Amélia Maria Lopes Dias da Silva Full Member

BIO

Name: Amélia Maria Lopes Dias da Silva

Aggregation: Full Member

Orcid ID: 0000-0002-7524-9914

Email: amsilva@utad.pt

URL:

Phone:

Publications

Anti-inflammatory and Anti-cancer Activity of Citral: Optimization of Citral-loaded Solid Lipid Nanoparticles (SLN) using Experimental Factorial Design and LUMiSizer.
Zielińska, Alexandra; Martins-Gomes, Carlos; Ferreira, Nuno R. ; Silva, Amélia M.; Nowak, I.; Souto, Eliana B. (2018) Anti-inflammatory and Anti-cancer Activity of Citral: Optimization of Citral-loaded Solid Lipid Nanoparticles (SLN) using Experimental Factorial Design and LUMiSizer. INTERNATIONAL JOURNAL OF PHARMACEUTICS 553 (2-Jan) :428-440. doi: 10.1016/j.ijpharm.2018.10.065. (Impact factor, Quartile: 3.862, Q1).

Chemical characterization and bioactive properties of decoctions and hydroethanolic extracts of Thymus carnosus Boiss.
Martins-Gomes, Carlos; Taghouti, Meriem; Schaefer, Judith; Bunzel, Mirko; Silva, Amelia M.; Nunes, Fernando M. (2018) Chemical characterization and bioactive properties of decoctions and hydroethanolic extracts of Thymus carnosus Boiss. Journal Of Functional Foods 43 :154-164. doi: 10.1016/j.jff.2018.02.012. (Impact factor, Quartile: 3.47, Q1).

Citrus reticulata Blanco peels as a source of antioxidant and anti-proliferative phenolic compounds.
Ferreira, Sandrine S.; Silva, Amelia M.; Nunes, Fernando M. (2018) Citrus reticulata Blanco peels as a source of antioxidant and anti-proliferative phenolic compounds. Industrial Crops And Products 111 :141-148. doi: 10.1016/j.indcrop.2017.10.009. (Impact factor, Quartile: 3.849, Q1).

Hansen solubility parameters (HSP) for prescreening formulation of solid lipid nanoparticles (SLN): in vitro testing of curcumin-loaded SLN in MCF-7 and BT-474 cell lines.
Doktorovova, Slavomira; Souto, Eliana B.; Silva, Amelia M. (2018) Hansen solubility parameters (HSP) for prescreening formulation of solid lipid nanoparticles (SLN): in vitro testing of curcumin-loaded SLN in MCF-7 and BT-474 cell lines. Pharmaceutical Development And Technology 23 (1) :96-105. doi: 10.1080/10837450.2017.1384491. (Impact factor, Quartile: 1.945, Q3).

Linalool Bioactive Properties and Potential Applicability in Drug Delivery Systems.
Pereira, I.; Severino, Patrícia; Santos, Ana C.; Silva, Amélia M.; Souto, Eliana B. (2018) Linalool Bioactive Properties and Potential Applicability in Drug Delivery Systems. Colloids And Surfaces B-Biointerfaces 171 :566-578. doi: 10.1016/j.colsurfb.2018.08.001. (Impact factor, Quartile: 3.997, Q1).

Mediterranean essential oils as precious matrix components and active ingredients of lipid nanoparticles.
Carbone, C.; Martins-Gomes, C.; Caddeo, C.; Silva, A. M.; Musumeci, T.; Pignatello, R.; Puglisi, G.; Souto, E. B. (2018) Mediterranean essential oils as precious matrix components and active ingredients of lipid nanoparticles. International Journal Of Pharmaceutics 548 (1) :217-226. doi: 10.1016/j.ijpharm.2018.06.064. (Impact factor, Quartile: 3.862, Q1).

Memantine loaded PLGA PEGylated nanoparticles for Alzheimer's disease: in vitro and in vivo characterization.
Sanchez-Lopez, Elena; Ettcheto, Miren; Antonia Egea, Maria; Espina, Marta; Cano, Amanda; Cristina Calpena, Ana; Camins, Antoni; Carmona, Nuria; Silva, Amelia M.; Souto, Eliana B.; Luisa Garcia, Maria (2018) Memantine loaded PLGA PEGylated nanoparticles for Alzheimer's disease: in vitro and in vivo characterization. Journal Of Nanobiotechnology 16. doi: 10.1186/s12951-018-0356-z. (Impact factor, Quartile: 5.294, Q1).

Memantine-Loaded PEGylated Biodegradable Nanoparticles for the Treatment of Glaucoma.
Sanchez-Lopez, Elena; Antonia Egea, Maria; Davis, Benjamin Michael; Guo, Li; Espina, Marta; Silva, Amelia Maria; Cristina Calpena, Ana; Barbosa Souto, Eliana Maria; Ravindran, Nivedita; Ettcheto, Miren; Camins, Antonio; Luisa Garcia, Maria; Cordeiro, Maria Francesca (2018) Memantine-Loaded PEGylated Biodegradable Nanoparticles for the Treatment of Glaucoma. Small 14 (2). doi: 10.1002/smll.201701808. (Impact factor, Quartile: 9.598, Q1).

Optimization of Linalool-loaded Solid Lipid Nanoparticles using Experimental Factorial Design and Long-term Stability Studies with a New Centrifugal Sedimentation Method.
Pereira, I.; Alexandra Zielińska; Nuno R. Ferreira; Amélia M. Silva; Eliana B. Souto (2018) Optimization of Linalool-loaded Solid Lipid Nanoparticles using Experimental Factorial Design and Long-term Stability Studies with a New Centrifugal Sedimentation Method. International Journal Of Pharmaceutics 549 (1) :261-270. doi: 10.1016/j.ijpharm.2018.07.068. (Impact factor, Quartile: 3.862, Q1).

Optimization, Biopharmaceutical Profile and Therapeutic Efficacy of Pioglitazone-loaded PLGA-PEG Nanospheres as a Novel Strategy for Ocular Inflammatory Disorders.
Silva-Abreu, Marcelle; Cristina Calpena, Ana; Espina, Marta; Silva, Amelia M.; Gimeno, Alvaro; Antonia Egea, Maria; Luisa Garcia, Maria (2018) Optimization, Biopharmaceutical Profile and Therapeutic Efficacy of Pioglitazone-loaded PLGA-PEG Nanospheres as a Novel Strategy for Ocular Inflammatory Disorders. Pharmaceutical Research 35 (1). doi: 10.1007/s11095-017-2319-8. (Impact factor, Quartile: 3.335, Q2).

Repurposing itraconazole to the benefit of skin cancer treatment: A combined azole-DDAB nanoencapsulation strategy.
Carbone, C.; Martins-Gomes, C.; Pepe, V.; Silva, A. M.; Musumeci, T.; Puglisi, G.; Furneri, P. M.; Souto, E. B. (2018) Repurposing itraconazole to the benefit of skin cancer treatment: A combined azole-DDAB nanoencapsulation strategy. Colloids And Surfaces B-Biointerfaces 167 :337-344. doi: 10.1016/j.colsurfb.2018.04.031. (Impact factor, Quartile: 3.997, Q1).

Thymus pulegioides L. as a rich source of antioxidant, anti-proliferative and neuroprotective phenolic compounds.
Taghouti, Meriem; Martins-Gomes, Carlos; Schaefer, Judith; Felix, Luis M.; Santos, Joao A.; Bunzel, Mirko; Nunes, Fernando M.; Silva, Amelia M. (2018) Thymus pulegioides L. as a rich source of antioxidant, anti-proliferative and neuroprotective phenolic compounds. Food & Function 9 (7) :3617-3629. doi: 10.1039/c8fo00456k. (Impact factor, Quartile: 3.289, Q1).

Titanium dioxide nanoparticles: Toxicity and genotoxicity in Drosophila melanogaster (SMART eye-spot test and comet assay in neuroblasts).
Sario, Sara; Silva, Amelia M.; Gaivao, Isabel (2018) Titanium dioxide nanoparticles: Toxicity and genotoxicity in Drosophila melanogaster (SMART eye-spot test and comet assay in neuroblasts). Mutation Research-Genetic Toxicology And Environmental Mutagenesis 831 :19-23. doi: 10.1016/j.mrgentox.2018.05.001. (Impact factor, Quartile: 1.996, Q3).

Influence of the stabilizers on the toxicity of metallic nanomaterials in aquatic organisms and human cell lines.
Andreani, T, Nogueira, V, Pinto, VV, Ferreira, MJ, Rasteiro, MG, Silva, AM, Pereira, R, Pereira, CM (2017) Influence of the stabilizers on the toxicity of metallic nanomaterials in aquatic organisms and human cell lines. Science Of The Total Environment 607 :1264-1277. ISSN: 0048-9697. doi: 10.1016/j.scitotenv.2017.07.098. (Impact factor, Quartile: 4.9, Q1).

Projects

FungiTech - Technology and innovation in the production chain of shiitake and other mushrooms with nutraceutical value and medicine
Running

Coordinator  /  Guilhermina Marques
Start date  /  2018/07 Funding  /  Norte2020


Safe NPest: Synthesis and Environmental Safety of Nanopesticides
Running

Coordinator  /  Amélia Silva
Start date  /  2018/07 Funding  /  FCT/FEDER


PAIRED - Magnetically and photochemically actuated bioactive nanowires for remotely controlled drug delivery
Running

Coordinator  /  Amélia Silva
Start date  /  2016/10 Funding  /  European Commission - ERA-NETS


INTERACT - Integrative Research in Environment, Agro-Chains and Technology
Running

Coordinator  /  Rui Cortes
Start date  /  2016/05 Funding  /  NORTE2020


IBERPHENOL- Research cooperation network in polyphenols and its industrial applications”
Running

Coordinator  /  Eduardo Rosa
Start date  /  2015/10 Funding  /  INTERREG - POCTEP (Spain - Portugal)


INNOFOOD - INNOVation in the FOOD sector through the valorization of food and agro-food by-products
Concluded

Coordinator  /  Ana Barros
Start date  /  2014/01


MELHORA DAS PROPRIEDADES DE SAUDE DOS ALIMENTOS, COMPARTILHANDO O CONHECIMENTO SOBRE O PROCESSO DIGESTIVO (INFOGEST)
Concluded

Coordinator  /  Raul Perles
Start date  /  2013/05 Funding  /  European Cooperation in Science and Technology (COST)


NanoSKIN: Nanopartículas contendo agentes quimioterapêuticos para terapias inovadoras de doenças severas da pele – Leishmaniase muco/cutânea e carcinoma espinocelular como exemplos.
Concluded

Coordinator  /  Amélia Silva
Start date  /  2011/05


PromoAgro - Promoção da Competitividade Agro-alimentar
Concluded

Coordinator  /  Eduardo Rosa
Start date  /  2010/10 Funding  /  CCDRN - ON.2


NutriDouro: Frutas confitadas e compotas saudáveis, o sabor tradicional
Concluded

Start date  /  2010/06 Funding  /  QREN-Copromoção