from caves
Gatinho P., Salvador C., Gutierrez-Patricio S., Macedo-Arantes S., Martins M.R., Silva A.M., Miller A.Z., Caldeira A.T.,
(2024)
From cultural and natural heritage to reservoir of biomedicine: Prospection of bioactive compounds produced by bacterial isolates from caves
International Biodeterioration and Biodegradation
190
(105773).
doi: 10.1016/j.ibiod.2024.105773.
Hibiscus sabdariffa-loaded nanostructured lipid carriers (NLC) for fortified nutraceutical milks
Pimentel-Moral S., Durazzo A., Lucarini M., Fernández-Ochoa Á., de la Luz Cádiz-Gurrea M., Arráez-Román D., Silva A.M., Santini A., Fonseca J., Segura-Carretero A., Souto E.B.,
(2024)
Hibiscus sabdariffa-loaded nanostructured lipid carriers (NLC) for fortified nutraceutical milks
European Food Research and Technology
250
:1999-2010.
ISSN: 14382385.
doi: 10.1007/s00217-024-04509-9.
Labdanum Resin from Cistus ladanifer L. as a Source of Compounds with Anti-Diabetic, Neuroprotective and Anti-Proliferative Activity
Frazão D.F., Martins-Gomes C., Díaz T.S., Delgado F., Gonçalves J.C., Silva A.M.,
(2024)
Labdanum Resin from Cistus ladanifer L. as a Source of Compounds with Anti-Diabetic, Neuroprotective and Anti-Proliferative Activity
Molecules
29
(2222).
ISSN: 14203049.
doi: 10.3390/molecules29102222.
Linking Variability in Phytochemical Composition with Safety Profile of Thymus carnosus Boiss. Extracts: Effect of Major Compounds and Evaluation of Markers of Oxidative Stress and Cell Death
Martins-Gomes C., Nunes F.M., Silva A.M.,
(2024)
Linking Variability in Phytochemical Composition with Safety Profile of Thymus carnosus Boiss. Extracts: Effect of Major Compounds and Evaluation of Markers of Oxidative Stress and Cell Death
International Journal of Molecular Sciences
25
(5343).
ISSN: 14220067.
doi: 10.3390/ijms25105343.
Biopharmaceutical applications of Opuntia ficus-indica: bibliometric map, bioactivities and extraction techniques
Guedes B.N., Fathi F., Silva A.M., Santini A., Oliveira M.B.P.P., Souto E.B.,
(2023)
Biopharmaceutical applications of Opuntia ficus-indica: bibliometric map, bioactivities and extraction techniques
European Food Research and Technology
249
:2457-2469.
ISSN: 14382385.
doi: 10.1007/s00217-023-04314-w.
Cell penetrating peptides-functionalized Licochalcone-A-loaded PLGA nanoparticles for ocular inflammatory diseases: Evaluation of in vitro anti-proliferative effects, stabilization by freeze-drying and characterization of an in-situ forming gel
Galindo-Camacho R.M., Haro I., Gómara M.J., Espina M., Fonseca J., Martins-Gomes C., Camins A., Silva A.M., García M.L., Souto E.B.,
(2023)
Cell penetrating peptides-functionalized Licochalcone-A-loaded PLGA nanoparticles for ocular inflammatory diseases: Evaluation of in vitro anti-proliferative effects, stabilization by freeze-drying and characterization of an in-situ forming gel
International Journal of Pharmaceutics
639
(122982).
ISSN: 18733476.
doi: 10.1016/j.ijpharm.2023.122982.
Effect of cultivar, maturation stage, and year on sugar and phenolic composition of elderberries
Ferreira S.S., Silva P., Silva A.M., Nunes F.M.,
(2023)
Effect of cultivar, maturation stage, and year on sugar and phenolic composition of elderberries
Journal of the Science of Food and Agriculture
103
:2023-2036.
ISSN: 10970010.
doi: 10.1002/jsfa.12271.
Modified Drug Delivery Systems for Veterinary Use: Pharmaceutical Development and Applications
Souto E.B., Barbosa C.I., Baldim I., Campos J.R., Fernandes A.R., Mazzola P.G., Andreani T., Dias I.R., Durazzo A., Lucarini M., Atanasov A.G., Silva A.M., Santini A.,
(2023)
Modified Drug Delivery Systems for Veterinary Use: Pharmaceutical Development and Applications
Current Bioactive Compounds
19
(e040422203061)
:69-76.
ISSN: 18756646.
doi: 10.2174/1573407218666220404110837.
Modulation of Cell Death Pathways for Cellular Protection and Anti-Tumoral Activity: The Role of Thymus spp. Extracts and Their Bioactive Molecules
Martins-Gomes C., Nunes F.M., Silva A.M.,
(2023)
Modulation of Cell Death Pathways for Cellular Protection and Anti-Tumoral Activity: The Role of Thymus spp. Extracts and Their Bioactive Molecules
International Journal of Molecular Sciences
24
(1691).
ISSN: 14220067.
doi: 10.3390/ijms24021691.
Molecular Characterization of Prunus lusitanica L. Fruit Extracts and Their Health-Promoting Potential in Inflammation, Diabetes, and Neurodegenerative Diseases
Abraão A., Martins-Gomes C., Domínguez-Perles R., Barros A., Silva A.M.,
(2023)
Molecular Characterization of Prunus lusitanica L. Fruit Extracts and Their Health-Promoting Potential in Inflammation, Diabetes, and Neurodegenerative Diseases
International Journal of Molecular Sciences
24
(8830).
ISSN: 14220067.
doi: 10.3390/ijms24108830.
Natural Products as a Tool to Modulate the Activity and Expression of Multidrug Resistance Proteins of Intestinal Barrier
Martins-Gomes C., Silva A.M.,
(2023)
Natural Products as a Tool to Modulate the Activity and Expression of Multidrug Resistance Proteins of Intestinal Barrier
Journal of Xenobiotics
13
:172-192.
ISSN: 20394713.
doi: 10.3390/jox13020014.
Phytochemical Composition and Antioxidant, Anti-Acetylcholinesterase, and Anti-α-Glucosidase Activity of Thymus carnosus Extracts: A Three-Year Study on the Impact of Annual Variation and Geographic Location
Martins-Gomes C., Steck J., Keller J., Bunzel M., Santos J.A., Nunes F.M., Silva A.M.,
(2023)
Phytochemical Composition and Antioxidant, Anti-Acetylcholinesterase, and Anti-α-Glucosidase Activity of Thymus carnosus Extracts: A Three-Year Study on the Impact of Annual Variation and Geographic Location
Antioxidants
12
(668).
ISSN: 20763921.
doi: 10.3390/antiox12030668.
Prokaryotic Communities from Pristine Cave Environments: Biotechnological Potential with Sustainable Production
Gatinho P., Salvador C., Silva A.M., Caldeira A.T.,
(2023)
Prokaryotic Communities from Pristine Cave Environments: Biotechnological Potential with Sustainable Production
Sustainability (Switzerland)
15
(7471).
ISSN: 20711050.
doi: 10.3390/su15097471.
Prunus lusitanica L. Fruits: A Promising Underexploited Source of Nutrients with Potential Economic Value
Abraão A., Yu M., Gouvinhas I., Ferreira L., Silva A.M., Domínguez-Perles R., Barros A.,
(2023)
Prunus lusitanica L. Fruits: A Promising Underexploited Source of Nutrients with Potential Economic Value
Foods
12
(973).
ISSN: 23048158.
doi: 10.3390/foods12050973.
Rockrose Land Management: Contribution of Periodic Harvesting to Increase Value and to Control Cistus ladanifer L. Shrublands
Frazão D.F., Gonçalves J.C., Silva A.M., Delgado F.,
(2023)
Rockrose Land Management: Contribution of Periodic Harvesting to Increase Value and to Control Cistus ladanifer L. Shrublands
Forests
14
(638).
ISSN: 19994907.
doi: 10.3390/f14030638.
Applications of nanotechnology in chronic diseases and tissue regeneration
Formoso I., Shegokar R., Zielinska A., Silva A.M., Souto E.B.,
(2022)
Applications of nanotechnology in chronic diseases and tissue regeneration
Nanotechnology and Regenerative Medicine: History, Techniques, Frontiers, and Applications
:507-527.
doi: 10.1016/B978-0-323-90471-1.00021-9.
Chemical Composition and Potential Biological Activity of Melanoidins From Instant Soluble Coffee and Instant Soluble Barley: A Comparative Study
Antonietti S., Silva A.M., Simões C., Almeida D., Félix L.M., Papetti A., Nunes F.M.,
(2022)
Chemical Composition and Potential Biological Activity of Melanoidins From Instant Soluble Coffee and Instant Soluble Barley: A Comparative Study
Frontiers in Nutrition
9
(825584).
ISSN: 2296861X.
doi: 10.3389/fnut.2022.825584.
Customized cationic nanoemulsions loading triamcinolone acetonide for corneal neovascularization secondary to inflammatory processes
Fernandes A.R., Vidal L.B., Sánchez-López E., dos Santos T., Granja P.L., Silva A.M., Garcia M.L., Souto E.B.,
(2022)
Customized cationic nanoemulsions loading triamcinolone acetonide for corneal neovascularization secondary to inflammatory processes
International Journal of Pharmaceutics
623
(121938).
ISSN: 18733476.
doi: 10.1016/j.ijpharm.2022.121938.
Elderberry (Sambucus nigra L.) extracts promote anti-inflammatory and cellular antioxidant activity
Ferreira S.S., Martins-Gomes C., Nunes F.M., Silva A.M.,
(2022)
Elderberry (Sambucus nigra L.) extracts promote anti-inflammatory and cellular antioxidant activity
Food Chemistry: X
15
(100437).
ISSN: 25901575.
doi: 10.1016/j.fochx.2022.100437.
Exudative versus Nonexudative Age-Related Macular Degeneration: Physiopathology and Treatment Options
Fernandes A.R., Zielińska A., Sanchez-Lopez E., Dos Santos T., Garcia M.L., Silva A.M., Karczewski J., Souto E.B.,
(2022)
Exudative versus Nonexudative Age-Related Macular Degeneration: Physiopathology and Treatment Options
International Journal of Molecular Sciences
23
(2592).
ISSN: 14220067.
doi: 10.3390/ijms23052592.
Glyphosate vs. Glyphosate-Based Herbicides Exposure: A Review on Their Toxicity
Martins-Gomes C., Silva T.L., Andreani T., Silva A.M.,
(2022)
Glyphosate vs. Glyphosate-Based Herbicides Exposure: A Review on Their Toxicity
Journal of Xenobiotics
12
:21-40.
ISSN: 20394713.
doi: 10.3390/jox12010003.
Hydrogels for Modified-release Drug Delivery Systems
Zielińska A., Eder P., Rannier L., Cardoso J.C., Severino P., Silva A.M., Souto E.B.,
(2022)
Hydrogels for Modified-release Drug Delivery Systems
Current Pharmaceutical Design
28
:609-618.
ISSN: 18734286.
doi: 10.2174/1381612828666211230114755.
In Vitro Assessment of Pesticides Toxicity and Data Correlation with Pesticides Physicochemical Properties for Prediction of Toxicity in Gastrointestinal and Skin Contact Exposure
Silva A.M., Martins-Gomes C., Silva T.L., Coutinho T.E., Souto E.B., Andreani T.,
(2022)
In Vitro Assessment of Pesticides Toxicity and Data Correlation with Pesticides Physicochemical Properties for Prediction of Toxicity in Gastrointestinal and Skin Contact Exposure
Toxics
10
(378).
ISSN: 23056304.
doi: 10.3390/toxics10070378.
Labdanum Resin from Cistus ladanifer L.: A Natural and Sustainable Ingredient for Skin Care Cosmetics with Relevant Cosmeceutical Bioactivities
Frazão D.F., Martins-Gomes C., Steck J.L., Keller J., Delgado F., Gonçalves J.C., Bunzel M., Pintado C.M.B.S., Díaz T.S., Silva A.M.,
(2022)
Labdanum Resin from Cistus ladanifer L.: A Natural and Sustainable Ingredient for Skin Care Cosmetics with Relevant Cosmeceutical Bioactivities
Plants
11
(1477).
ISSN: 22237747.
doi: 10.3390/plants11111477.
Lipid nanoparticles-based semisolid formulations for cosmetic applications: focus on cellulite
Silva A.M., Cruz A.T., Nobre J., Coutinho T.E., Cano A., Zielinska A., Kovačević A., Severino P., Souto E.B.,
(2022)
Lipid nanoparticles-based semisolid formulations for cosmetic applications: focus on cellulite
Nanotechnology and Regenerative Medicine: History, Techniques, Frontiers, and Applications
:179-193.
doi: 10.1016/B978-0-323-90471-1.00014-1.
Lipid-Based Nanoparticulate Systems for the Ocular Delivery of Bioactives with Anti-Inflammatory Properties
Ana R.d., Fonseca J., Karczewski J., Silva A.M., Zielińska A., Souto E.B.,
(2022)
Lipid-Based Nanoparticulate Systems for the Ocular Delivery of Bioactives with Anti-Inflammatory Properties
International Journal of Molecular Sciences
23
(12102).
ISSN: 14220067.
doi: 10.3390/ijms232012102.
Lipid-Drug Conjugates and Nanoparticles for the Cutaneous Delivery of Cannabidiol
Zielińska A., Cano A., Andreani T., Martins-Gomes C., Silva A.M., Szalata M., Słomski R., Souto E.B.,
(2022)
Lipid-Drug Conjugates and Nanoparticles for the Cutaneous Delivery of Cannabidiol
International Journal of Molecular Sciences
23
(6165).
ISSN: 14220067.
doi: 10.3390/ijms23116165.
Major anthocyanins in elderberry effectively trap methylglyoxal and reduce cytotoxicity of methylglyoxal in HepG2 cell line
Ferreira S.S., Domingues M.R., Barros C., Santos S.A.O., Silvestre A.J.D., Silva A.M., Nunes F.M.,
(2022)
Major anthocyanins in elderberry effectively trap methylglyoxal and reduce cytotoxicity of methylglyoxal in HepG2 cell line
Food Chemistry: X
16
(100468).
ISSN: 25901575.
doi: 10.1016/j.fochx.2022.100468.
Microemulsions and Nanoemulsions in Skin Drug Delivery
Souto E.B., Cano A., Martins-Gomes C., Coutinho T.E., Zielińska A., Silva A.M.,
(2022)
Microemulsions and Nanoemulsions in Skin Drug Delivery
Bioengineering
9
(158).
ISSN: 23065354.
doi: 10.3390/bioengineering9040158.
Molecular Characterization of Thymus capitellatus Extracts and Their Antioxidant, Neuroprotective and Anti-Proliferative Activities
Martins-Gomes C., Steck J., Keller J., Bunzel M., Nunes F.M., Silva A.M.,
(2022)
Molecular Characterization of Thymus capitellatus Extracts and Their Antioxidant, Neuroprotective and Anti-Proliferative Activities
International Journal of Molecular Sciences
23
(15187).
ISSN: 14220067.
doi: 10.3390/ijms232315187.
Molecular Physicochemical Properties of Selected Pesticides as Predictive Factors for Oxidative Stress and Apoptosis-Dependent Cell Death in Caco-2 and HepG2 Cells
Silva A.M., Martins-Gomes C., Ferreira S.S., Souto E.B., Andreani T.,
(2022)
Molecular Physicochemical Properties of Selected Pesticides as Predictive Factors for Oxidative Stress and Apoptosis-Dependent Cell Death in Caco-2 and HepG2 Cells
International Journal of Molecular Sciences
23
(8107).
ISSN: 14220067.
doi: 10.3390/ijms23158107.
Nanophytosomes: a novel approach for the delivery of herbal drugs
Martins-Gomes C., Souto E.B., Silva A.M.,
(2022)
Nanophytosomes: a novel approach for the delivery of herbal drugs
Systems of Nanovesicular Drug Delivery
:239-257.
doi: 10.1016/B978-0-323-91864-0.00015-2.
Nanotechnologies to deliver drugs through the blood–brain and blood–retinal barriers
Costa M.C., Shegokar R., Silva A.M., Souto E.B.,
(2022)
Nanotechnologies to deliver drugs through the blood–brain and blood–retinal barriers
Nanotechnology and Regenerative Medicine: History, Techniques, Frontiers, and Applications
:45-64.
doi: 10.1016/B978-0-323-90471-1.00010-4.
Neurotoxicity Assessment of Four Different Pesticides Using In Vitro Enzymatic Inhibition Assays
Martins-Gomes C., Coutinho T.E., Silva T.L., Andreani T., Silva A.M.,
(2022)
Neurotoxicity Assessment of Four Different Pesticides Using In Vitro Enzymatic Inhibition Assays
Toxics
10
(448).
ISSN: 23056304.
doi: 10.3390/toxics10080448.
Permeability, anti-inflammatory and anti-VEGF profiles of steroidal-loaded cationic nanoemulsions in retinal pigment epithelial cells under oxidative stress
Fernandes A.R., dos Santos T., Granja P.L., Sanchez-Lopez E., Garcia M.L., Silva A.M., Souto E.B.,
(2022)
Permeability, anti-inflammatory and anti-VEGF profiles of steroidal-loaded cationic nanoemulsions in retinal pigment epithelial cells under oxidative stress
International Journal of Pharmaceutics
617
(121615).
ISSN: 18733476.
doi: 10.1016/j.ijpharm.2022.121615.
Physicochemical and biopharmaceutical aspects influencing skin permeation and role of SLN and NLC for skin drug delivery
Souto E.B., Fangueiro J.F., Fernandes A.R., Cano A., Sanchez-Lopez E., Garcia M.L., Severino P., Paganelli M.O., Chaud M.V., Silva A.M.,
(2022)
Physicochemical and biopharmaceutical aspects influencing skin permeation and role of SLN and NLC for skin drug delivery
Heliyon
8
(e08938).
doi: 10.1016/j.heliyon.2022.e08938.
Production Technologies, Regulatory Parameters, and Quality Control of Vaccine Vectors for Veterinary Use
Barbosa R.d.M., Silva A.M., Silva C.F.d., Cardoso J.C., Severino P., Meirelles L.M.A., Silva-Junior A.A.d., Viseras C., Fonseca J., Souto E.B.,
(2022)
Production Technologies, Regulatory Parameters, and Quality Control of Vaccine Vectors for Veterinary Use
Technologies
10
(109).
ISSN: 22277080.
doi: 10.3390/technologies10050109.
Progress of nanotechnology in the development of medicines
Formoso I., Shegokar R., Zielinska A., Eder P., Silva A.M., Souto E.B.,
(2022)
Progress of nanotechnology in the development of medicines
Nanotechnology and Regenerative Medicine: History, Techniques, Frontiers, and Applications
:1-21.
doi: 10.1016/B978-0-323-90471-1.00001-3.
Prunus lusitanica L. Fruits as a Novel Source of Bioactive Compounds with Antioxidant Potential: Exploring the Unknown
Abraão A.S., Fernandes N., Silva A.M., Domínguez-Perles R., Barros A.,
(2022)
Prunus lusitanica L. Fruits as a Novel Source of Bioactive Compounds with Antioxidant Potential: Exploring the Unknown
Antioxidants
11
(1738).
ISSN: 20763921.
doi: 10.3390/antiox11091738.
Selected Flavonoids to Target Melanoma: A Perspective in Nanoengineering Delivery Systems
Coutinho T.E., Souto E.B., Silva A.M.,
(2022)
Selected Flavonoids to Target Melanoma: A Perspective in Nanoengineering Delivery Systems
Bioengineering
9
(290).
ISSN: 23065354.
doi: 10.3390/bioengineering9070290.
Toxicological screening of nanoparticles for biological applications: Drosophila melanogaster as a representative toxicological model
Severino P., Dias-Ferreira J., Andrade L.N., Lima D.M., de Hollanda L.M., da Silva C.F., Chaud M.V., Carbone C., Silva A.M., Lucarini M., Durazzo A., Capasso R., Santini A., Souto E.B.,
(2022)
Toxicological screening of nanoparticles for biological applications: Drosophila melanogaster as a representative toxicological model
Nanotechnology and Regenerative Medicine: History, Techniques, Frontiers, and Applications
:551-573.
doi: 10.1016/B978-0-323-90471-1.00007-4.
Uncaria tomentosa (Willd. ex Schult.): Focus on Nutraceutical Aspects
Nazhand A., Durazzo A., Lucarini M., Silva A.M., Souto S.B., Severino P., Souto E.B., Santini A.,
(2022)
Uncaria tomentosa (Willd. ex Schult.): Focus on Nutraceutical Aspects
Current Bioactive Compounds
18
(e021221196131).
ISSN: 18756646.
doi: 10.2174/1573407217666210903113347.
Astragalus (Astragalus membranaceus Bunge): botanical, geographical, and historical aspects to pharmaceutical components and beneficial role
Durazzo A., Nazhand A., Lucarini M., Silva A.M., Souto S.B., Guerra F., Severino P., Zaccardelli M., Souto E.B., Santini A.,
(2021)
Astragalus (Astragalus membranaceus Bunge): botanical, geographical, and historical aspects to pharmaceutical components and beneficial role
Rendiconti Lincei
32
:625-642.
ISSN: 17200776.
doi: 10.1007/s12210-021-01003-2.
Biosurfactants: Properties and applications in drug delivery, biotechnology and ecotoxicology
Bjerk T.R., Severino P., Jain S., Marques C., Silva A.M., Pashirova T., Souto E.B.,
(2021)
Biosurfactants: Properties and applications in drug delivery, biotechnology and ecotoxicology
Bioengineering
8
(115).
ISSN: 23065354.
doi: 10.3390/bioengineering8080115.
Dabco-customized nanoemulsions: Characterization, cell viability and genotoxicity in retinal pigmented epithelium and microglia cells
Fernandes A.R., Dos Santos T., Granja P.L., Sanchez-Lopez E., Santini A., Garcia M.L., Silva A.M., Souto E.B.,
(2021)
Dabco-customized nanoemulsions: Characterization, cell viability and genotoxicity in retinal pigmented epithelium and microglia cells
Pharmaceutics
13
(1652).
ISSN: 19994923.
doi: 10.3390/pharmaceutics13101652.
Development and characterization of nanoemulsions for ophthalmic applications: Role of cationic surfactants
Fernandes A.R., Sanchez-Lopez E., Dos Santos T., Garcia M.L., Silva A.M., Souto E.B.,
(2021)
Development and characterization of nanoemulsions for ophthalmic applications: Role of cationic surfactants
Materials
14
(7541).
ISSN: 19961944.
doi: 10.3390/ma14247541.
Ecotoxicity to freshwater organisms and cytotoxicity of nanomaterials: Are we generating sufficient data for their risk assessment?
Andreani T., Nogueira V., Gavina A., Fernandes S., Rodrigues J.L., Pinto V.V., Ferreira M.J., Silva A.M., Pereira C.M., Pereira R.,
(2021)
Ecotoxicity to freshwater organisms and cytotoxicity of nanomaterials: Are we generating sufficient data for their risk assessment?
Nanomaterials
11
(66)
:1-25.
ISSN: 20794991.
doi: 10.3390/nano11010066.
Genotoxicity assessment of metal-based nanocomposites applied in drug delivery
Cardoso S., da Silva C.F., Severino P., Silva A.M., Souto S.B., Zielińska A., Karczewski J., Souto E.B.,
(2021)
Genotoxicity assessment of metal-based nanocomposites applied in drug delivery
Materials
14
(6551).
ISSN: 19961944.
doi: 10.3390/ma14216551.
Mono-and dicationic dabco/quinuclidine composed nanomaterials for the loading of steroidal drug: 32 factorial design and physicochemical characterization
Fernandes A.R., Sanchez-Lopez E., Santini A., Dos Santos T., Garcia M.L., Silva A.M., Souto E.B.,
(2021)
Mono-and dicationic dabco/quinuclidine composed nanomaterials for the loading of steroidal drug: 32 factorial design and physicochemical characterization
Nanomaterials
11
(2758).
ISSN: 20794991.
doi: 10.3390/nano11102758.
Orange thyme: Phytochemical profiling, in vitro bioactivities of extracts and potential health benefits
Silva A.M., Félix L.M., Teixeira I., Martins-Gomes C., Schäfer J., Souto E.B., Santos D.J., Bunzel M., Nunes F.M.,
(2021)
Orange thyme: Phytochemical profiling, in vitro bioactivities of extracts and potential health benefits
Food Chemistry: X
12
(100171).
ISSN: 25901575.
doi: 10.1016/j.fochx.2021.100171.
Red seaweeds strengthening the nexus between nutrition and health: phytochemical characterization and bioactive properties of Grateloupia turuturu and Porphyra umbilicalis extracts
Ferreira J., Hartmann A., Martins-Gomes C., Nunes F.M., Souto E.B., Santos D.L., Abreu H., Pereira R., Pacheco M., Gaivão I., Silva A.M.,
(2021)
Red seaweeds strengthening the nexus between nutrition and health: phytochemical characterization and bioactive properties of Grateloupia turuturu and Porphyra umbilicalis extracts
Journal of Applied Phycology
33
:3365-3381.
ISSN: 15735176.
doi: 10.1007/s10811-021-02529-6.
(+)-limonene 1,2-epoxide-loaded slns: Evaluation of drug release, antioxidant activity, and cytotoxicity in an HaCaT cell line
Souto E.B., Zielinska A., Souto S.B., Durazzo A., Lucarini M., Santini A., Silva A.M., Atanasov A.G., Marques C., Andrade L.N., Severino P.,
(2020)
(+)-limonene 1,2-epoxide-loaded slns: Evaluation of drug release, antioxidant activity, and cytotoxicity in an HaCaT cell line
International Journal of Molecular Sciences
21
(1449).
ISSN: 14220067.
doi: 10.3390/ijms21041449.
Chemical characterization and bioactivity of extracts from Thymus mastichina: A thymus with a distinct salvianolic acid composition
Taghouti M., Martins-Gomes C., Schäfer J., Santos J.A., Bunzel M., Nunes F.M., Silva A.M.,
(2020)
Chemical characterization and bioactivity of extracts from Thymus mastichina: A thymus with a distinct salvianolic acid composition
Antioxidants
9
(34).
ISSN: 20763921.
doi: 10.3390/antiox9010034.
Diabetic retinopathy and ocular melanoma: How far we are?
Souto E.B., Campos J.R., Da Ana R., Fangueiro J.F., Martins-Gomes C., Durazzo A., Lucarini M., López E.S., Espina M., García M.L., Silva A.M., Mendonça F., Santini A., Souto S.B.,
(2020)
Diabetic retinopathy and ocular melanoma: How far we are?
Applied Sciences (Switzerland)
10
(2777).
ISSN: 20763417.
doi: 10.3390/APP10082777.
Effect of harvesting year and elderberry cultivar on the chemical composition and potential bioactivity: A three-year study
Ferreira S.S., Silva P., Silva A.M., Nunes F.M.,
(2020)
Effect of harvesting year and elderberry cultivar on the chemical composition and potential bioactivity: A three-year study
Food Chemistry
302
(125366).
ISSN: 18737072.
doi: 10.1016/j.foodchem.2019.125366.
Formulating octyl methoxycinnamate in hybrid lipid-silica nanoparticles: An innovative approach for UV skin protection
Andreani T., Dias-Ferreira J., Fangueiro J.F., Souza A.L.R., Kiill C.P., Gremião M.P.D., García M.L., Silva A.M., Souto E.B.,
(2020)
Formulating octyl methoxycinnamate in hybrid lipid-silica nanoparticles: An innovative approach for UV skin protection
Heliyon
6
(e03831).
doi: 10.1016/j.heliyon.2020.e03831.
Hawthorn (Crataegus spp.): An updated overview on its beneficial properties
Nazhand A., Lucarini M., Durazzo A., Zaccardelli M., Cristarella S., Souto S.B., Silva A.M., Severino P., Souto E.B., Santini A.,
(2020)
Hawthorn (Crataegus spp.): An updated overview on its beneficial properties
Forests
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In vitro characterization, modelling, and antioxidant properties of polyphenon-60 from green tea in eudragit s100-2 chitosan microspheres
Souto E.B., da Ana R., Souto S.B., Zielińska A., Marques C., Andrade L.N., Horbańczuk O.K., Atanasov A.G., Lucarini M., Durazzo A., Silva A.M., Novellino E., Santini A., Severino P.,
(2020)
In vitro characterization, modelling, and antioxidant properties of polyphenon-60 from green tea in eudragit s100-2 chitosan microspheres
Nutrients
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In vitro phototherapeutic effects of indolenine-based mono- and dithiosquaraine cyanine dyes against Caco-2 and HepG2 human cancer cell lines
Fernandes T.C.D., Lima E., Boto R.E., Ferreira D., Fernandes J.R., Almeida P., Ferreira L.F.V., Silva A.M., Reis L.V.,
(2020)
In vitro phototherapeutic effects of indolenine-based mono- and dithiosquaraine cyanine dyes against Caco-2 and HepG2 human cancer cell lines
Photodiagnosis and Photodynamic Therapy
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Lipid nanoparticles as carriers for the treatment of neurodegeneration associated with alzheimer’s disease and glaucoma: Present and future challenges
Lopez E.S., Machado A.L.L., Vidal L.B., Gonzalez-Pizarro R., Silva A.D., Souto E.B.,
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Lipid nanoparticles as carriers for the treatment of neurodegeneration associated with alzheimer’s disease and glaucoma: Present and future challenges
Current Pharmaceutical Design
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Metal-based nanoparticles as antimicrobial agents: An overview
Sánchez-López E., Gomes D., Esteruelas G., Bonilla L., Lopez-Machado A.L., Galindo R., Cano A., Espina M., Ettcheto M., Camins A., Silva A.M., Durazzo A., Santini A., Garcia M.L., Souto E.B.,
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Metal-based nanoparticles as antimicrobial agents: An overview
Nanomaterials
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Multiple cell signalling pathways of human proinsulin C-peptide in vasculopathy protection
Souto S.B., Campos J.R., Fangueiro J.F., Silva A.M., Cicero N., Santini A., Souto E.B.,
(2020)
Multiple cell signalling pathways of human proinsulin C-peptide in vasculopathy protection
International Journal of Molecular Sciences
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Nanomaterials for skin delivery of cosmeceuticals and pharmaceuticals
Souto E.B., Fernandes A.R., Martins-Gomes C., Coutinho T.E., Durazzo A., Lucarini M., Souto S.B., Silva A.M., Santini A.,
(2020)
Nanomaterials for skin delivery of cosmeceuticals and pharmaceuticals
Applied Sciences (Switzerland)
10
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ISSN: 20763417.
doi: 10.3390/app10051594.
Ocular cell lines and genotoxicity assessment
Souto E.B., Campos J.R., Da Ana R., Martins-Gomes C., Silva A.M., Souto S.B., Lucarini M., Durazzo A., Santini A.,
(2020)
Ocular cell lines and genotoxicity assessment
International Journal of Environmental Research and Public Health
17
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Parental metabolic syndrome epigenetically reprograms offspring hepatic lipid metabolism in mice
de Jesus D.F., Orime K., Kaminska D., Kimura T., Basile G., Wang C.H., Haertle L., Riemens R., Brown N.K., Hu J., Männistö V., Silva A.M., Dirice E., Tseng Y.H., Haaf T., Pihlajamäki J., Kulkarni R.N.,
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Parental metabolic syndrome epigenetically reprograms offspring hepatic lipid metabolism in mice
Journal of Clinical Investigation
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Perillaldehyde 1,2-epoxide loaded SLN-tailored mAb: Production, physicochemical characterization and in vitro cytotoxicity profile in MCF-7 cell lines
Souto E.B., Souto S.B., Zielinska A., Durazzo A., Lucarini M., Santini A., Horbańczuk O.K., Atanasov A.G., Marques C., Andrade L.N., Silva A.M., Severino P.,
(2020)
Perillaldehyde 1,2-epoxide loaded SLN-tailored mAb: Production, physicochemical characterization and in vitro cytotoxicity profile in MCF-7 cell lines
Pharmaceutics
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Polymeric Nanoparticles: Production, Characterization, Toxicology and Ecotoxicology
Zielinska A., Carreiró F., Oliveira A.M., Neves A., Pires B., Nagasamy Venkatesh D., Durazzo A., Lucarini M., Eder P., Silva A.M., Santini A., Souto E.B.,
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Polymeric Nanoparticles: Production, Characterization, Toxicology and Ecotoxicology
Molecules
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Polyphenol composition and biological activity of Thymus citriodorus and Thymus vulgaris: Comparison with endemic Iberian Thymus species
Taghouti M., Martins-Gomes C., Félix L.M., Schäfer J., Santos J.A., Bunzel M., Nunes F.M., Silva A.M.,
(2020)
Polyphenol composition and biological activity of Thymus citriodorus and Thymus vulgaris: Comparison with endemic Iberian Thymus species
Food Chemistry
331
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Potential application of grape (Vitis vinifera L.) stem extracts in the cosmetic and pharmaceutical industries: Valorization of a by-product
Leal C., Gouvinhas I., Santos R.A., Rosa E., Silva A.M., Saavedra M.J., Barros A.I.R.N.A.,
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Potential application of grape (Vitis vinifera L.) stem extracts in the cosmetic and pharmaceutical industries: Valorization of a by-product
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Quinoline-and benzoselenazole-derived unsymmetrical squaraine cyanine dyes: Design, synthesis, photophysicochemical features and light-triggerable antiproliferative effects against breast cancer cell lines
Lima E., Boto R.E., Ferreira D., Fernandes J.R., Almeida P., Ferreira L.F.V., Souto E.B., Silva A.M., Reis L.V.,
(2020)
Quinoline-and benzoselenazole-derived unsymmetrical squaraine cyanine dyes: Design, synthesis, photophysicochemical features and light-triggerable antiproliferative effects against breast cancer cell lines
Materials
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Red and near-infrared absorbing dicyanomethylene squaraine cyanine dyes: Photophysicochemical properties and anti-tumor photosensitizing effects
Martins T.D., Lima E., Boto R.E., Ferreira D., Fernandes J.R., Almeida P., Ferreira L.F.V., Silva A.M., Reis L.V.,
(2020)
Red and near-infrared absorbing dicyanomethylene squaraine cyanine dyes: Photophysicochemical properties and anti-tumor photosensitizing effects
Materials
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Sage species case study on a spontaneous mediterranean plant to control phytopathogenic fungi and bacteria
Zaccardelli M., Pane C., Caputo M., Durazzo A., Lucarini M., Silva A.M., Severino P., Souto E.B., Santini A., De Feo V.,
(2020)
Sage species case study on a spontaneous mediterranean plant to control phytopathogenic fungi and bacteria
Forests
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Sucupira oil-loaded nanostructured lipid carriers (NLC): Lipid screening, factorial design, release profile, and cytotoxicity
Vieira R., Severino P., Nalone L.A., Souto S.B., Silva A.M., Lucarini M., Durazzo A., Santini A., Souto E.B.,
(2020)
Sucupira oil-loaded nanostructured lipid carriers (NLC): Lipid screening, factorial design, release profile, and cytotoxicity
Molecules
25
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The nutraceutical value of carnitine and its use in dietary supplements
Durazzo A., Lucarini M., Nazhand A., Souto S.B., Silva A.M., Severino P., Souto E.B., Santini A.,
(2020)
The nutraceutical value of carnitine and its use in dietary supplements
Molecules
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Thymus zygis subsp. zygis an endemic portuguese plant: Phytochemical profiling, antioxidant, anti-proliferative and anti-inflammatory activities
Silva A.M., Martins-Gomes C., Souto E.B., Schäfer J., Santos J.A., Bunzel M., Nunes F.M.,
(2020)
Thymus zygis subsp. zygis an endemic portuguese plant: Phytochemical profiling, antioxidant, anti-proliferative and anti-inflammatory activities
Antioxidants
9
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Two-and three-dimensional spectrofluorimetric qualitative analysis of selected vegetable oils for biomedical applications
Zielińska A., Kubasiewicz K., Wójcicki K., Silva A.M., Nunes F.M., Szalata M., Słomski R., Eder P., Souto E.B.,
(2020)
Two-and three-dimensional spectrofluorimetric qualitative analysis of selected vegetable oils for biomedical applications
Molecules
25
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Vitex agnus-castus l.: Main features and nutraceutical perspectives
Souto E.B., Durazzo A., Nazhand A., Lucarini M., Zaccardelli M., Souto S.B., Silva A.M., Severino P., Novellino E., Santini A.,
(2020)
Vitex agnus-castus l.: Main features and nutraceutical perspectives
Forests
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3D printing in the design of pharmaceutical dosage forms
Souto E.B., Campos J.C., Filho S.C., Teixeira M.C., Martins-Gomes C., Zielinska A., Carbone C., Silva A.M.,
(2019)
3D printing in the design of pharmaceutical dosage forms
Pharmaceutical Development and Technology
24
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Cationic surfactants: Self-assembly, structure-activity correlation and their biological applications
Zakharova L.Y., Pashirova T.N., Doktorovova S., Fernandes A.R., Sanchez-Lopez E., Silva A.M., Souto S.B., Souto E.B.,
(2019)
Cationic surfactants: Self-assembly, structure-activity correlation and their biological applications
International Journal of Molecular Sciences
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Clotrimazole-loaded mediterranean essential oils NLC: A synergic treatment of Candida skin infections
Carbone C., Teixeira M.D.C., Sousa M.D.C., Martins-Gomes C., Silva A.M., Souto E.M.B., Musumeci T.,
(2019)
Clotrimazole-loaded mediterranean essential oils NLC: A synergic treatment of Candida skin infections
Pharmaceutics
11
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Comparison of antiproliferative effect of epigallocatechin gallate when loaded into cationic solid lipid nanoparticles against different cell lines
Silva A.M., Martins-Gomes C., Fangueiro J.F., Andreani T., Souto E.B.,
(2019)
Comparison of antiproliferative effect of epigallocatechin gallate when loaded into cationic solid lipid nanoparticles against different cell lines
Pharmaceutical Development and Technology
24
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Development and optimization of alpha-pinene-loaded solid lipid nanoparticles (SLN) using experimental factorial design and dispersion analysis
Zielinska A., Ferreira N.R., Durazzo A., Lucarini M., Cicero N., El Mamouni S., Silva A.M., Nowak I., Santini A., Souto E.B.,
(2019)
Development and optimization of alpha-pinene-loaded solid lipid nanoparticles (SLN) using experimental factorial design and dispersion analysis
Molecules
24
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Ginkgo biloba L. Leaf extract protects HepG2 cells against paraquat-induced oxidative DNA damage
Silva A.M., Silva S.C., Soares J.P., Martins-Gomes C., Teixeira J.P., Leal F., Gaivão I.,
(2019)
Ginkgo biloba L. Leaf extract protects HepG2 cells against paraquat-induced oxidative DNA damage
Plants
8
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ISSN: 22237747.
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In vitro cytotoxicity of oleanolic/ursolic acids-loaded in PLGA nanoparticles in different cell lines
Silva A.M., Alvarado H.L., Abrego G., Martins-Gomes C., Garduño-Ramirez M.L., García M.L., Calpena A.C., Souto E.B.,
(2019)
In vitro cytotoxicity of oleanolic/ursolic acids-loaded in PLGA nanoparticles in different cell lines
Pharmaceutics
11
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Key production parameters for the development of solid lipid nanoparticles by high shear homogenization
Souto E., Doktorovova S., Zielinska A., Silva A.,
(2019)
Key production parameters for the development of solid lipid nanoparticles by high shear homogenization
Pharmaceutical Development and Technology
24
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Meglumine-based supra-amphiphile self-assembled in water as a skin drug delivery system: Influence of unfrozen bound water in the system bioadhesiveness
de Souza A.L.R., Fonseca M., Ferreira L.M.B., Kurokawa S.S.S., Kiill C.P., Ferreira N.N., dos Santos Pyrrho A., Sarmento V.H.V., Silva A.M., Gremião M.P.D., Ribeiro C.A.,
(2019)
Meglumine-based supra-amphiphile self-assembled in water as a skin drug delivery system: Influence of unfrozen bound water in the system bioadhesiveness
Colloids and Surfaces B: Biointerfaces
184
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doi: 10.1016/j.colsurfb.2019.110523.
Microemulsions: Principles, Scope, Methods, and Applications in Transdermal Drug Delivery.
Pereira, Irina; Antunes, Sara; Santos,Ana C.; Veiga, Francisco J.; Silva, Amélia M.; Boonme, Prapaporn; Souto, Eliana B.
(2019)
Microemulsions: Principles, Scope, Methods, and Applications in Transdermal Drug Delivery.
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:91-118.
ISBN: 9781771887649.
Myasthenia gravis: State of the art and new therapeutic strategies
Souto E.B., Lima B., Campos J.R., Martins-Gomes C., Souto S.B., Silva A.M.,
(2019)
Myasthenia gravis: State of the art and new therapeutic strategies
Journal of Neuroimmunology
337
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doi: 10.1016/j.jneuroim.2019.577080.
Nanoparticle delivery systems in the treatment of diabetes complications
Souto E.B., Souto S.B., Campos J.R., Severino P., Pashirova T.N., Zakharova L.Y., Silva A.M., Durazzo A., Lucarini M., Izzo A.A., Santini A.,
(2019)
Nanoparticle delivery systems in the treatment of diabetes complications
Molecules
24
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doi: 10.3390/molecules24234209.
Optimization of nimesulide-loaded solid lipid nanoparticles (SLN) by factorial design, release profile and cytotoxicity in human Colon adenocarcinoma cell line
Campos J.R., Fernandes A.R., Sousa R., Fangueiro J.F., Boonme P., Garcia M.L., Silva A.M., Naveros B.C., Souto E.B.,
(2019)
Optimization of nimesulide-loaded solid lipid nanoparticles (SLN) by factorial design, release profile and cytotoxicity in human Colon adenocarcinoma cell line
Pharmaceutical Development and Technology
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Photophysicochemical properties and in vitro phototherapeutic effects of iodoquinoline- and benzothiazole-derived unsymmetrical squaraine cyanine dyes
Friães S., Lima E., Boto R.E., Ferreira D., Fernandes J.R., Ferreira L.F.V., Silva A.M., Reis L.V.,
(2019)
Photophysicochemical properties and in vitro phototherapeutic effects of iodoquinoline- and benzothiazole-derived unsymmetrical squaraine cyanine dyes
Applied Sciences (Switzerland)
9
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ISSN: 20763417.
doi: 10.3390/app9245414.
Polyphenols for skin cancer: Chemical properties, structure-related mechanisms of action and new delivery systems
Souto E., Sampaio A., Campos J., Martins-Gomes C., Aires A., Silva A.,
(2019)
Polyphenols for skin cancer: Chemical properties, structure-related mechanisms of action and new delivery systems
Studies in Natural Products Chemistry
63
:21-42.
ISBN: 9780128179017.
doi: 10.1016/B978-0-12-817901-7.00002-2.
Rosmarinic Acid: Sources, Bioactivities and Health Benefits.
Martins-Gomes, Carlos; Nunes, Fernando M.; Sampaio, Ana C.; Souto, Eliana B.; Silva, Amélia M.
(2019)
Rosmarinic Acid: Sources, Bioactivities and Health Benefits.
IN: Ryan, Iman (Ed.) Phytochemicals: Plant Sources and Potential Health Benefits. Book Series: Plant Science Research and Practices. NovaScience Publishers, New York, USA
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ISBN: 978-1-53615-478-8.
Soft cationic nanoparticles for drug delivery: Production and cytotoxicity of solid lipid nanoparticles (SLNs)
Silva A.M., Martins-Gomes C., Coutinho T.E., Fangueiro J.F., Sanchez-Lopez E., Pashirova T.N., Andreani T., Souto E.B.,
(2019)
Soft cationic nanoparticles for drug delivery: Production and cytotoxicity of solid lipid nanoparticles (SLNs)
Applied Sciences (Switzerland)
9
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ISSN: 20763417.
doi: 10.3390/app9204438.
Sugar-lowering drugs for type 2 diabetes mellitus and metabolic syndrome—review of classical and new compounds: Part-i
Vieira R., Souto S.B., Sánchez-López E., Machado A.L., Severino P., Jose S., Santini A., Fortuna A., García M.L., Silva A.M., Souto E.B.,
(2019)
Sugar-lowering drugs for type 2 diabetes mellitus and metabolic syndrome—review of classical and new compounds: Part-i
Pharmaceuticals
12
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ISSN: 14248247.
doi: 10.3390/ph12040152.
Surface-tailored anti-HER2/neu-solid lipid nanoparticles for site-specific targeting MCF-7 and BT-474 breast cancer cells
Souto E.B., Doktorovova S., Campos J.R., Martins-Lopes P., Silva A.M.,
(2019)
Surface-tailored anti-HER2/neu-solid lipid nanoparticles for site-specific targeting MCF-7 and BT-474 breast cancer cells
European Journal of Pharmaceutical Sciences
128
:27-35.
ISSN: 18790720.
doi: 10.1016/j.ejps.2018.11.022.
The influence of polysaccharide coating on the physicochemical parameters and cytotoxicity of silica nanoparticles for hydrophilic biomolecules delivery
Andreani T., Fangueiro J., Severino P., de Souza A., Martins-Gomes C., Fernandes P., Calpena A., Gremião M., Souto E., Silva A.,
(2019)
The influence of polysaccharide coating on the physicochemical parameters and cytotoxicity of silica nanoparticles for hydrophilic biomolecules delivery
Nanomaterials
9
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ISSN: 20794991.
doi: 10.3390/nano9081081.
Therapeutic interventions for countering leishmaniasis and chagas’s disease: From traditional sources to nanotechnological systems
Souto E.B., Dias-Ferreira J., Craveiro S.A., Severino P., Sanchez-Lopez E., Garcia M.L., Silva A.M., Souto S.B., Mahant S.,
(2019)
Therapeutic interventions for countering leishmaniasis and chagas’s disease: From traditional sources to nanotechnological systems
Pathogens
8
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ISSN: 20760817.
doi: 10.3390/pathogens8030119.
Thymus carnosus extracts induce anti-proliferative activity in Caco-2 cells through mechanisms that involve cell cycle arrest and apoptosis
Martins-Gomes C., Souto E.B., Cosme F., Nunes F.M., Silva A.M.,
(2019)
Thymus carnosus extracts induce anti-proliferative activity in Caco-2 cells through mechanisms that involve cell cycle arrest and apoptosis
Journal of Functional Foods
54
:128-135.
doi: 10.1016/j.jff.2019.01.010.
Trends in atopic dermatitis—from standard pharmacotherapy to novel drug delivery systems
Souto E.B., Dias-Ferreira J., Oliveira J., Sanchez-Lopez E., Lopez-Machado A., Espina M., Garcia M.L., Souto S.B., Martins-Gomes C., Silva A.M.,
(2019)
Trends in atopic dermatitis—from standard pharmacotherapy to novel drug delivery systems
International Journal of Molecular Sciences
20
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ISSN: 14220067.
doi: 10.3390/ijms20225659.
Uveal melanoma: physiopathology and new in situ-specific therapies
Souto E.B., Zielinska A., Luis M., Carbone C., Martins-Gomes C., Souto S.B., Silva A.M.,
(2019)
Uveal melanoma: physiopathology and new in situ-specific therapies
Cancer Chemotherapy and Pharmacology
84
:15-32.
ISSN: 14320843.
doi: 10.1007/s00280-019-03860-z.
Anti-inflammatory and Anti-cancer Activity of Citral: Optimization of Citral-loaded Solid Lipid Nanoparticles (SLN) using Experimental Factorial Design and LUMiSizer.
Zielińska, Alexandra; Martins-Gomes, Carlos; Ferreira, Nuno R. ; Silva, Amélia M.; Nowak, I.; Souto, Eliana B.
(2018)
Anti-inflammatory and Anti-cancer Activity of Citral: Optimization of Citral-loaded Solid Lipid Nanoparticles (SLN) using Experimental Factorial Design and LUMiSizer.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
553
(2-Jan)
:428-440.
doi: 10.1016/j.ijpharm.2018.10.065.
(Impact factor, Quartile: 3.862, Q1).
Chemical characterization and bioactive properties of decoctions and hydroethanolic extracts of Thymus carnosus Boiss.
Martins-Gomes, Carlos; Taghouti, Meriem; Schaefer, Judith; Bunzel, Mirko; Silva, Amelia M.; Nunes, Fernando M.
(2018)
Chemical characterization and bioactive properties of decoctions and hydroethanolic extracts of Thymus carnosus Boiss.
Journal Of Functional Foods
43
:154-164.
doi: 10.1016/j.jff.2018.02.012.
(Impact factor, Quartile: 3.47, Q1).
Citrus reticulata Blanco peels as a source of antioxidant and anti-proliferative phenolic compounds.
Ferreira, Sandrine S.; Silva, Amelia M.; Nunes, Fernando M.
(2018)
Citrus reticulata Blanco peels as a source of antioxidant and anti-proliferative phenolic compounds.
Industrial Crops And Products
111
:141-148.
doi: 10.1016/j.indcrop.2017.10.009.
(Impact factor, Quartile: 3.849, Q1).
Hansen solubility parameters (HSP) for prescreening formulation of solid lipid nanoparticles (SLN): in vitro testing of curcumin-loaded SLN in MCF-7 and BT-474 cell lines.
Doktorovova, Slavomira; Souto, Eliana B.; Silva, Amelia M.
(2018)
Hansen solubility parameters (HSP) for prescreening formulation of solid lipid nanoparticles (SLN): in vitro testing of curcumin-loaded SLN in MCF-7 and BT-474 cell lines.
Pharmaceutical Development And Technology
23
(1)
:96-105.
doi: 10.1080/10837450.2017.1384491.
(Impact factor, Quartile: 1.945, Q3).
Linalool Bioactive Properties and Potential Applicability in Drug Delivery Systems.
Pereira, I.; Severino, Patrícia; Santos, Ana C.; Silva, Amélia M.; Souto, Eliana B.
(2018)
Linalool Bioactive Properties and Potential Applicability in Drug Delivery Systems.
Colloids And Surfaces B-Biointerfaces
171
:566-578.
doi: 10.1016/j.colsurfb.2018.08.001.
(Impact factor, Quartile: 3.997, Q1).
Mediterranean essential oils as precious matrix components and active ingredients of lipid nanoparticles.
Carbone, C.; Martins-Gomes, C.; Caddeo, C.; Silva, A. M.; Musumeci, T.; Pignatello, R.; Puglisi, G.; Souto, E. B.
(2018)
Mediterranean essential oils as precious matrix components and active ingredients of lipid nanoparticles.
International Journal Of Pharmaceutics
548
(1)
:217-226.
doi: 10.1016/j.ijpharm.2018.06.064.
(Impact factor, Quartile: 3.862, Q1).
Memantine loaded PLGA PEGylated nanoparticles for Alzheimer's disease: in vitro and in vivo characterization.
Sanchez-Lopez, Elena; Ettcheto, Miren; Antonia Egea, Maria; Espina, Marta; Cano, Amanda; Cristina Calpena, Ana; Camins, Antoni; Carmona, Nuria; Silva, Amelia M.; Souto, Eliana B.; Luisa Garcia, Maria
(2018)
Memantine loaded PLGA PEGylated nanoparticles for Alzheimer's disease: in vitro and in vivo characterization.
Journal Of Nanobiotechnology
16.
doi: 10.1186/s12951-018-0356-z.
(Impact factor, Quartile: 5.294, Q1).
Memantine-Loaded PEGylated Biodegradable Nanoparticles for the Treatment of Glaucoma.
Sanchez-Lopez, Elena; Antonia Egea, Maria; Davis, Benjamin Michael; Guo, Li; Espina, Marta; Silva, Amelia Maria; Cristina Calpena, Ana; Barbosa Souto, Eliana Maria; Ravindran, Nivedita; Ettcheto, Miren; Camins, Antonio; Luisa Garcia, Maria; Cordeiro, Maria Francesca
(2018)
Memantine-Loaded PEGylated Biodegradable Nanoparticles for the Treatment of Glaucoma.
Small
14
(2).
doi: 10.1002/smll.201701808.
(Impact factor, Quartile: 9.598, Q1).
Optimization of Linalool-loaded Solid Lipid Nanoparticles using Experimental Factorial Design and Long-term Stability Studies with a New Centrifugal Sedimentation Method.
Pereira, I.; Alexandra Zielińska; Nuno R. Ferreira; Amélia M. Silva; Eliana B. Souto
(2018)
Optimization of Linalool-loaded Solid Lipid Nanoparticles using Experimental Factorial Design and Long-term Stability Studies with a New Centrifugal Sedimentation Method.
International Journal Of Pharmaceutics
549
(1)
:261-270.
doi: 10.1016/j.ijpharm.2018.07.068.
(Impact factor, Quartile: 3.862, Q1).
Optimization, Biopharmaceutical Profile and Therapeutic Efficacy of Pioglitazone-loaded PLGA-PEG Nanospheres as a Novel Strategy for Ocular Inflammatory Disorders.
Silva-Abreu, Marcelle; Cristina Calpena, Ana; Espina, Marta; Silva, Amelia M.; Gimeno, Alvaro; Antonia Egea, Maria; Luisa Garcia, Maria
(2018)
Optimization, Biopharmaceutical Profile and Therapeutic Efficacy of Pioglitazone-loaded PLGA-PEG Nanospheres as a Novel Strategy for Ocular Inflammatory Disorders.
Pharmaceutical Research
35
(1).
doi: 10.1007/s11095-017-2319-8.
(Impact factor, Quartile: 3.335, Q2).
Repurposing itraconazole to the benefit of skin cancer treatment: A combined azole-DDAB nanoencapsulation strategy.
Carbone, C.; Martins-Gomes, C.; Pepe, V.; Silva, A. M.; Musumeci, T.; Puglisi, G.; Furneri, P. M.; Souto, E. B.
(2018)
Repurposing itraconazole to the benefit of skin cancer treatment: A combined azole-DDAB nanoencapsulation strategy.
Colloids And Surfaces B-Biointerfaces
167
:337-344.
doi: 10.1016/j.colsurfb.2018.04.031.
(Impact factor, Quartile: 3.997, Q1).
Thymus pulegioides L. as a rich source of antioxidant, anti-proliferative and neuroprotective phenolic compounds.
Taghouti, Meriem; Martins-Gomes, Carlos; Schaefer, Judith; Felix, Luis M.; Santos, Joao A.; Bunzel, Mirko; Nunes, Fernando M.; Silva, Amelia M.
(2018)
Thymus pulegioides L. as a rich source of antioxidant, anti-proliferative and neuroprotective phenolic compounds.
Food & Function
9
(7)
:3617-3629.
doi: 10.1039/c8fo00456k.
(Impact factor, Quartile: 3.289, Q1).
Titanium dioxide nanoparticles: Toxicity and genotoxicity in Drosophila melanogaster (SMART eye-spot test and comet assay in neuroblasts).
Sario, Sara; Silva, Amelia M.; Gaivao, Isabel
(2018)
Titanium dioxide nanoparticles: Toxicity and genotoxicity in Drosophila melanogaster (SMART eye-spot test and comet assay in neuroblasts).
Mutation Research-Genetic Toxicology And Environmental Mutagenesis
831
:19-23.
doi: 10.1016/j.mrgentox.2018.05.001.
(Impact factor, Quartile: 1.996, Q3).
Influence of the stabilizers on the toxicity of metallic nanomaterials in aquatic organisms and human cell lines.
Andreani, T, Nogueira, V, Pinto, VV, Ferreira, MJ, Rasteiro, MG, Silva, AM, Pereira, R, Pereira, CM
(2017)
Influence of the stabilizers on the toxicity of metallic nanomaterials in aquatic organisms and human cell lines.
Science Of The Total Environment
607
:1264-1277.
ISSN: 0048-9697.
doi: 10.1016/j.scitotenv.2017.07.098.
(Impact factor, Quartile: 4.9, Q1).